Trial By Error: Can Functional Neurological Disorder Be an Indication of Prion Disease?
By David Tuller, DrPH A recent article in the Journal of Neurology presents a twist on the issue of functional neurological disorder (FND). The article, which was published in September, is called “Functional neurological symptoms as initial presentation of Creutzfeldt‐Jakob disease: case series.” Creutzfeldt-Jakob disease is a prion disorder that leads to dementia and death, … Trial By Error: Can Functional Neurological Disorder Be an Indication of Prion Disease? Read More » (Source: virology blog)
Source: virology blog - December 22, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS FND functional neurological disorder prions Source Type: blogs
Trial By Error: A Stupid Study of Exercise for Long Covid Patients With Post-Exertional Symptom Exacerbation
By David Tuller, DrPH The Journal of Medical Virology has just published a study called “Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome.” The investigators are from the University of Leeds and the Leeds Community Healthcare NHS Trust. Post-COVID-19 syndrome (PCS) […] (Source: virology blog)
Source: virology blog - December 20, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Leeds Long Covid PESE Source Type: blogs
Trial By Error: A Stupid Study of Exercise for Long Covid Patients With Post-Exertional Symptom Exacerbation
By David Tuller, DrPH The Journal of Medical Virology has just published a study called “Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome.” The investigators are from the University of Leeds and the Leeds Community Healthcare NHS Trust. Post-COVID-19 syndrome (PCS) … Trial By Error: A Stupid Study of Exercise for Long Covid Patients With Post-Exertional Symptom Exacerbation Read More » (Source: virology blog)
Source: virology blog - December 20, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS Leeds Long Covid PESE Source Type: blogs
Trial By Error: Is the Long Covid Phenomenon an Expression of “ Psychosocial Distress ” ?
By David Tuller, DrPH For the second time in a few weeks, a major US news organization has provided Professor Michael Sharpe, lead PACE investigator and one-time Virology Blog commenter, with a high-profile platform to disseminate his typical blather and nonsense. Both articles—the first in New York Magazine, the second in The New Republic–-have presented […] (Source: virology blog)
Source: virology blog - December 14, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Long Covid natalie shure new republic new york magazine Source Type: blogs
Trial By Error: Is the Long Covid Phenomenon an Expression of “ Psychosocial Distress ” ?
By David Tuller, DrPH For the second time in a few weeks, a major US news organization has provided Professor Michael Sharpe, lead PACE investigator and one-time Virology Blog commenter, with a high-profile platform to disseminate his typical blather and nonsense. Both articles—the first in New York Magazine, the second in The New Republic–-have presented … Trial By Error: Is the Long Covid Phenomenon an Expression of “Psychosocial Distress”? Read More » (Source: virology blog)
Source: virology blog - December 14, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS Long Covid natalie shure new republic new york magazine Source Type: blogs
Trial By Error: Top Lightning Process Proponent Privately Lobbied for Approval of Norway ’ s LP Study
By David Tuller, DrPH Dr Signe Flottorp is a promoter of the Lightning Process for ME/CFS as well as the research director at the Norwegian Institute of Public Health. That’s a scary combination! Dr Flottorp, a general practitioner, is also a fervent member of the Scandinavian arm of the CBT/GET ideological brigades. She and two […] (Source: virology blog)
Source: virology blog - December 8, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized flottorp Lightning Process norway Steinkopf Source Type: blogs
Trial By Error: Top Lightning Process Proponent Privately Lobbied for Approval of Norway ’ s LP Study
By David Tuller, DrPH *Two corrections had been made in the text below. The NEM committee has 12 members, not nine, as I originally wrote. And when Dr Flottorp wrote her letter, it was not while the NEM committee was considering the proposed Lightning Process trial, as I originally wrote, but before it had progressed … Trial By Error: Top Lightning Process Proponent Privately Lobbied for Approval of Norway’s LP Study Read More » (Source: virology blog)
Source: virology blog - December 8, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS flottorp Lightning Process norway Steinkopf Source Type: blogs
Trial By Error: Recent Articles in The Guardian, CNBC and Popular Science
By David Tuller, DrPH As part of an ongoing project on long Covid, The Guardian recently published a powerful excerpt from a book called “What Doesn’t Kill Us Makes Us: Who We Become After Tragedy and Trauma.” The author, Mike Mariani, is an American journalist who a decade ago found himself smacked with a debilitating […] (Source: virology blog)
Source: virology blog - December 6, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized CNBC Guardian Popular Science press Source Type: blogs
Trial By Error: Recent Articles in The Guardian, CNBC and Popular Science
By David Tuller, DrPH As part of an ongoing project on long Covid, The Guardian recently published a powerful excerpt from a book called “What Doesn’t Kill Us Makes Us: Who We Become After Tragedy and Trauma.” The author, Mike Mariani, is an American journalist who a decade ago found himself smacked with a debilitating … Trial By Error: Recent Articles in The Guardian, CNBC and Popular Science Read More » (Source: virology blog)
Source: virology blog - December 6, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS CNBC Guardian Popular Science press Source Type: blogs
“Paxlovid Rebound” Is Just COVID Rebound
by Gertrud U. Rey The antiviral drug Paxlovid is highly effective at inhibiting SARS-CoV-2 replication and reducing symptoms associated with COVID-19. Nevertheless, there have recently been numerous reports of recurrence of positive tests and symptoms after completing treatment with Paxlovid, leading some to infer that the drug triggers the recurrence. Is this inference actually correct, […] (Source: virology blog)
Source: virology blog - December 1, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey antiviral antiviral drug COVID rebound COVID-19 Michael Mina Paxlovid Paxlovid rebound prospective study rapid antigen test retrospective study SARS-CoV-2 symptom rebound viral rebound Source Type: blogs
“Paxlovid Rebound” Is Just COVID Rebound
by Gertrud U. Rey The antiviral drug Paxlovid is highly effective at inhibiting SARS-CoV-2 replication and reducing symptoms associated with COVID-19. Nevertheless, there have recently been numerous reports of recurrence of positive tests and symptoms after completing treatment with Paxlovid, leading some to infer that the drug triggers the recurrence. Is this inference actually correct, … “Paxlovid Rebound” Is Just COVID Rebound Read More » (Source: virology blog)
Source: virology blog - December 1, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey antiviral antiviral drug COVID rebound COVID-19 Michael Mina Paxlovid Paxlovid rebound prospective study rapid antigen test retrospective study SARS-CoV-2 symptom rebound viral rebound Source Type: blogs
Toolbox to Study Ligand Binding for Enhanced Treatments
Researchers at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have developed a DNA toolbox that allows researchers to explore binding interactions between ligands and their respective receptors based on receptor density and arrangement. The basis for many pharmacological interactions between drugs and cells, and indeed many physiological or pathological interactions involving biological signaling molecules, involves a molecule, termed a ligand, binding to a receptor that is typically present on the cell membrane. This binding is highly specific, but it can be influenced by the density of ligands present. ...
Source: Medgadget - November 24, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Public Health EPFL ligand binding Source Type: blogs
Trial By Error: The Long COVID Survival Guide and the Role of Patients in Research
By David Tuller, DrPH “The Long COVID Survival Guide: How to Take Care of Yourself and What Comes Next—Stories and Advice from Twenty Long-Haulers and Experts” is pretty much what it sounds like. The anthology was published earlier this month, and each chapter is written by one or more contributors. The topics covered address long […] (Source: virology blog)
Source: virology blog - November 22, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized fiona lowenstein Long Covid Source Type: blogs
Trial By Error: The Long COVID Survival Guide and the Role of Patients in Research
By David Tuller, DrPH “The Long COVID Survival Guide: How to Take Care of Yourself and What Comes Next—Stories and Advice from Twenty Long-Haulers and Experts” is pretty much what it sounds like. The anthology was published earlier this month, and each chapter is written by one or more contributors. The topics covered address long … Trial By Error: The Long COVID Survival Guide and the Role of Patients in Research Read More » (Source: virology blog)
Source: virology blog - November 22, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS fiona lowenstein Long Covid Source Type: blogs
TWiV 954: Speculating sarbecovirus spillovers with Michael Letko
Michael Letko joins TWiV to discuss his research on understanding cell receptors required for sarbecovirus entry, including an ACE2-dependent isolate from Russian bats that is resistant to vaccine-induced antibodies. (Source: virology blog)
Source: virology blog - November 13, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology ACE2 cell entry coronavirus COVID-19 Khosta virus pandemic RBD sarbecovirus SARS-CoV-2 Tmprss2 trypsin viral viruses Source Type: blogs
