Gastric outlet obstruction with prostaglandin E1 infusion in congenital diaphragmatic hernia
Prostaglandin E1 (PGE1) is used globally in neonatal medicine to maintain patency of the ductus arteriosus in duct-dependent congenital heart disease. Due to its non-selective pulmonary vasodilator effect and its role in offloading the pressure on the right ventricle via the ductus arteriosus, PGE1 has been increasingly used in the management of neonatal pulmonary hypertension, especially in those patients with congenital diaphragmatic hernia (CDH).1 2 Gastric outlet obstruction (GOO) has been described as a side effect of PGE1 in populations with congenital heart disease, most commonly secondary to hypertrophic pyloric st...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 17, 2023 Category: Perinatology & Neonatology Authors: Togo, A., Stewart, D., Moody, A., King, S., Armstrong, R. K. Tags: PostScript Source Type: research
Evaluating Risk Factors for Developing Allergic Reactions during Plasma Exchange using Fresh-frozen Plasma: A Single-center Retrospective Study
Conclusion Allergic reaction onset occurred approximately one hour after PEx initiation in the critical period. A serum Alb level ≥3.4 g/dL was identified as a risk factor for predicting allergic reactions. Patients with Alb levels ≥3.4 g/dL at the first PEx should be monitored for allergic reaction symptoms.PMID:36792201 | DOI:10.2169/internalmedicine.0507-22 (Source: Internal Medicine)
Source: Internal Medicine - February 15, 2023 Category: Internal Medicine Authors: Tetsuya Abe Togo Aoyama Yasuo Takeuchi Source Type: research
A field investigation of short-range dispersal by female simulium damnosum s.l
Acta Trop. 2023 Feb 11:106863. doi: 10.1016/j.actatropica.2023.106863. Online ahead of print.ABSTRACTFemale Simulium damnosum s.l. were caught at a site in a savannah zone beside the Mono River in Togo and at varying distances westwards perpendicular to it in an experiment to investigate short-range dispersal by the flies. The numbers of flies caught and the percentages that were parous decreased with increasing distance from the river, the latter suggesting that nulliparous flies disperse on average further than parous flies. The decreases were quantified using statistically significant multiple regressions involving dist...
Source: Acta Tropica - February 13, 2023 Category: Infectious Diseases Authors: J Frank Walsh Robert A Cheke Stephen Young Source Type: research
A field investigation of short-range dispersal by female simulium damnosum s.l
Acta Trop. 2023 Feb 11:106863. doi: 10.1016/j.actatropica.2023.106863. Online ahead of print.ABSTRACTFemale Simulium damnosum s.l. were caught at a site in a savannah zone beside the Mono River in Togo and at varying distances westwards perpendicular to it in an experiment to investigate short-range dispersal by the flies. The numbers of flies caught and the percentages that were parous decreased with increasing distance from the river, the latter suggesting that nulliparous flies disperse on average further than parous flies. The decreases were quantified using statistically significant multiple regressions involving dist...
Source: Acta Tropica - February 13, 2023 Category: Infectious Diseases Authors: J Frank Walsh Robert A Cheke Stephen Young Source Type: research
Structural Insight into Privileged Heterocycles as Anti-Trypanosoma cruzi and brucei Agents
Curr Top Med Chem. 2023 Feb 1. doi: 10.2174/1568026623666230201103843. Online ahead of print.ABSTRACTTrypanosomiasis is caused by parasitic protozoan trypanosomes in vertebrates. T. cruzi and T. brucei are causative agents of Chagas disease (CD) and Human African Trypanosomiasis (HAT), respectively. These life-threatening diseases are a serious threat to public health, with considerable incidence in sub-Saharan African and continental Latin America countries. Although WHO validated mitigated number of HAT cases in Togo (June 2020) and Cote d'Ivoire (December 2020), serious efforts need to be performed for the elimination o...
Source: Current Topics in Medicinal Chemistry - February 1, 2023 Category: Chemistry Authors: Jafar Abbasi Shiran Mina Ghanbari Elaheh Mohammadnejadi Nima Razzaghi-Asl Source Type: research
Structural Insight into Privileged Heterocycles as Anti-Trypanosoma cruzi and brucei Agents
Curr Top Med Chem. 2023 Feb 1. doi: 10.2174/1568026623666230201103843. Online ahead of print.ABSTRACTTrypanosomiasis is caused by parasitic protozoan trypanosomes in vertebrates. T. cruzi and T. brucei are causative agents of Chagas disease (CD) and Human African Trypanosomiasis (HAT), respectively. These life-threatening diseases are a serious threat to public health, with considerable incidence in sub-Saharan African and continental Latin America countries. Although WHO validated mitigated number of HAT cases in Togo (June 2020) and Cote d'Ivoire (December 2020), serious efforts need to be performed for the elimination o...
Source: Current Topics in Medicinal Chemistry - February 1, 2023 Category: Chemistry Authors: Jafar Abbasi Shiran Mina Ghanbari Elaheh Mohammadnejadi Nima Razzaghi-Asl Source Type: research
