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Risk of pre-term birth as a function of sleep quality and obesity: prospective analysis in a large Prematurity Research Cohort
CONCLUSION: Our findings suggest that improving sleep quality early in pregnancy may be important for PTB prevention, particularly among individuals with obesity.PMID:37965625 | PMC:PMC10642756 | DOI:10.1093/sleepadvances/zpad043 (Source: Adv Data)
Source: Adv Data - November 15, 2023 Category: Epidemiology Authors: Siobhan Sutcliffe Peinan Zhao Luisa Klaus Pilz Megan Oakes Antonina I Frolova Erik D Herzog Sarah K England Source Type: research

Base editing, a new form of gene therapy, sharply lowers bad cholesterol in clinical trial
A technique for precisely rewriting the genetic code directly in the body has slashed “bad” cholesterol levels—possibly for life—in three people prone to dangerously high levels of the artery-clogging fat. The feat relied on a blood infusion of a so-called base editor, designed to disable a liver protein, PCSK9, that regulates cholesterol. “It is a breakthrough to have shown in humans that in vivo base editing works efficiently in the liver,” says Gerald Schwenk, a gene editing researcher at the University of Zurich who wasn’t involved in the clinical trial, sponsored by the biotech Verve Therapeutics. ...
Source: Science of Aging Knowledge Environment - November 12, 2023 Category: Geriatrics Source Type: research

Impending sale of scientifically critical helium sparks worries
After serving as the world’s largest provider of helium for nearly a century, the U.S. government is close to bowing out of the market. Aiming to recoup costs, it began emptying its vast underground reservoir of the gas in the 1990s and has now put the whole federal helium system up for sale. Early next year, the government plans to unveil bids from potential buyers of the Amarillo, Texas, facility, which includes a distribution pipeline and the porous rock formation containing the remaining stores of helium—a substance used in everything from MRI machines to quantum computers to party balloons. But few are celeb...
Source: Science of Aging Knowledge Environment - November 6, 2023 Category: Geriatrics Source Type: research

From Digital Commons to Alma/Primo: enhancing the dissemination of Doctor of Nursing Practice (DNP) projects
J Med Libr Assoc. 2023 Oct 2;111(4):835-836. doi: 10.5195/jmla.2023.1624.ABSTRACTThe Doctor of Nursing Practice (DNP) project collection is a group of approximately 120 DNP projects archived between 2017 and 2022 in Health Sciences Research Commons (HSRC), the health sciences institutional repository (IR) for the George Washington University. Our project focused on expanding avenues for the dissemination of DNP projects beyond our Digital Commons IR by integrating this content into the library's instances of Ex Libris Alma and Primo VE. By utilizing the Ex Libris Repository type import profile rather than the OAI-PMH feed,...
Source: J Med Libr Assoc AND... - November 6, 2023 Category: Databases & Libraries Authors: Sara Hoover Source Type: research

From Digital Commons to Alma/Primo: enhancing the dissemination of Doctor of Nursing Practice (DNP) projects
J Med Libr Assoc. 2023 Oct 2;111(4):835-836. doi: 10.5195/jmla.2023.1624.ABSTRACTThe Doctor of Nursing Practice (DNP) project collection is a group of approximately 120 DNP projects archived between 2017 and 2022 in Health Sciences Research Commons (HSRC), the health sciences institutional repository (IR) for the George Washington University. Our project focused on expanding avenues for the dissemination of DNP projects beyond our Digital Commons IR by integrating this content into the library's instances of Ex Libris Alma and Primo VE. By utilizing the Ex Libris Repository type import profile rather than the OAI-PMH feed,...
Source: Journal of the Medical Library Association : JMLA - November 6, 2023 Category: Databases & Libraries Authors: Sara Hoover Source Type: research