Emergent microenvironments of nucleoli
Volume 15, Issue 1, December 2024 . (Source: Nucleus)
Source: Nucleus - March 6, 2024 Category: Molecular Biology Authors: Matthew R. KingKiersten M. RuffRohit V. PappuDepartment of Biomedical Engineering and Center for Biomolecular Condensates, Washington University in St. Louis, Campus, MO, USA Source Type: research
Surprise RNAs solve mystery of how butterfly wings get their colorful patterns
A mutant butterfly for sale on eBay has helped upend naturalists’ picture of how butterfly wings acquire their intricate variety of red, yellow, white, and black stripes. It and recent research into other butterflies shows how visible traits in many animals may be controlled by the same underexplored genetic regulatory mechanism, based not on proteins, but on RNA.
In 2016, geneticists thought they had pinned much of the wing-pattern variation
on a protein-encoding gene called
cortex
. But three teams have now proved that a different gene, previously missed because it overlaps with
cortex
...
Source: Science of Aging Knowledge Environment - February 29, 2024 Category: Geriatrics Source Type: research
Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements
The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9–11, 2023 in Gainesville, Florida with the theme of “Pushing the Forefront of Neuromodulation”. The keynote speaker was Dr. Nico Dosenbach from Washington University in St. Louis, Missouri. He presented his research recently published in Nature inn a collaboration with Dr. Evan Gordon to identify and characterize the somato-cognitive action network (SCAN), which has redefined the motor homunculus and has led to new hypotheses about the integrative networks underpinning therapeutic DBS. The DBS Think Tank was founded in 2012 and provides an open platfo...
Source: Frontiers in Human Neuroscience - February 21, 2024 Category: Neuroscience Source Type: research
Does fluoride in drinking water lower IQ? Question looms large in court battle
A long-simmering scientific battle took on new life this week, as experts clashed in a San Francisco courtroom over whether the U.S. Environmental Protection Agency (EPA) should ban fluoridation of drinking water to protect fetuses and children from the risk of neurodevelopmental problems.
The
case
, being heard in a federal district court, “is precedent setting,” says Lynn Bergeson, a managing partner of Bergeson & Campbell who focuses on chemical toxicity. Rarely have judges had to “manage the enormity of this record of scientific evidence. … That’s why there’s a lot of attention focused o...
Source: Science of Aging Knowledge Environment - February 2, 2024 Category: Geriatrics Source Type: research
Peripheral Retinal Haemorrhages in a Patient with MOG-Associated Optic Neuritis
. (Source: Neuro-Ophthalmology)
Source: Neuro-Ophthalmology - January 26, 2024 Category: Opthalmology Authors: Georgia A. WilkeMadeline SpencerCarley A. GilmanRejean GuerrieroParker BohmGregory P. Van StavernAndrew R. Leea Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, Missouri, USAb Department of Paediatrics, Washi Source Type: research
Why does COVID-19 make you sneeze?
SARS-CoV-2 has many ways of making people miserable, including by causing them to sneeze. Now, researchers have discovered the basis for this nose-tickling effect. One of the virus’ proteins stimulates neurons in respiratory passages, triggering the sneeze reflex. The results could spawn novel treatments to ease COVID-19 symptoms and to reduce transmission of SARS-CoV-2.
They might also apply to other sneeze-inciting viruses. “Prior to this study, nothing was known about how viruses cause sneezing,” says neuroimmunologist Isaac Chiu of Harvard Medical School, who wasn’t connected to the research. The study is...
Source: Science of Aging Knowledge Environment - January 23, 2024 Category: Geriatrics Source Type: research
AASM Scoring Manual 3: a step forward for advancing sleep care for patients with obstructive sleep apnea
Journal of Clinical Sleep Medicine, Ahead of Print. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - January 22, 2024 Category: Sleep Medicine Authors: Raman K. Malhotra
Sleep Medicine Center, Washington University School of Medicine, St. Louis, Missouri Source Type: research
Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation
Researchers say the genetically engineered stem cells also could pave the way for new regenerative medicine treatments for diseases such as Type 1 diabetes.
Tuesday
University of Arizona Health SciencesDeepta Bhattacharya
Deepta Bhattacharya, who is on the University of Arizona Health Sciences Center for Advanced Molecular and Immunological Therapies advisory council, is a professor of immunobiology in the UArizona College of Medicine – Tucson.
UArizona Health SciencesHealthScience and TechnologyBIO5Cancer CenterCollege of Medicine - TucsonMedicineScienceTech Launch Arizona
Media contact(s)Phil Villarreal
Univers...
Source: The University of Arizona: Health - January 11, 2024 Category: Universities & Medical Training Authors: lburtchbuus Source Type: research
Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation
lburtchbuusThu, 01/11/2024 - 11:41Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantationImageDeepta Bhattacharya, who is on the University of Arizona Health Sciences Center for Advanced Molecular and Immunological Therapies advisory council, is a professor of immunobiology in the UArizona College of Medicine – Tucson.UArizona Health SciencesJan. 16, 2024Byline AffiliationUniversity of Arizona Health SciencesOne of the biggest barriers to regenerative medicine is immunological rejection by the recipient, a problem researchers at theUniversity of Arizona Health Scien...
Source: The University of Arizona: Health - January 11, 2024 Category: Universities & Medical Training Authors: lburtchbuus Source Type: research
Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - January 8, 2024 Category: Microbiology Authors: Valentin GreigertIti SaraavJuhee SonYinxing ZhuDenise DayaoAvan AntiaSaul TziporiWilliam H. WitolaThaddeus S. StappenbeckSiyuan DingL. David Sibleya Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USAb Depart Source Type: research
Saponin TQL1055 adjuvant-containing vaccine confers protection upon Mycobacterium tuberculosis challenge in mice
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - January 8, 2024 Category: Allergy & Immunology Authors: Mushtaq AhmedEric FarrisRosemary V. SwansonShibali DasYan YangTyler MartinShabaana A. Khadera Department of Microbiology, University of Chicago, Chicago, IL, USAb Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO, USA Source Type: research
Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - January 8, 2024 Category: Microbiology Authors: Valentin GreigertIti SaraavJuhee SonYinxing ZhuDenise DayaoAvan AntiaSaul TziporiWilliam H. WitolaThaddeus S. StappenbeckSiyuan DingL. David Sibleya Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USAb Depart Source Type: research
