Airway smooth muscle area to predict steroid responsiveness in COPD patients receiving triple therapy (HISTORIC): a randomised, placebo-controlled, double-blind, investigator-initiated trial
Conclusion
COPD patients with HASMC respond better to ICS than patients with LASMC, suggesting that this type of histological analysis may predict ICS responsiveness in COPD patients receiving triple therapy. (Source: European Respiratory Journal)
Source: European Respiratory Journal - July 20, 2023 Category: Respiratory Medicine Authors: Stolz, D., Papakonstantinou, E., Pascarella, M., Jahn, K., Siebeneichler, A., Darie, A. M., Herrmann, M. J., Strobel, W., Salina, A., Grize, L., Savic Prince, S., Tamm, M. Tags: COPD and smoking Original Articles: COPD Source Type: research
Single dose of budesonide/formoterol turbuhaler compared to salbutamol pMDI for speed of bronchodilator onset in asthma: a randomised cross-over trial
Conclusion
The results do not support the primary hypothesis of non-inferiority at the boundary of –0.06 L for the difference between budesonide/formoterol 200/6 µg compared with salbutamol 200 µg for FEV1 at 2 min, and could be consistent with inferiority with a p value of 0.07. For the secondary analysis of FEV1 measurements over time, the FEV1 was higher with salbutamol.
Trial registration number
Australian and New Zealand Clinical Trials Registry (ACTRN 12619001387112). (Source: Thorax)
Source: Thorax - July 13, 2023 Category: Respiratory Medicine Authors: Kearns, N., Williams, M., Bruce, P., Black, M., Kearns, C., Sparks, J., Braithwaite, I., Weatherall, M., Beasley, R. Tags: Thorax Asthma Source Type: research
Effects of omalizumab combined with budesonide formoterol on clinical efficacy, pulmonary function, immune function, and adverse reactions in children with moderate and severe allergic asthma
CONCLUSION: The combination of omalizumab with budesonide formoterol for treating moderate and severe allergic asthma in children demonstrated promising clinical efficacy and improved their pulmonary and immune functions, leading to more rational asthma control. The combined regimen demonstrated satisfactory clinical safety and deserved clinical promotion.PMID:37422796 | DOI:10.15586/aei.v51i4.926 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fuzhe Chen Lei Liang Fang Fang Chu Changlong Lu Chongyu Xu Source Type: research
Effect of budesonide formoterol combined with tiotropium bromide on pulmonary function and inflammatory factors in patients with asthma-COPD overlap syndrome
CONCLUSION: The combination of budesonide formoterol to tiotropium bromide in treating asthma-COPD overlap syndrome may significantly improve pulmonary function, endothelial function, and immune status of patients and encourage the recovery of serum lipid peroxidation injury; therefore, this may deserve widespread adoption and application.PMID:37422789 | DOI:10.15586/aei.v51i4.876 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Ting Jiang Pengfei Li Yang Wang Source Type: research
Effects of omalizumab combined with budesonide formoterol on clinical efficacy, pulmonary function, immune function, and adverse reactions in children with moderate and severe allergic asthma
CONCLUSION: The combination of omalizumab with budesonide formoterol for treating moderate and severe allergic asthma in children demonstrated promising clinical efficacy and improved their pulmonary and immune functions, leading to more rational asthma control. The combined regimen demonstrated satisfactory clinical safety and deserved clinical promotion.PMID:37422796 | DOI:10.15586/aei.v51i4.926 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fuzhe Chen Lei Liang Fang Fang Chu Changlong Lu Chongyu Xu Source Type: research
Effect of budesonide formoterol combined with tiotropium bromide on pulmonary function and inflammatory factors in patients with asthma-COPD overlap syndrome
CONCLUSION: The combination of budesonide formoterol to tiotropium bromide in treating asthma-COPD overlap syndrome may significantly improve pulmonary function, endothelial function, and immune status of patients and encourage the recovery of serum lipid peroxidation injury; therefore, this may deserve widespread adoption and application.PMID:37422789 | DOI:10.15586/aei.v51i4.876 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Ting Jiang Pengfei Li Yang Wang Source Type: research
Effects of omalizumab combined with budesonide formoterol on clinical efficacy, pulmonary function, immune function, and adverse reactions in children with moderate and severe allergic asthma
CONCLUSION: The combination of omalizumab with budesonide formoterol for treating moderate and severe allergic asthma in children demonstrated promising clinical efficacy and improved their pulmonary and immune functions, leading to more rational asthma control. The combined regimen demonstrated satisfactory clinical safety and deserved clinical promotion.PMID:37422796 | DOI:10.15586/aei.v51i4.926 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fuzhe Chen Lei Liang Fang Fang Chu Changlong Lu Chongyu Xu Source Type: research
Effect of budesonide formoterol combined with tiotropium bromide on pulmonary function and inflammatory factors in patients with asthma-COPD overlap syndrome
CONCLUSION: The combination of budesonide formoterol to tiotropium bromide in treating asthma-COPD overlap syndrome may significantly improve pulmonary function, endothelial function, and immune status of patients and encourage the recovery of serum lipid peroxidation injury; therefore, this may deserve widespread adoption and application.PMID:37422789 | DOI:10.15586/aei.v51i4.876 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Ting Jiang Pengfei Li Yang Wang Source Type: research
Effect of budesonide formoterol combined with tiotropium bromide on pulmonary function and inflammatory factors in patients with asthma-COPD overlap syndrome
CONCLUSION: The combination of budesonide formoterol to tiotropium bromide in treating asthma-COPD overlap syndrome may significantly improve pulmonary function, endothelial function, and immune status of patients and encourage the recovery of serum lipid peroxidation injury; therefore, this may deserve widespread adoption and application.PMID:37422789 | DOI:10.15586/aei.v51i4.876 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Ting Jiang Pengfei Li Yang Wang Source Type: research
Effect of budesonide formoterol combined with tiotropium bromide on pulmonary function and inflammatory factors in patients with asthma-COPD overlap syndrome
CONCLUSION: The combination of budesonide formoterol to tiotropium bromide in treating asthma-COPD overlap syndrome may significantly improve pulmonary function, endothelial function, and immune status of patients and encourage the recovery of serum lipid peroxidation injury; therefore, this may deserve widespread adoption and application.PMID:37422789 | DOI:10.15586/aei.v51i4.876 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Ting Jiang Pengfei Li Yang Wang Source Type: research
Effects of omalizumab combined with budesonide formoterol on clinical efficacy, pulmonary function, immune function, and adverse reactions in children with moderate and severe allergic asthma
CONCLUSION: The combination of omalizumab with budesonide formoterol for treating moderate and severe allergic asthma in children demonstrated promising clinical efficacy and improved their pulmonary and immune functions, leading to more rational asthma control. The combined regimen demonstrated satisfactory clinical safety and deserved clinical promotion.PMID:37422796 | DOI:10.15586/aei.v51i4.926 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fuzhe Chen Lei Liang Fang Fang Chu Changlong Lu Chongyu Xu Source Type: research
Effects of omalizumab combined with budesonide formoterol on clinical efficacy, pulmonary function, immune function, and adverse reactions in children with moderate and severe allergic asthma
CONCLUSION: The combination of omalizumab with budesonide formoterol for treating moderate and severe allergic asthma in children demonstrated promising clinical efficacy and improved their pulmonary and immune functions, leading to more rational asthma control. The combined regimen demonstrated satisfactory clinical safety and deserved clinical promotion.PMID:37422796 | DOI:10.15586/aei.v51i4.926 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fuzhe Chen Lei Liang Fang Fang Chu Changlong Lu Chongyu Xu Source Type: research
Effects of omalizumab combined with budesonide formoterol on clinical efficacy, pulmonary function, immune function, and adverse reactions in children with moderate and severe allergic asthma
CONCLUSION: The combination of omalizumab with budesonide formoterol for treating moderate and severe allergic asthma in children demonstrated promising clinical efficacy and improved their pulmonary and immune functions, leading to more rational asthma control. The combined regimen demonstrated satisfactory clinical safety and deserved clinical promotion.PMID:37422796 | DOI:10.15586/aei.v51i4.926 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fuzhe Chen Lei Liang Fang Fang Chu Changlong Lu Chongyu Xu Source Type: research
Effects of omalizumab combined with budesonide formoterol on clinical efficacy, pulmonary function, immune function, and adverse reactions in children with moderate and severe allergic asthma
CONCLUSION: The combination of omalizumab with budesonide formoterol for treating moderate and severe allergic asthma in children demonstrated promising clinical efficacy and improved their pulmonary and immune functions, leading to more rational asthma control. The combined regimen demonstrated satisfactory clinical safety and deserved clinical promotion.PMID:37422796 | DOI:10.15586/aei.v51i4.926 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fuzhe Chen Lei Liang Fang Fang Chu Changlong Lu Chongyu Xu Source Type: research
Effect of budesonide formoterol combined with tiotropium bromide on pulmonary function and inflammatory factors in patients with asthma-COPD overlap syndrome
CONCLUSION: The combination of budesonide formoterol to tiotropium bromide in treating asthma-COPD overlap syndrome may significantly improve pulmonary function, endothelial function, and immune status of patients and encourage the recovery of serum lipid peroxidation injury; therefore, this may deserve widespread adoption and application.PMID:37422789 | DOI:10.15586/aei.v51i4.876 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Ting Jiang Pengfei Li Yang Wang Source Type: research
