DM / DNB Cardiology Entrance New Test Series 2
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Source: Cardiophile MD - July 2, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs

PhRMA Members Invested $58.8 Billion in R&D in 2015
In 2015, PhRMA member companies invested $58.8 billion in research and development, up 10.3% from 2014. The new R&D data is based on findings from the 2016 PhRMA annual member survey released in the 2016 Biopharmaceutical Research Industry Profile and the corresponding industry chart pack, Biopharmaceuticals in Perspective, which highlighted the wide-reaching impact of PhRMA member companies on the economy and biopharmaceutical innovation. In the United States, the biopharmaceutical industry is a driver of economic growth and global competitiveness, and is the most research-intensive sector of the economy. The biopharmac...
Source: Policy and Medicine - June 16, 2016 Category: American Health Authors: Thomas Sullivan - Policy & Medicine Writing Staff Source Type: blogs

DM / DNB Cardiology Entrance Mock Test 26
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Source: Cardiophile MD - May 10, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs

Nephrogenic systemic sclerosis – Cardiology MCQ
Potential method/s to reduce the risk of nephrogenic systemic sclerosis after magnetic resonance imaging: a) Limiting the dose of gadolinium based contrast agent to less than 0.1 mmol/Kg body weight b) Dialysing them quickly after contrast administration c) Delaying contrast administration till recovery of renal function in those with acute renal failure d) All of the above Correct answer: d) All of the above In addition to these, avoiding non linear gadolinium based contrast agents in those with renal failure, more so when there are pro inflammatory conditions associated is also useful. Reference Zou Z et al. Nephrogen...
Source: Cardiophile MD - May 7, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiac Magnetic Resonance imaging Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

PNAS Paper By Prominent Cardiologist And Dean Retracted
A 2002 PNAS paper has been retracted by its authors, including senior author Pascal Goldschmidt, a prominent cardiologist and Dean of the University of Miami School of Medicine. News of the retraction was reported by Retraction Watch on Tuesday. The paper, “Deficient Smad7 expression: A putative molecular defect in scleroderma,”has been cited 198 times, Retraction Watch reported. Here is...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - April 6, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Goldschmidt Retraction Watch retractions scientific misconduct Source Type: blogs

Medical mistakes happen. It’s what doesn’t follow that is unforgivable.
38 states currently have an apology act. This means that if doctors feel they owe a patient an apology, they may provide one without any ramifications, if future legal actions are taken by the patient/patient’s family. In 2006, I spent 218 days in the hospital after the healthy birth of my daughter. My chronic autoimmune disease, scleroderma, masked certain signs of preeclampsia, which went undiagnosed. This led to a massive infection that ultimately resulted in eight major surgeries, two tracheotomies, ICU psychosis, sepsis, extreme deconditioning from the neck down, multiple interventional radiology drains, feeding tub...
Source: Kevin, M.D. - Medical Weblog - March 5, 2016 Category: Journals (General) Authors: Tags: Patient Hospital Malpractice Source Type: blogs

Wheat Belly: Self-Directed Health?
Director chair, film slate and load horn. Here’s a proposal for you: If, by following the Wheat Belly lifestyle, a long list of conditions are reduced or reversed at no risk, almost no cost, reversing even chronic and potentially fatal conditions . . . does that mean that the notion of self-directed health might be on the horizon, i.e., putting control over health back in our own hands? I think it does. No, we will never implant our own defibrillators or take out our own gallbladders. But so many chronic health conditions afflicting modern humans recede that I believe that it is entirely reasonable to start talking a...
Source: Wheat Belly Blog - February 16, 2016 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle arthritis autoimmune diabetes eating disorder gluten grains Inflammation joint Weight Loss Source Type: blogs

Funtabulously Frivolous Friday Five 120
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia…introducing Funtabulously Frivolous Friday Five 120 Question 1 What rheumatological condition does Rembrandt’s Scholar have? + Reveal the Funtabulous Answer expand(document.getElementById('ddet1210722826'));expand(document.getElementById('ddetlink1210722826')) Scleroderma He has a pinched nose, tight mouth, pale face with a malar flush, his hands are puffy and the joints on his right thumbs are swollen. Could this be Scleroderma? [Reference] Question 2 When Rac...
Source: Life in the Fast Lane - October 9, 2015 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five collapse dentist FFFF hands Kluver-bucy syndrome melanoma pleural collapse rachmaninoff rachmaninov Rembrandt scleroderma TB teeth temporal lobe Source Type: blogs

Autoimmunity as a Possible Side-Effect of Cancer Immunity
It has long been hypothesized that there is a link between autoimmune conditions and the immune response to cancer, and this article covers some of the high points. Autoimmune conditions are a set of complicated failure modes in a very complex system, in which the immune system attacks the patient's own tissues. They are perhaps the least well understood diseases, and this is reflected in the poor state of treatments for autoimmunity: no cures, and the best that can be done for patients is to dampen the overall immune response. Any path forward that grants additional insight into the early development of autoimmunity is we...
Source: Fight Aging! - September 3, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

LITFL Review 184
Welcome to the 184th LITFL Review. Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM. The Most Fair Dinkum Ripper Beauts of the Week Here’s an awesome new echo resource from the Nepean Hospital ICU in Penrith, NSW, Australia, containing basic and advanced physics and scanning resources. [SO]   The Best of #FOAMed Emergency Medicine Boring EM reviews the relevance of IN...
Source: Life in the Fast Lane - May 31, 2015 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs

Top stories in health and medicine, May 25, 2015
From MedPage Today: Time to Retire Lithotripsy for Kidney Stones? More than 30 years ago, extracorporeal shock wave lithotripsy (ESWL) had a highly anticipated, much-ballyhooed introduction as a nonsurgical therapy for kidney stones. Obviating the need to cut the skin or insert a device into the body, ESWL would use acoustic shock waves to pulverize stones into dust that would be washed out of the kidneys. Senate Committee Mulls Medicare Hospital Observation Stays. Hospital observation stays for Medicare patients can be problematic, but finding solutions is also tricky. Sildenafil May Help Heal Scleroderma Ulcers. Silden...
Source: Kevin, M.D. - Medical Weblog - May 25, 2015 Category: Journals (General) Authors: Tags: News Nephrology Pulmonology Source Type: blogs

Top stories in health and medicine, November 26, 2014
From MedPage Today: USPSTF: Routine Vitamin D Screening Unsupported. There is not enough evidence that vitamin D screening is beneficial in routine practice and therefore it can’t be recommended, according to the U.S. Preventive Services Task Force. SLE Patients See Good Outcomes in Blood Cancers. Risk of hematologic malignancy may be increased in patients with systemic lupus erythematosus compared with the general population, but outcomes with these cancers are about the same. Long-term Benefit With Stem-Cell Transplant in Scleroderma. Patients with rapidly progressing systemic sclerosis (SSc) showed sustained ben...
Source: Kevin, M.D. - Medical Weblog - November 26, 2014 Category: Journals (General) Authors: Tags: News Cancer Endocrinology Rheumatology Source Type: blogs

Top stories in health and medicine, October 13, 2014
From MedPage Today: Cashing in on Ebola. What was your reaction when you first realized that Ebola was killing thousands of people in Africa and would probably come ashore in America at some point? Sympathy? Worry? Scientific curiosity? An urge to hop the first plane to Monrovia? Ebola: Body Fluids Carry the Risk. The mantra of Ebola experts is that the disease is transmitted through direct contact with patient body fluids that contain the virus. But which fluids? And are they all equally risky? Joints Tell the Future in Scleroderma. Easily assessed clinical signs of joint and tendon involvement early in the course of sy...
Source: Kevin, M.D. - Medical Weblog - October 13, 2014 Category: Journals (General) Authors: Tags: News Infectious disease Rheumatology Source Type: blogs

Carbon dioxide angiography
(CO2 angiography) is resorted to in cases of renal failure. Iodinated contrast has the risk of contrast induced acute kidney injury, more so in those with pre-existing renal insufficiency. Earlier those with renal issues were considered for magnetic resonance angiography which was also called dyeless angiography as blood vessels can be visualized with the contrast obtained from moving hydrogen nuclei in water, an important constituent of blood. But for better visualization, gadolinium based contrasts are often used in magnetic resonance angiography. Gadolinium based contrasts have been associated with nephrogenic systemic...
Source: Cardiophile MD - August 30, 2014 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin, FRCP London Tags: Angiography and Interventions Source Type: blogs

MKSAP: 51-year-old woman with diarrhea and bloating
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 51-year-old woman is evaluated for a 6-month history of diarrhea and bloating. She reports four to six loose stools per day, with occasional nocturnal stools. She has had a few episodes of incontinence secondary to urgency. She has not had melena or hematochezia but notes an occasional oily appearance to the stool. She has lost 6.8 kg (15.0 lb) during this time period. Results of a colonoscopy 1 year ago were normal. She has not had recent travel, antibiotic use, or medication changes. She does not think consu...
Source: Kevin, M.D. - Medical Weblog - May 31, 2014 Category: Journals (General) Authors: Tags: Conditions GI Source Type: blogs