Non-Responsive Diabetic Macular Edema and Spironolactone
Condition: Diabetic Maculopathy Intervention: Drug: Spironolactone 50 mg Sponsor: Wake Forest University Health Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 21, 2021 Category: Research Source Type: clinical trials
Randomized clinical trial to compare the efficacy of ivermectin versus placebo to negativize nasopharyngeal PCR in patients with early COVID-19 in Peru (SAINT-Peru): a structured summary of a study protocol for randomized controlled trial
AbstractObjectivesThe primary objective is to determine the effect of a daily dose of ivermectin administered in three consecutive days to non-severe COVID-19 patients with no more than 96 hours of symptoms, on the detection of SARS-CoV-2 RNA by PCR from nasopharyngeal swabs at day seven post-treatment initiation.The secondary objectives are:To assess the efficacy of ivermectin to reduce the SARS-CoV-2 viral load in the nasopharyngeal swab on days 4, 7, 14 and 21 post-treatment initiationTo assess the efficacy of ivermectin on the improvement of symptomsTo assess the proportion of seroconversions at day 21To assess the saf...
Source: Trials - April 9, 2021 Category: Research Source Type: clinical trials
Spironolactone and Dexamethasone in Patients Hospitalized With COVID-19
Conditions: Coronavirus Infection; Pneumonia, Viral Interventions: Drug: Spironolactone + Dexamethasone; Drug: Standard-of-care SARS-CoV-2 treatment Sponsor: Chita State Regional Clinical Hospital Number 1 Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 1, 2021 Category: Research Source Type: clinical trials