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Photosynthesis of silver nanoparticles embedded paper for sensing mercury presence in environmental water
Chemosphere. 2023 Apr 5:138610. doi: 10.1016/j.chemosphere.2023.138610. Online ahead of print.ABSTRACTHeavy metals released by anthropogenic activities are extremely toxic to animals and plants due to their bioaccumulative and persistent environmental presence. In the current study, silver nanoparticles (AgNPs) were synthesized utilizing eco-friendly processes, and their potential in colorimetric Hg2+ ion sensing in environmental samples was examined. An aqueous extract of Hemidesmus indicus root (Sarsaparilla Root, ISR) rapidly converts silver ions into AgNPs within 5 min of exposure to sunlight. Transmission electron mic...
Source: Chemosphere - April 7, 2023 Category: Chemistry Authors: Dharshini Karnan Singaravelu T Yokesh Mariappan Mariappan Fuad Ameen M Amirul Islam Anbazhagan Veerappan Source Type: research

Hemidesmus indicus L. Br.: critical assessment of in vitro biotechnological advancements and perspectives.
Abstract Hemidesmus indicus (L.) R. Br. ex Schult., commonly known as Indian sarsaparilla or Anantamul, is an ethnopharmacologically important medicinal plant from the family Apocynaceae. Biosynthesis of an array of bioactive compounds such as methoxybenzaldehydes and their derivatives has been accountable for its intensive medicinal attributes. Low seed setting, over-exploitation from natural habitat and a need for selection and preservation of elite germplasms yielding higher levels of bioactive compounds have led researchers to enquire the standardization of micropropagation techniques and quantitative ...
Source: Applied Microbiology and Biotechnology - September 9, 2020 Category: Microbiology Authors: Nandy S, Singh J, Pandey DK, Dey A Tags: Appl Microbiol Biotechnol Source Type: research

Correction to: Indian sarsaparilla, Hemidesmus indicus (L.) R. Br. ex Schult: tissue culture studies.
Abstract Following publication of the original article (Kher et al. 2020), the authors identified following mistake in the author affiliation. PMID: 32827048 [PubMed - as supplied by publisher] (Source: Applied Microbiology and Biotechnology)
Source: Applied Microbiology and Biotechnology - August 21, 2020 Category: Microbiology Authors: Kher MM, Shekhawat MS, Nataraj M, Teixeira da Silva JA Tags: Appl Microbiol Biotechnol Source Type: research

Indian sarsaparilla, Hemidesmus indicus (L.) R. Br. ex Schult: tissue culture studies.
Abstract Hemidesmus indicus (L.) R. Br. ex Schult is commonly known as anantmul or Indian sarsaparilla. The roots of this plant, which display a wide range of medicinal, biological, and phytopharmaceutical properties, are used in the pharmaceutical and food industries. Conventionally, the plant is propagated by seed germination or vegetatively, but the efficacy of traditional methods has some limitations: plants derived from seed germination are prone to seed-borne diseases, or plantlet production using vegetative propagation is limited. In contrast, plant tissue culture allows for large-scale propagation ...
Source: Applied Microbiology and Biotechnology - June 13, 2020 Category: Microbiology Authors: Kher MM, Shekhawat MS, Nataraj M, Teixeira da Silva JA Tags: Appl Microbiol Biotechnol Source Type: research

Could “Hood’s Sarsaparilla” Root Out Uncle Sam’s Rash of Pains?
Before the onetime sassafras-based “root beer” of today, sarsaparilla (pronounced “sass-puh-RILL-uh”;Smilax sp.) reigned as America ’s vine for flavoring beverages and remedies. Originally a Native American treatment for gastrointestinal and dermatologic complaints, sarsaparilla began to be used for “blood disorders,” scurvy, scrofula, syphilis, and even leprosy. Popularizing this panacea was Vermont native Charles Ira Hoo d (1845 to 1922), who had moved to Lowell, Massachusetts, to apprentice as a pharmacist. After compounding his namesake sarsaparilla in 1876, Hood marketed it nationally with color lithogra...
Source: Anesthesiology - March 10, 2020 Category: Anesthesiology Source Type: research

Indian Sarsaparilla (Hemidesmus indicus): Recent progress in research on ethnobotany, phytochemistry and pharmacology
ConclusionsThe study presents an exhaustive and updated review on the traditional, pharmacological and phytochemical aspects of H. indicus with notes on its quality control and toxicological information. Although the crude extracts of H. indicus exhibit an array of pharmacological activities, it is high time to identify more active phyto-constituents by bioactivity-guided isolation besides elucidating their structure-activity relationship. More designed investigations are needed to comprehend the multi-target network pharmacology, to clarify the molecular mode of action and to ascertain the efficacious doses of H. indicus....
Source: Journal of Ethnopharmacology - January 31, 2020 Category: Drugs & Pharmacology Source Type: research

Investigation of the preliminary mechanism of action for the acute anti-inflammatory activity of the methanol extract of Smilax ornata Lem.
ConclusionThe methanol extract of Smilax ornata Lem. produced significant anti-inflammatory activity in the bradykinin-induced and prostaglandin-induced oedema models. It is possible that the mechanism by which it acts is by reducing the concentration or blocking the action of these mediators.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - October 31, 2019 Category: Drugs & Pharmacology Source Type: research

Investigation of the anti-inflammatory and the analgesic effects of the extracts from Smilax ornata Lem. (Jamaican sarsaparilla) plant
ConclusionThe present study provided scientific justification that the extracts of Smilax ornata Lem. possess significant anti-inflammatory and analgesic activities.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - May 5, 2019 Category: Drugs & Pharmacology Source Type: research

[Mercury or sarsaparilla. On the pharmacotherapy of venereal diseases by Johannes Franc (1649-1725) and Friedrich Hoffmann (1660-1742)].
Abstract In the late 17th and early 18th centuries, ancient humoral pathology was gradually complemented by new concepts of medical theory. Two important theories that emerged in this context were iatrochemistry and iatrophysics. The physician Johannes Franc (1649-1725) from Ulm and Friedrich Hoffmann (1660-1742), the first professor of the medical faculty of the Fridericiana in Halle (Saale), are representatives of these concepts. In their writings, they conveyed specific instructions for broader therapeutic treatment including various forms of medication. The iatrochemist Franc recorded his therapies in...
Source: Der Urologe. Ausg. A - March 19, 2019 Category: Urology & Nephrology Authors: Schochow M, Winckelmann HJ, Steger F Tags: Urologe A Source Type: research

Sarsaparilla (Smilax Glabra Rhizome) Extract Activates Redox-Dependent ATM/ATR Pathway to Inhibit Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - November 7, 2017 Category: Cancer & Oncology Authors: Tiantian She Junnan Feng Shenyi Lian Ruobing Li Chuanke Zhao Guoliang Song Jie Luo Rouxianguli Dawuti Shaoqing Cai Like Qu Chengchao Shou Source Type: research

Sarsaparilla (Smilax Glabra Rhizome) Extract Activates Redox-Dependent ATM/ATR Pathway to Inhibit Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy.
Abstract Sarsaparilla (Smilax Glabra Rhizome) exerts growth inhibitory effect on multiple cancer cells in vitro and in vivo, and redox-dependent persistent activation of ERK1/2 has been reported to underlie this effect. Here, we report an activation of ATM/ATR-dependent signaling pathway also as a mechanism for the cancer cell growth inhibition induced by the supernatant fraction of the water-soluble extract from sarsaparilla (SW). SW treatment (3.5 μg/μL) promoted the phosphorylations of ATM, ATR, and CHK1 in AGS and HT-29 cells. The ATM kinase inhibitor, KU55933, could reverse SW-induced ERK phosphory...
Source: Nutrition and Cancer - November 7, 2017 Category: Cancer & Oncology Authors: She T, Feng J, Lian S, Li R, Zhao C, Song G, Luo J, Dawuti R, Cai S, Qu L, Shou C Tags: Nutr Cancer Source Type: research