Longitudinal MRI in the context of in utero surgery for open spina bifida: A descriptive study
ConclusionsThere was timely access to supervised MRI for OSB fetal surgery assessment. However, the provision of images of the fetal brain and spine in sufficient orthogonal planes, which are required for determining eligibility and to determine the reversal of hindbrain herniation after fetal surgery, were less frequently acquired. Our evidence suggests the need for specific guidance in relation to fetal MRI for OSB. We propose an example guidance for MRI acquisition and reporting. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - November 21, 2023 Category: OBGYN Authors: Nada Mufti,
Michael Aertsen,
Dominic Thomson,
Phillippe De Vloo,
Philippe Demaerel,
Jan Deprest,
Andrew Melbourne,
Anna L. David,
the GIFT‐Surg Imaging Working Group,
David Atkinson,
Foteini Emmanouella Bredaki,
Joanna Chappell,
Luc De Cat Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Effect of Bladder Volume and Compliance on Ultrasonographic Measurement of Bladder Wall Thickness in Children with Neurogenic Bladder Dysfunction
Spina bifida is the most common cause of neurogenic bladder dysfunction in children. Measurement of bladder wall thickness (BWT) is non-invasive, low-cost, and may be complementary to urodynamics in demonstrating bladder condition. It is still unknown the wall thickness response to volume change in bladders with different compliance states. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 17, 2023 Category: Urology & Nephrology Authors: Sabriye G ülçin Bozbeyoğlu, Furkan Ersoy, Arzu Canmemiş, Narmina Khanmammadova, Şeyhmus Kerem Özel Source Type: research
Revisiting the MOMS criteria for prenatal repair of spina bifida: should upper limit of gestational age and anatomical level be maintained?
CONCLUSIONS: The 4-week interval between the first evaluation and the "late" fetal surgical repair does not significantly change motor function, suggesting that later repair > 26 weeks does not have a negative impact on motor outcome. The preoperative neuromotor functional assessment via ultrasound was better predictive of postnatal motor function as compared to the anatomical level of the lesion in cases undergoing prenatal repair of open spina bifida and should be included in preoperative counseling. This article is protected by copyright. All rights reserved.PMID:37970655 | DOI:10.1002/uog.27536 (Source: The Ultrasou...
Source: The Ultrasound Review of Obstetrics and Gynecology - November 16, 2023 Category: Radiology Authors: L Trigo R H Chmait A Llanes G Catissi E Eixarch A Van Speybroeck D Lapa Source Type: research
Revisiting the MOMS criteria for prenatal repair of spina bifida: should upper limit of gestational age and anatomical level be maintained?
CONCLUSIONS: The 4-week interval between the first evaluation and the "late" fetal surgical repair does not significantly change motor function, suggesting that later repair > 26 weeks does not have a negative impact on motor outcome. The preoperative neuromotor functional assessment via ultrasound was better predictive of postnatal motor function as compared to the anatomical level of the lesion in cases undergoing prenatal repair of open spina bifida and should be included in preoperative counseling. This article is protected by copyright. All rights reserved.PMID:37970655 | DOI:10.1002/uog.27536 (Source: The Ultrasou...
Source: The Ultrasound Review of Obstetrics and Gynecology - November 16, 2023 Category: Radiology Authors: L Trigo R H Chmait A Llanes G Catissi E Eixarch A Van Speybroeck D Lapa Source Type: research
Revisiting the MOMS criteria for prenatal repair of spina bifida: should upper limit of gestational age and anatomical level be maintained?
CONCLUSIONS: The 4-week interval between the first evaluation and the "late" fetal surgical repair does not significantly change motor function, suggesting that later repair > 26 weeks does not have a negative impact on motor outcome. The preoperative neuromotor functional assessment via ultrasound was better predictive of postnatal motor function as compared to the anatomical level of the lesion in cases undergoing prenatal repair of open spina bifida and should be included in preoperative counseling. This article is protected by copyright. All rights reserved.PMID:37970655 | DOI:10.1002/uog.27536 (Source: The Ultrasou...
Source: The Ultrasound Review of Obstetrics and Gynecology - November 16, 2023 Category: Radiology Authors: L Trigo R H Chmait A Llanes G Catissi E Eixarch A Van Speybroeck D Lapa Source Type: research
Revisiting the MOMS criteria for prenatal repair of spina bifida: should upper limit of gestational age and anatomical level be maintained?
CONCLUSIONS: The 4-week interval between the first evaluation and the "late" fetal surgical repair does not significantly change motor function, suggesting that later repair > 26 weeks does not have a negative impact on motor outcome. The preoperative neuromotor functional assessment via ultrasound was better predictive of postnatal motor function as compared to the anatomical level of the lesion in cases undergoing prenatal repair of open spina bifida and should be included in preoperative counseling. This article is protected by copyright. All rights reserved.PMID:37970655 | DOI:10.1002/uog.27536 (Source: The Ultrasou...
Source: The Ultrasound Review of Obstetrics and Gynecology - November 16, 2023 Category: Radiology Authors: L Trigo R H Chmait A Llanes G Catissi E Eixarch A Van Speybroeck D Lapa Source Type: research
Birth prevalence and risk factors of neural tube defects in Ethiopia: a systematic review and meta-analysis
Conclusion
The prevalence of NTDs in Ethiopia is seven times as high as in other Western countries where prevention measures are put in place. Heredity, maternal and environmental factors are associated with a high prevalence of NTDs. Mandatory fortification of staple food with folic acid should be taken as a priority intervention to curb the burden of NTDs. To smoothen and overlook the pace of implementation of mass fortification, screening, and monitoring surveillance systems should be in place along with awareness-raising measures.
PROSPERO registration number
CRD42023413490. (Source: BMJ Open)
Source: BMJ Open - November 7, 2023 Category: General Medicine Authors: Tesfay, N., Hailu, G., Habtetsion, M., Woldeyohannes, F. Tags: Open access, Neurology Source Type: research
Stratification of Neurogenic Bladder Risk in Spina Bifida Using the Urinary Peptidome
Am J Physiol Renal Physiol. 2023 Nov 2. doi: 10.1152/ajprenal.00267.2023. Online ahead of print.ABSTRACTNeurogenic bladder poses a major morbidity in children with Spina Bifida (SB) and videourodynamic studies (VUDS) are used to stratify this risk. This small-scale pilot study utilized current mass-spectrometry-based proteomic approaches to identify peptides or proteins in urine that may differentiate children at high-risk of developing renal complications from a neurogenic bladder. Twenty-two urine samples of which 9 had high bladder pressure storage that put the upper urinary tract at risk, while 13 with a lower risk for...
Source: Am J Physiol Renal P... - November 2, 2023 Category: Urology & Nephrology Authors: Hossein Fazelinia Hua Ding Deanne Taylor Lynn Spruce Jennifer Roof Dana Weiss Joanna Fesi Harry Ischiropoulos Stephen Zderic Source Type: research
Stratification of Neurogenic Bladder Risk in Spina Bifida Using the Urinary Peptidome
Am J Physiol Renal Physiol. 2023 Nov 2. doi: 10.1152/ajprenal.00267.2023. Online ahead of print.ABSTRACTNeurogenic bladder poses a major morbidity in children with Spina Bifida (SB) and videourodynamic studies (VUDS) are used to stratify this risk. This small-scale pilot study utilized current mass-spectrometry-based proteomic approaches to identify peptides or proteins in urine that may differentiate children at high-risk of developing renal complications from a neurogenic bladder. Twenty-two urine samples of which 9 had high bladder pressure storage that put the upper urinary tract at risk, while 13 with a lower risk for...
Source: American Journal of Physiology. Renal Physiology - November 2, 2023 Category: Physiology Authors: Hossein Fazelinia Hua Ding Deanne Taylor Lynn Spruce Jennifer Roof Dana Weiss Joanna Fesi Harry Ischiropoulos Stephen Zderic Source Type: research
Stratification of Neurogenic Bladder Risk in Spina Bifida Using the Urinary Peptidome
Am J Physiol Renal Physiol. 2023 Nov 2. doi: 10.1152/ajprenal.00267.2023. Online ahead of print.ABSTRACTNeurogenic bladder poses a major morbidity in children with Spina Bifida (SB) and videourodynamic studies (VUDS) are used to stratify this risk. This small-scale pilot study utilized current mass-spectrometry-based proteomic approaches to identify peptides or proteins in urine that may differentiate children at high-risk of developing renal complications from a neurogenic bladder. Twenty-two urine samples of which 9 had high bladder pressure storage that put the upper urinary tract at risk, while 13 with a lower risk for...
Source: Am J Physiol Renal P... - November 2, 2023 Category: Urology & Nephrology Authors: Hossein Fazelinia Hua Ding Deanne Taylor Lynn Spruce Jennifer Roof Dana Weiss Joanna Fesi Harry Ischiropoulos Stephen Zderic Source Type: research
Stratification of Neurogenic Bladder Risk in Spina Bifida Using the Urinary Peptidome
Am J Physiol Renal Physiol. 2023 Nov 2. doi: 10.1152/ajprenal.00267.2023. Online ahead of print.ABSTRACTNeurogenic bladder poses a major morbidity in children with Spina Bifida (SB) and videourodynamic studies (VUDS) are used to stratify this risk. This small-scale pilot study utilized current mass-spectrometry-based proteomic approaches to identify peptides or proteins in urine that may differentiate children at high-risk of developing renal complications from a neurogenic bladder. Twenty-two urine samples of which 9 had high bladder pressure storage that put the upper urinary tract at risk, while 13 with a lower risk for...
Source: American Journal of Physiology. Renal Physiology - November 2, 2023 Category: Physiology Authors: Hossein Fazelinia Hua Ding Deanne Taylor Lynn Spruce Jennifer Roof Dana Weiss Joanna Fesi Harry Ischiropoulos Stephen Zderic Source Type: research
Stratification of Neurogenic Bladder Risk in Spina Bifida Using the Urinary Peptidome
Am J Physiol Renal Physiol. 2023 Nov 2. doi: 10.1152/ajprenal.00267.2023. Online ahead of print.ABSTRACTNeurogenic bladder poses a major morbidity in children with Spina Bifida (SB) and videourodynamic studies (VUDS) are used to stratify this risk. This small-scale pilot study utilized current mass-spectrometry-based proteomic approaches to identify peptides or proteins in urine that may differentiate children at high-risk of developing renal complications from a neurogenic bladder. Twenty-two urine samples of which 9 had high bladder pressure storage that put the upper urinary tract at risk, while 13 with a lower risk for...
Source: Am J Physiol Renal P... - November 2, 2023 Category: Urology & Nephrology Authors: Hossein Fazelinia Hua Ding Deanne Taylor Lynn Spruce Jennifer Roof Dana Weiss Joanna Fesi Harry Ischiropoulos Stephen Zderic Source Type: research
Stratification of Neurogenic Bladder Risk in Spina Bifida Using the Urinary Peptidome
Am J Physiol Renal Physiol. 2023 Nov 2. doi: 10.1152/ajprenal.00267.2023. Online ahead of print.ABSTRACTNeurogenic bladder poses a major morbidity in children with Spina Bifida (SB) and videourodynamic studies (VUDS) are used to stratify this risk. This small-scale pilot study utilized current mass-spectrometry-based proteomic approaches to identify peptides or proteins in urine that may differentiate children at high-risk of developing renal complications from a neurogenic bladder. Twenty-two urine samples of which 9 had high bladder pressure storage that put the upper urinary tract at risk, while 13 with a lower risk for...
Source: American Journal of Physiology. Renal Physiology - November 2, 2023 Category: Physiology Authors: Hossein Fazelinia Hua Ding Deanne Taylor Lynn Spruce Jennifer Roof Dana Weiss Joanna Fesi Harry Ischiropoulos Stephen Zderic Source Type: research
Stratification of Neurogenic Bladder Risk in Spina Bifida Using the Urinary Peptidome
Am J Physiol Renal Physiol. 2023 Nov 2. doi: 10.1152/ajprenal.00267.2023. Online ahead of print.ABSTRACTNeurogenic bladder poses a major morbidity in children with Spina Bifida (SB) and videourodynamic studies (VUDS) are used to stratify this risk. This small-scale pilot study utilized current mass-spectrometry-based proteomic approaches to identify peptides or proteins in urine that may differentiate children at high-risk of developing renal complications from a neurogenic bladder. Twenty-two urine samples of which 9 had high bladder pressure storage that put the upper urinary tract at risk, while 13 with a lower risk for...
Source: Am J Physiol Renal P... - November 2, 2023 Category: Urology & Nephrology Authors: Hossein Fazelinia Hua Ding Deanne Taylor Lynn Spruce Jennifer Roof Dana Weiss Joanna Fesi Harry Ischiropoulos Stephen Zderic Source Type: research
