Striking increases in postmortem compared to antemortem drug concentrations in a suicidal overdose: a case report - McIntyre IM, Mallett P, Stolberg S, Haas EA, Mena O.
Toxicology testing revealed dramatic increases in whole-blood concentrations of verapamil and diphenhydramine in the short time between hospital admission and death (53 min) in a subject (with a history of overdosing) found unresponsive. While some degree ... (Source: SafetyLit)
Source: SafetyLit - August 12, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Tarka (Trandolapril and Verapamil ER) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 25, 2016 Category: Drugs & Pharmacology Source Type: news
Do you know the answer to this tough USMLE Step 2 question?
If you’re gearing up to take the United States Medical Licensing Examination® (USMLE®) Step 2, get this month’s exclusive scoop on the most missed USMLE Step 2 test prep question and expert strategies to help you master it. Think you have what it takes to rise above your peers? Test your USMLE knowledge, and view an expert video explanation of the answer from Kaplan Medical.
Once you’ve got this question under your belt, be sure to test your knowledge with other posts in this series.
Ready. Set. Go.
This month’s question that stumped most students:
A 57-year-old female with a history of hypertension comes...
Source: AMA Wire - April 28, 2016 Category: Journals (General) Authors: Troy Parks Source Type: news
Type 1 Diabetes Cure?
BIRMINGHAM, Ala. (Ivanhoe Newswire) -- A medication called Verapamil is a common treatment for controlling blood pressure, but researchers have stumbled onto another possible use for it: curing type-one diabetes. A first-of-its-kind trial is now underway, and it could be the cure for what is currently the seventh leading cause of death in the U.S. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - March 15, 2016 Category: Consumer Health News Source Type: news
First Human Data Show Verapamil Lowers Glucose in DiabetesFirst Human Data Show Verapamil Lowers Glucose in Diabetes
Early research hints that this old antihypertensive drug may also lower serum glucose, especially in patients with type 1 or late-stage type 2 diabetes who are on insulin. Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - February 29, 2016 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
Diabetics who use verapamil have lower glucose levels, data show
While causal relationship cannot be inferred, findings of a new study are “absolutely encouraging," says the lead author of a new report. The study shows for the first time that there is an association of verapamil use and lower fasting glucose levels in humans with diabetes (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 12, 2016 Category: Science Source Type: news
Verapamil Hydrochloride (Verapamil Hydrochloride Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 22, 2016 Category: Drugs & Pharmacology Source Type: news
verapamil (Calan, Verelan, Verelan PM [Discontinued: Isoptin, Isoptin SR, Covera-HS])
Title: verapamil (Calan, Verelan, Verelan PM [Discontinued: Isoptin, Isoptin SR, Covera-HS])Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 10/13/2015 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - October 13, 2015 Category: Cardiology Source Type: news
TPR Podcast Episode #8: Pearls from NACCT
Discussion of Dr. Millard Bass’ JAMA article “Sudden Sniffing Death” (SSD)
SSD occurs after sniffing, bagging, or huffing a volatile hydrocarbon inhalant
Hypothesis: death results from sensitization of the myocardium to catecholamines, resulting in cardiac arrhythmias
Capsaicin for Cannabinoid Hyperemesis Syndrome
Initial idea to use capsaicin in the treatment of cannabinoidhyperemesis syndrome (CHS) stemmed from:
Symptomatic relief from hot showers or baths often reported by patients
Realization that TRPV1 receptor is activated by both hot temperatures and capsaicin
Case reports from California and Ne...
Source: The Poison Review - March 1, 2015 Category: Toxicology Authors: LeonThe Poison Review Tags: Podcast cannabinoid hyperemesis syndrome capsaicin cream clenbuterol NACCT phenibut sudden sniffing death syndrome tpr podcast Source Type: news
Glenmark gets USFDA nod to sell generic blood pressure drug Tarka
The approval for trandolapril and verapamil hydrochloride extended release tablets has been granted to Glenmark Generics Inc. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - February 26, 2015 Category: Pharmaceuticals Source Type: news
Diabetes Discovery: Heart Drug Spares Beta Cells In Lab
(MedPage Today) -- Can verapamil preserve beta cell function in type 1 diabetes? (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - January 20, 2015 Category: Cardiology Source Type: news
Whole bowel irrigation? Don’t just do something, stand there!
3.5 out of 5 stars
Position paper update: Whole bowel irrigation for gastrointestinal decontamination of overdose patients. Thanacoody R et al. Clin Toxicol 2015 Jan;53:5-12.
Abstract
In 1997 the American Academy of Clinical Toxicology (AACT) and the Euroopean Association of Poisons Centre and Clinical Toxicologists (EAPCCT) published a position paper regarding the use of whole bowel irrigation (WBI) for gastrointestinal decontamination in the poisoned patient. The key conclusions were that no evidence existed showing that WBI improved clinical outcome, and that it should not be used routinely but “may be considered...
Source: The Poison Review - January 13, 2015 Category: Toxicology Authors: Leon Tags: Medical gastrointestinal decontamination overdose poisoning polyethylene glycol position paper whole bowel irrigation Source Type: news
New treatment strategy allows lower doses of toxic tuberculosis drug without compromising potency
While an effective treatment is available for combating multidrug-resistant tuberculosis, it carries serious side effects for patients. New research shows that lower doses of the toxic drug bedaquiline — given together with verapamil, a medication that’s used to treat various heart conditions — can lead to the same antibacterial effects as higher toxic doses of bedaquiline. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 30, 2014 Category: Science Source Type: news
New treatment strategy allows lower doses of toxic tuberculosis drug without compromising potency
(Johns Hopkins Medicine) While an effective treatment is available for combating multidrug-resistant tuberculosis, it carries serious side effects for patients. New research conducted at the Center for Tuberculosis Research at the Johns Hopkins University School of Medicine shows that lower doses of the toxic drug bedaquiline -- given together with verapamil, a medication that's used to treat various heart conditions -- can lead to the same antibacterial effects as higher toxic doses of bedaquiline. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 30, 2014 Category: Infectious Diseases Source Type: news
Verapamil Hope for Reversal of Type 1 DiabetesVerapamil Hope for Reversal of Type 1 Diabetes
A first-of-its kind trial in patients with type 1 diabetes will attempt to reverse the disease process by increasing beta-cell mass using a common blood-pressure-lowering pill. Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - November 6, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
