Role of kinin receptors in skin pigmentation
Eur J Pharmacol. 2024 Apr 9:176537. doi: 10.1016/j.ejphar.2024.176537. Online ahead of print.ABSTRACTPrevious studies have shown that all kinin system is constitutively expressed in the normal and inflamed skin, with a potential role in both physiological and pathological processes. However, the understanding regarding the involvement of the kinin system in skin pigmentation and pigmentation disorders remains incomplete. In this context, the present study was designed to determine the role of kinins in the Monobenzone (MBZ)-induced vitiligo-like model. Our findings showed that MBZ induces higher local skin depigmentation i...
Source: European Journal of Pharmacology - April 11, 2024 Category: Drugs & Pharmacology Authors: Juliana de Cassia Pinto Ferreira Bruna Silva Soley Priscila Lucia Pawloski Camila Guimar ães Moreira Jo ão Bosco Pesquero Michael Bader Jo ão Batista Calixto Daniela Almeida Cabrini Michel Fleith Otuki Source Type: research
Role of kinin receptors in skin pigmentation
Eur J Pharmacol. 2024 Apr 9:176537. doi: 10.1016/j.ejphar.2024.176537. Online ahead of print.ABSTRACTPrevious studies have shown that all kinin system is constitutively expressed in the normal and inflamed skin, with a potential role in both physiological and pathological processes. However, the understanding regarding the involvement of the kinin system in skin pigmentation and pigmentation disorders remains incomplete. In this context, the present study was designed to determine the role of kinins in the Monobenzone (MBZ)-induced vitiligo-like model. Our findings showed that MBZ induces higher local skin depigmentation i...
Source: European Journal of Pharmacology - April 11, 2024 Category: Drugs & Pharmacology Authors: Juliana de Cassia Pinto Ferreira Bruna Silva Soley Priscila Lucia Pawloski Camila Guimar ães Moreira Jo ão Bosco Pesquero Michael Bader Jo ão Batista Calixto Daniela Almeida Cabrini Michel Fleith Otuki Source Type: research
Association between miR-202, miR-211, and miR-1238 gene polymorphisms and risk of vitiligo
AbstractVitiligo, as a common pigment defect in the skin, hair, and mucous membranes, results from the destruction of melanocytes. Recent investigations have shown that miRNA dysregulation contributes in the pathogenesis of vitiligo. Therefore, in this research, our aim is to explore the relationship between miR-202 rs12355840, miR-211 rs8039189, and miR-1238 rs12973308 polymorphisms and susceptibility to vitiligo. A total number of 136 vitiligo patients and 129 healthy individuals as a control group were included in this research. The salting out approach was implemented to extraction genomic DNA. The genetic polymorphism...
Source: Archives of Dermatological Research - April 10, 2024 Category: Dermatology Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
Pediatric Dermatology for People of Color
Pediatr Ann. 2024 Apr;53(4):e146-e151. doi: 10.3928/19382359-20240205-07. Epub 2024 Apr 1.ABSTRACTWhen evaluating pediatric patients of color, it is essential to consider the unique diagnostic and treatment factors that apply to this population. Certain dermatologic conditions are more common in these patients, including postinflammatory hyperpigmentation, pityriasis alba, progressive macular hypomelanosis, tinea capitis, traction alopecia, keloids, hypertrophic scars, pseudofolliculitis barbae, acne keloidalis nuchae, and hidradenitis suppurativa. Furthermore, conditions such as vitiligo are more noticeable in people of c...
Source: Pediatric Annals - April 4, 2024 Category: Pediatrics Authors: Muayad M Shahin Henry T Quach Kalyani S Marathe Source Type: research
