Transmission of Enteric Viruses through Saliva
by Gertrud U. Rey Norovirus and rotavirus are considered to be enteric pathogens because they are traditionally thought to be transmitted by the fecal-oral route; i.e., when consuming food prepared by someone who did not wash their hands properly after using the bathroom. Unlike rabies virus, which replicates in the salivary glands and transmits through […] (Source: virology blog)
Source: virology blog - August 4, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey enteric virus fecal-oral route IgA mammary glands norovirus rotavirus saliva salivary glands SIGA transmission Source Type: blogs

Trial By Error: Is POTS a “ Functional Psychogenic Disorder ” ? Yes, According to NYU Research Team
By David Tuller, DrPH Research into conditions categorized as “medically unexplained symptoms” (MUS) or “functional” disorders seems rife with studies that eagerly interpret associations and correlations as causal relationships. Not surprisingly, these proposed causal relationships tend to flow in the direction required by the investigators’ hypotheses, not in the direction that would undermine their arguments. […] (Source: virology blog)
Source: virology blog - August 3, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized causal New York University POTS Putrino Source Type: blogs

Trial By Error: A Few Things I ’ ve Read (or Heard) Lately About ME/CFS and Long Covid
By David Tuller, DrPH Here are a few things I’ve recently read (or listened to). FreakonomicsMD podcast The Freakonomics brand is well-known in the US. I didn’t realize there was a Freakonomics, M.D. podcast until I listened to this recent half-hour episode. The podcast is hosted by Dr Bapu Jena, a physician and economist at […] (Source: virology blog)
Source: virology blog - August 2, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Freakonomics Jeremy Devine Kahn-Harris Yochai Re'em Source Type: blogs

Trial By Error: Professor Chalder Reports CBT Does Not Work for Post-Stroke Fatigue, Calls for More Research
By David Tuller, DrPH Calling out a Trudie Chalder paper is way too easy. It’s also old hat for Virology Blog—going back to 2015 and my initial investigation into the now-discredited PACE trial, of which she was one of three lead investigators. She is a professor of “cognitive behavioural psychotherapy” at King’s College London, so […] (Source: virology blog)
Source: virology blog - July 26, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized chalder fatigue stroke Source Type: blogs

Trial By Error: A Conversation with Patient Advocate Adam “ Beyonce Holes ” Lowe
By David Tuller, DrPH Adam Lowe, known in some incarnations as Beyonce Holes, is a longtime ME/CFS patient and advocate in Manchester, England, served as a lay member of the committee that produced the new clinical guidance published last October by the UK’s National Institute for Health and Care Excellence. (This conversation was a follow-up […] (Source: virology blog)
Source: virology blog - July 26, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Polio in New York
Virologist Vincent Racaniello breaks down the first case of polio in the US in nearly a decade. (Source: virology blog)
Source: virology blog - July 22, 2022 Category: Virology Authors: Vincent Racaniello Tags: Basic virology IPV OPV polio polio vaccine polio vaccine derived virus poliomyelitis viral viruses Source Type: blogs

Trial By Error: Mom Speaks Out About NHS “ Abuse ” of Daughter; Norway Approves Lightning Process Study
By David Tuller, DrPH On Monday, The Times (UK) published a story about a 17-year-old girl with ME who has experienced hospital treatment that her family has referred to as “neglect and abuse.”  The details are harrowing—but should not be unfamiliar to people aware of similar experiences reported by other teenagers with severe ME. Parents […] (Source: virology blog)
Source: virology blog - July 21, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

TWiV 919: Motivated by volatiles
TWiV reviews the FDA decision to update COVID-19 vaccine boosters in the fall, the meaning of fatigue with respect to long COVID, and a skin volatile induced by flavivirus reproduction that attracts mosquitoes to the infected host. (Source: virology blog)
Source: virology blog - July 18, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology acetophenone antimicrobial peptide coronavirus COVID-19 FDA flavivirus Long Covid mosquito mosquito attractant Omicron booster pandemic SARS-CoV-2 skin microbiome vaccine viral viruses Source Type: blogs

TWiV 918: COVID-19 clinical update #123 with Dr. Daniel Griffin
In COVID-19 clinical update #123, Dr. Griffin discusses rapid diagnostic testing in response to the monkeypox outbreak, leading causes of death in the US during the COVID-19 pandemic, antibody evasion by subvariants, broadly-neutralizing antibodies against emerging variants, factors associated with severe outcomes among hospitalized immunocompromised adults, measurement of the burden of hospitalizations during the pandemic, parental vaccine hesitancy in diverse communities, evaluating saliva sampling to improve access to diagnosis in low-resource settings, oral sabizabulin for high-risk hospitalized adults, lower-risk of m...
Source: virology blog - July 16, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody Omicron pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 14, 2022 Edition-----The biggest news this week was the assassination of the ex-PM of Japan – Shinzo Abe – who was a good friend to OZ incidentally.In the US we have had a wind-up to a busy summit season – NATO etc – and the ongoing war in Ukraine which is becoming a deepening, protracted and horrible situation which it seems hard to resolve sadly.In the UK Boris is out but not gone and the battle for the succession is off and rolling.In OZ we have Albo back and we need to work out what to mitigate these various natural disasters and actually get on with it!!!! The response has been pathetic so far I reckon!--...
Source: Australian Health Information Technology - July 14, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Trial By Error: My Letter to BMJ Paediatrics Open About Missing Peer Reviews for Crawley Paper
By David Tuller, DrPH I recently noted that BMJ Paediatrics Open did not publish the peer review history of a 2021 study from a team led by Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and grant magnet. The study (Clery et al) was titled “Qualitative study of the acceptability and feasibility of […] (Source: virology blog)
Source: virology blog - July 13, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ Paediatrics Open Crawley Source Type: blogs

Trial By Error: If Professor Crawley ’ s ACT Study Was Peer Reviewed, Where Are the Peer Reviews?
By David Tuller, DrPH Yesterday, I wrote a blog about a just-published but already out-dated conference abstract from a team led by Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and grant magnet. After I tweeted about it, I heard from Naomi Harvey, a zoologist, who said she’d written to BJPsychOpen about the […] (Source: virology blog)
Source: virology blog - July 12, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized acceptance and commitment therapy BMJ Crawley Source Type: blogs

Trial By Error: Professor Crawley Promotes Acceptance and Commitment Therapy for CBT Failures
By David Tuller, DrPH What is going on with Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and grant magnet? And why is she still disseminating misguided views about treatments for vulnerable children? Haven’t kids suffered enough from the discredited claims of the GET/CBT ideological brigades? Just last week, the East Kent Hospitals […] (Source: virology blog)
Source: virology blog - July 11, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized acceptance and commitment therapy Crawley Source Type: blogs

Trial By Error: A Letter About the Inflated Prevalence Rate of Functional Neurological Disorder
By David Tuller, DrPH I have recently written two posts (here and here) about how experts in functional neurological disorder (FND) have a tendency to assert prevalence rates that ignore their own diagnostic criteria. Today I sent a letter to the corresponding author of yet another paper that has similarly engaged in this problematic strategy. […] (Source: virology blog)
Source: virology blog - July 7, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS FND functional neurological disorder Source Type: blogs

Should we be worried about monkeypox?
Although monkeypox cases continue to increase around the world, the average person is at low risk of becoming infected. (Source: virology blog)
Source: virology blog - July 7, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey Information acam2000 antiviral drug bifurcated needle bodily fluids brincidofovir fluid-filled vesicles Jynneos lesion men who have sex with men monkeypox MVA-BN Poxviridae ring vaccination sexual Source Type: blogs