Quadruple Immunotherapy for Neuroblastoma
Condition:   Neuroblastoma Recurrent Interventions:   Biological: Natural killer cell;   Drug: Dinutuximab beta;   Drug: Interleukin-2;   Drug: Granulocyte-Macrophage Colony-Stimulating Factor;   Drug: Spironolactone Sponsors:   Hong Kong Children's Hospital;   The University of Hong Kong Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2023 Category: Research Source Type: clinical trials

Effects of half-dose spiomet treatment in girls with early puberty and accelerated bone maturation: a multicenter, randomized, placebo-controlled study protocol
DiscussionThe present study, if successful, may provide a first proof of the concept that the rapid maturation of girls with an upward mismatch between pre- and post-natal weight gain can be slowed down with a fixed low-dose combination of old and safe generics jointly targeting a reduction of ectopic fat without necessarily lowering body weight.Trial registrationEudraCT 2021-006766-21. Registered on May 30, 2022. (Source: Trials)
Source: Trials - January 24, 2023 Category: Research Source Type: clinical trials