Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL Patients
Conditions: B-cell Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia, in Relapse; Refractory Acute Lymphoid Leukemia Interventions: Drug: CD19 CAR T-cell; Drug: CD22 CAR T cells; Procedure: hematopoietic stem-cell transplantation Sponsors: Beijing GoBroad Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials
HCMV Breakthrough Infections During Letermovir Prophylaxis
Conditions: Cytomegalovirus Infections; Cytomegalovirus Viremia; Hematopoietic Stem Cell Transplantation Interventions: Diagnostic Test: Determination of HCMV DNA in plasma after DNAse digestion.; Diagnostic Test: Determination of HCMV DNA in blood or plasma. Sponsors: Foundation IRCCS San Matteo Hospital; Ministero della Salute, Italy Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 1, 2024 Category: Research Source Type: clinical trials
Adding Venetoclax to the High-dose Chemotherapy Regimen Prior to Mismatche Allogeneic Stem Cell Transplant
Conditions: Acute Myeloid Leukemia; Myelodysplastic Syndromes Interventions: Drug: Venetoclax; Drug: Decitabine; Drug: Fludarabine; Drug: Busulfan; Radiation: Total Body Irradiation Sponsors: Northside Hospital, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials
Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors
Conditions: Hematopoietic Stem Cell Transplant Interventions: Behavioral: PATH Sponsors: Brigham and Women ' s Hospital; Dana-Farber Cancer Institute; Duke University; H. Lee Moffitt Cancer Center and Research Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Chaplain-Delivered Compassion Meditation to Improve Spiritual Care of Patients Receiving Stem Cell Transplantation
Conditions: Lymphoma; Multiple Myeloma Interventions: Procedure: Spiritual Therapy; Other: Best Practice Sponsors: Emory University; National Cancer Institute (NCI); National Center for Complementary and Integrative Health (NCCIH) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease?
Conditions: Safety Issues; Efficacy Interventions: Other: Mesenchymal Stem Cells; Other: Comparative placebo Sponsors: Centre Hospitalier Universitaire de Liege Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials
CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia
Conditions: T-Cell Acute Lymphocytic Leukemia; Acute Lymphoblastic Leukemia, in Relapse; Refractory Acute Lymphoblastic Leukemia Interventions: Drug: Autologous CD5 CAR T-cells; Drug: Previous stem-cell transplantation (SCT) donor-derived CD5 CAR T-cells; Drug: Newly matched donor-derived CD5 CAR T-cells Sponsors: Beijing GoBroad Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Conditions: GVHD,Acute; Acute Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders Interventions: Drug: ATG Combined with Tacrolimus and Mini Methotrexate Sponsors: University of Alabama at Birmingham Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials
Platelet Rich Plasma Combined With Human Umbilical Cord Mesenchymal Stem Cells for Stage 3 and 4 Stress Injury
Conditions: Pressure Injuries - Stage 3; Pressure Injuries - Stage 4 Interventions: Biological: Platelet-rich plasma (PRP) combined with human umbilical cord mesenchymal stem cells (huMSCs); Other: Control group Sponsors: Liaocheng People ' s Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatment
Conditions: Graft Versus Host Disease Interventions: Biological: Wharton ' s jelly mesenchymal stem cells (WJ-MSCs) Sponsors: Fundaci ón Oftalmológica de Santander Clínica Carlos Ardila Lulle; Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud - IDCBIS Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Exercise and Health Counseling in Pediatric Hematopoietic Stem Cell Transplantation
Conditions: Hematopoietic System--Cancer Interventions: Behavioral: Control Group (Active Comparator); Behavioral: Intervention Group Sponsors: Alejandro Lucia; Hospital Infantil Universitario Ni ño Jesús, Madrid, Spain; Hospital General Universitario Gregorio Marañon; Hospital Universitario La Paz; Hospital Universitario 12 de Octubre Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Acute Myeloid Leukemia and Markers of Leukemia Stem Cells (CLL1 and CD45RA)
Conditions: Acute Myeloid Leukemia Interventions: Diagnostic Test: Quantification of blood cells positive for CLL1 and CD45RA surface markers by flow cytometry Sponsors: Suhu Liu Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation
Conditions: Allogeneic Stem Cell Transplantation Interventions: Drug: ASTX727; Drug: Donor Lymphocyte Infusion Sponsors: M.D. Anderson Cancer Center; Astex Pharmaceuticals, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies
Conditions: Acute Graft-versus-host Disease Interventions: Procedure: Time of stem cell infusion Sponsors: Anhui Provincial Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
Effect of Stem Cell Infusion Time on aGVHD in Patients With Nonmalignant Hematologic Diseases
Conditions: Acute Graft-versus-host Disease Interventions: Procedure: Time of stem cell infusion Sponsors: Anhui Provincial Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
