Myeloid-derived Trefoil Factor 2 (TFF2) controls epithelial regeneration at the mucosal interface
Immunology Interest Group Seminar Series Trefoil factor proteins, an enigmatic family of mucosal cytokines, are known to promote tissue repair. Despite being discovered decades ago, not much was known until recently about how Trefoil proteins work. Dr. Herbert ’ s laboratory has discovered that these proteins regulate immune responses in allergic asthma and hookworm infection, and that they trigger the regeneration of epithelial cells. De ’ Broski Herbert is an Associate Professor of Immunology at the University of Pennsylvania School of Veterinary Medicine. He received his B.S. in microbiology from Xavier University i...
Source: Videocast - All Events - March 13, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Vivian Pinn Symposium 2017
2nd Annual Vivian Pinn Symposium 2:00 – 2:05 Welcome and Opening Remarks Janine Austin Clayton, M.D., Associate Director for Research on Women ’ s Health, Director, Office of Research on Women ’ s Health, NIH 2:05 – 2:10 Remarks Vivian W. Pinn, M.D., Senior Scientist Emerita, Fogarty International Center Former Director, Office of Research on Women ’ s Health, NIH 2:10 – 2:20 The Director ’ s Award Theme: Nursing and caregiving 2:20 – 2:25 Setting the Stage and Speaker Introduction Monica Basco, PhD, Associate Director, Science Policy, Planning and Analysis 2:25 – 2:35 Title TBD Ana Langer, M.D...
Source: Videocast - All Events - March 2, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

DDM Seminar Series - Resilient and Ready: How to Thrive Through Challenge and Change
DDM Seminar Series The second installment of the FY2017 DDM Seminar Series. To receive credit for watching the LIVE Videocast, you need to register for the event in LMS on the morning of the event. Archived Videocast registration is also available in LMS approximately 10 days after the event. Videocast from Masur Auditorium, this second seminar features Valorie Burton, who will be sharing science-based means for overcoming setbacks, adapting to change, and ultimately thriving despite the challenges and complexities we encounter at work. Valorie Burton is the bestselling author of Why Not You, named by Success Magazine as o...
Source: Videocast - All Events - February 9, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Development of Targeted New Agents for Children with Cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Peter Adamson is Chair of the Children ’ s Oncology Group (COG), a National Cancer Institute (NCI) supported international consortium of more than 220 childhood centers that conducts clinical-translational research, including large-scale clinical trials, in children with cancer. Dr. Adamson is Board Certified in Pediatric Hematology/Oncology and in Clinical Pharmacology. He currently serves on the National Cancer Advisory Board (NCAB) and is an internationally recognized leader in pediatric cancer drug development. Prior to becoming Chair of the COG in 2011, Dr....
Source: Videocast - All Events - November 14, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Cytokine Signaling: Genes, Genomes and Drugs
Eleventh annual Philip S. Chen, Jr., Ph.D. Distinguished Lecture on Innovation and Technology Transfer John J. O'Shea graduated Phi Beta Kappa from St. Lawrence University with a Bachelor of Science degree, and then gained a Doctor of Medicine degree from the University of Cincinnati. He carried out a residency in Internal Medicine at the State University of New York Upstate Medical University and did subspecialty training at the National Institute of Allergy and Infectious Diseases, NIH. Dr. O ’ Shea has made fundamental discoveries related to the basic mechanisms underlying cytokine signal transduction, molecule...
Source: Videocast - All Events - October 4, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Transforming Pancreatic Cancer into an Immunological Disease
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Jaffee currently serves as Deputy Director for the Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins University (JHU), and Co-Director of the Immunology Program and Associate Director for Translational Sciences for SKCCC. She established the Cell and Gene Therapy Processing Facility (cGMP facility) at JHU. In 2007, she was appointed Deputy Director for the Institute for Translational and Clinical Research at JHU School of Medicine. She has also served as Chair of the Clinical Research Committee at SKCCC. Dr. Jaffee has served on a number of commit...
Source: Videocast - All Events - October 3, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Pancreatic Cancer Organoids for Biology and Medicine
NCI Center for Cancer Research Eminent Lecture Series David Tuveson is the Roy J. Zuckerberg Professor of Cancer Research, and Deputy Director of the cancer center at Cold Spring Harbor Laboratory (CSHL). Dr. Tuveson obtained a Bachelor ’ s degree in chemistry at M.I.T., followed by M.D. and Ph.D. degrees at Johns Hopkins University. Dr. Tuveson was a medical resident at Brigham and Women ’ s Hospital and a medical oncology fellow at Dana-Farber/Partners Cancer Care. During his post-doctoral years in Boston, Dr. Tuveson co-developed KIT inhibitors for gastrointestinal stromal tumors with Dr. George Demetri. Simultaneo...
Source: Videocast - All Events - September 12, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Oncogene Addiction
NCI Center for Cancer Research Eminent Lecture Dr. Felsher obtained a B.A. in Chemistry at the University of Chicago, a M.D. Ph.D. from the University of California, Los Angeles School of Medicine. He performed his graduate work in Molecular Biology/Immunology under Dr. Jonathan Braun. He trained in Internal Medicine at the Hospital of the University of Pennsylvania and Oncology at the University of California, San Francisco and his post-doctoral research under Dr. J. Michael Bishop. Dr. Felsher has been faculty at Stanford University for 16 years and performing both basic and translational cancer research and is the foun...
Source: Videocast - All Events - May 18, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

A Shared Program Underlying Early T Cell and Innate Lymphocyte Development.
Immunology Interest Group Avinash Bhandoola received a Ph.D. from the University of Pennsylvania in 1994, and did a postdoctoral fellowship with Dr. Alfred Singer at NCI focused on the rules underlying linage choice. He joined the faculty of the University of Pennsylvania in 2001, received tenure in 2007, and was promoted to full professor in 2012. His laboratory identified early precursors of T cells in the bone marrow and thymus, described the mechanisms used by precursor cells to migrate to the thymus, and studied transcription factors that imposed the T cell program. Recently, his work also implicated transcription fa...
Source: Videocast - All Events - April 28, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Long Non-coding RNAs and the Homeostasis of Innate Immune Cells
Presented by: Jorge Henao-Mejia, M.D., Ph.D.; Assistant Professor of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of MedicineCategory: ImmunologyAired date: 04/06/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - April 7, 2016 Category: Journals (General) Tags: Past Events Source Type: video

A daily period of unproductivity: Can we solve the mystery of sleep?
Presented by: Amita Sehgal, Ph.D., Investigator, Howard Hughes Medical Institute; Professor and Vice Chair, Department of Neuroscience, University of Pennsylvania; Director, Chronobiology Program at University of PennsylvaniaCategory: WALS - Wednesday Afternoon LecturesAired date: 04/06/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - April 7, 2016 Category: Journals (General) Tags: Past Events Source Type: video

Long Non-coding RNAs and the Homeostasis of Innate Immune Cells
Immunology Interest Group Jorge Henao-Mejia obtained his M.D. in 2005 from the University of Antioquia, Medellin, Colombia and his Ph.D. in 2009 from Indiana University, Indianapolis. He was a post-doctoral fellow with Richard Flavell at Yale University, where he studied the interactions between the immune system and metabolism in the context of health and obesity. Since summer 2014, he has been on the Faculty at the University of Pennsylvania. His current research aims to understand the role of the innate immune system in the development of metabolic syndrome, and to comprehend the metabolic pathways that are necessary ...
Source: Videocast - All Events - April 1, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Great Teachers: Career Development: Joys of Discovery
Presented by: Emma A. Meagher, MD Senior Associate Dean for Clinical Research, Perelman School of Medicine and Associate Vice Provost for Human Subjects Research, University of Pennsylvania, Philadelphia Category: Clinical Center Grand RoundsAired date: 03/09/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - March 10, 2016 Category: Journals (General) Tags: Past Events Source Type: video

How to Maintain Serum Antibody Titers?
Immunology Interest Group David Allman is an Associate Professor of Pathology and Laboratory Medicine in the Department of Pathology and Laboratory Medicine of the Perelman School of Medicine at the University of Pennsylvania. He described what are now called transitional B cells during his PhD. This work showed that B cell maturation and formation of the B cell repertoire is completed in peripheral lymphoid tissues rather than in the bone marrow. Later, working with Warren Pear, he established roles for Notch in T lineage commitment. Recently he has focused on antibody secreting plasma cells, and has discovered that T-c...
Source: Videocast - All Events - March 2, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Action and Traction at the Immunological Synapse
Presented by: Janis Burkhardt, Ph.D.; Professor of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine; and Evelyn & George Willing Endowed Chair in Pathology Research, Children’s Hospital of PhiladelphiaCategory: ImmunologyAired date: 01/20/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - January 21, 2016 Category: Journals (General) Tags: Past Events Source Type: video