Immunogenicity Trial of 3 Influenza Vaccines
Condition: Influenza Vaccination Interventions: Biological: Flublok Quadrivalent vaccine; Biological: Fluarix Quadrivalent vaccine; Biological: Flucelvax Quadrivalent vaccine Sponsors: Tan Tock Seng Hospital; Sanofi; World Health Organization Collaborating Centre for Reference and Research on Influenza (WHOCCRRI); A*Star Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 29, 2022 Category: Research Source Type: clinical trials
Supporting families to achieve a healthy weight development for their child with overweight/obesity using the STARKIDS intervention: study protocol for a cluster-randomized controlled trial
DiscussionThe stepwise, e-health-supported STARKIDS program is a low-threshold intervention program for families with children/adolescents with overweight/obesity. With the proof of concept, STARKIDS provides the potential to be implemented as a standard care tool for the prevention and intervention of childhood/adolescence obesity in the German health system.Trial registrationGerman Clinical Trials Register (DRKS)DRKS00022813 (acknowledged primary register of the World Health Organization). Registered on 27 November 2020 (Universal Trial Number U1111-1254-9536). (Source: Trials)
Source: Trials - July 23, 2022 Category: Research Source Type: clinical trials
Comparison of 8 weeks standard treatment (rifampicin plus clarithromycin) vs. 4 weeks standard plus amoxicillin/clavulanate treatment [RC8 vs. RCA4] to shorten Buruli ulcer disease therapy (the BLMs4BU trial): study protocol for a randomized controlled multi-centre trial in Benin
DiscussionIf successful, this study will create a new paradigm for BU treatment, which could inform World Health Organization policy and practice. A shortened, highly effective, all-oral regimen will improve care of BU patients and will lead to a decrease in hospitalization-related expenses and indirect and social costs and improve treatment adherence. This trial may also provide information on treatment shortening strategies for other mycobacterial infections (tuberculosis, leprosy, or non-tuberculous mycobacteria infections).Trial registrationClinicalTrials.govNCT05169554. Registered on 27 December 2021. (Source: Trials)
Source: Trials - July 8, 2022 Category: Research Source Type: clinical trials
The clinical effectiveness and cost-effectiveness of a ‘stepping into day treatment’ approach versus inpatient treatment as usual for anorexia nervosa in adult specialist eating disorder services (DAISIES trial): a study protocol of a randomised controlled multi-centre open-label parallel group non-inferiority trial
DiscussionThe results of this study will provide a rigorous evaluation of two intensive treatment approaches which will inform future national and international treatment guidelines and service provision.Trial registrationISRCTNISRCTN10166784. Registered 28 February 2020. ISRCTN is a primary registry of the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) network and includes all items from the WHO Trial Registration Data Set. (Source: Trials)
Source: Trials - June 16, 2022 Category: Research Source Type: clinical trials
ALIMUS —We are feeding! Study protocol of a multi-center, cluster-randomized controlled trial on the effects of a home garden and nutrition counseling intervention to reduce child undernutrition in rural Burkina Faso and Kenya
DiscussionThis project will establish the potential of a home gardening and nutrition counseling program to counteract climate change-related quantitative and qualitative agricultural losses, thereby improving the nutritional status among young children in rural sub-Saharan Africa.Trial registrationGerman Clinical Trials Register (DRKS)DRKS00019076. Registered on 27 July 2021. (Source: Trials)
Source: Trials - June 1, 2022 Category: Research Source Type: clinical trials
