PD-1 Inhibitor Combined With Radiotherapy for Elderly ESCC
Conditions: Esophageal Squamous Cell Carcinoma Interventions: Drug: PD-1 inhibitor 200mg per three to four weeks, for one year Sponsors: Affiliated Hospital of Nantong University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials

HAIC Combined Sintilimab for Liver Metastasis From Esophageal Squamous Cell Carcinoma
Conditions: Hepatic Arterial Infusion Chemotherapy; Liver Metastases; Esophageal Squamous Cell Carcinoma Interventions: Drug: HAIC combined with intravenous PD-1 Sponsors: Peking University Cancer Hospital& Institute; Innovent Biologics (Suzhou) Co. Ltd. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials

Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy
Conditions: Head and Neck Cancer; Head and Neck Squamous Cell Carcinoma; Head and Neck Carcinoma Interventions: Radiation: Spot Delete Sponsors: Thompson Cancer Survival Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials

Managing Distress in Malignant Brain Cancer - Ph II Randomized Crontrolled Trial
Conditions: Brain Tumor; Brain Metastases; Brain Cancer; Metastatic Lung Cancer; Metastatic Breast Cancer; Metastatic Melanoma; Metastatic Colon Cancer; Metastatic Kidney Cancer Interventions: Behavioral: CALM; Behavioral: Treatment as usual Sponsors: Virginia Commonwealth University; United States Department of Defense Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 22, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Adebrelimab Plus Chemotherapy for Resectable ESCC: a Single Arm, Prospective Phase 2 Clinical Trial
Conditions: Esophageal Squamous Cell Carcinoma Interventions: Drug: Immunotherapy: Adebrelimab; Drug: chemotherapy: carboplatin plus nab-paclitaxel Sponsors: Shanghai Chest Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 20, 2023 Category: Research Source Type: clinical trials

Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer
Conditions: Esophageal Squamous Cell Carcinoma; Unresectable Locally Advanced Esophageal Cancer Interventions: Drug: PD-1inhibitor; Drug: nab-paclitaxel + cisplatin; Radiation: Radiotherapy Sponsors: Shanghai Chest Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 18, 2023 Category: Research Source Type: clinical trials

Validity of Viome's Oral/Throat Cancer Test
Conditions: Oral and Throat Cancer; Oropharyngeal Squamous Cell Carcinoma; Oral Squamous Cell Carcinoma Interventions: Device: Oral/Throat cancer test Sponsors: Viome Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 18, 2023 Category: Research Source Type: clinical trials

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Conditions: Advanced Solid Tumor; Melanoma; Head and Neck Cancer; Gastric Cancer Interventions: Drug: HER3-DXd Sponsors: Daiichi Sankyo, Inc.; Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC
Conditions: Head and Neck Squamous Cell Carcinoma Interventions: Drug: Anti-PD-1 monoclonal antibody; Other: Postoperative CCRT Sponsors: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Advanced First-line Treatment of Short-term Postoperative Progression of Head and Neck Squamous Cell Carcinoma
Conditions: Head and Neck Squamous Cell Carcinoma Interventions: Drug: Camrelizumab; Drug: Cisplatin; Drug: Carboplatin; Drug: Lobaplatin; Drug: Nedaplatin; Radiation: Radiotherapy Sponsors: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Moderna and Merck Announce mRNA-4157 (V940) in Combination with Keytruda ® (pembrolizumab) Demonstrated Continued Improvement in Recurrence-Free Survival and Distant Metastasis-Free Survival in Patients with High-Risk Stage III/IV Melanoma Following Complete Resection Versus KEYTRUDA At Three Years
At a median planned follow-up of approximately three years, mRNA-4157 (V940) in combination with KEYTRUDA reduced the risk of recurrence or death by 49% (HR=0.510 [95% CI, 0.288-0.906]; one-sided nominal p=0.0095) and the risk of distant... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - December 14, 2023 Category: Pharmaceuticals Source Type: clinical trials

Mind Over Matter for Black and African American Women: A Single Arm Trial Examining Feasibility and Acceptability of a Supportive Intervention
Conditions: Cancer; Breast Cancer; Brain Cancer; Central Nervous System Cancer; Colorectal Cancer; Esophageal Cancer; Gynecologic Cancer; Head and Neck Cancer; Gastrointestinal Cancer; Genitourinary Cancer; Melanoma; Blood Cancer; Lung Cancer; Acceptance and Commitment Therapy; Mind-Body Therapies; Psychosocial Intervention Interventions: Other: Mind Over Matter (MOM) Sponsors: Inova Health Care Services; Howard University; University of Louisville; University of Houston; Massey Cancer Center; Tigerlily Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials

Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study
Conditions: Tongue Neoplasms Interventions: Procedure: removal of primary tumor, neck dissection Sponsors: Cairo University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials

Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms
Conditions: Oesophageal Squamous Cell Carcinoma; Oesophageal Cancer Interventions: Other: Exhaled breath sampling Sponsors: Imperial College London; Imperial College Healthcare NHS Trust Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery
Conditions: Skin Cancer; Skin Carcinoma Interventions: Other: Lavender essential oil; Other: Water Sponsors: Case Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials