Cancers, Vol. 14, Pages 2130: Prognostic Factors after Surgery for Salivary Gland Cancer; What Is New, and What Is Next?
lzano Salivary gland cancers account approximately for 7% of all head and neck tumors [...] (Source: Cancers)
Source: Cancers - April 24, 2022 Category: Cancer & Oncology Authors: Angelo Camaioni Pietro De Luca Francesco Antonio Salzano Tags: Editorial Source Type: research

Expression of Mucins in Different Entities of Salivary Gland Cancer: Highest Expression of Mucin-1 in Salivary Duct Carcinoma
AbstractTherapeutic options for advanced salivary gland cancer (SGC) are rare. Therefore, it was the aim of this study to investigate the extent and intensity of Mucin-1 (MUC1), Mucin-16 (MUC16), and Mucin-5AC (MUC5AC) as potential molecular targets using immunohistochemistry. The medical records of all patients who underwent primary surgery for salivary gland cancer with curative intent in a tertiary referral center between 1990 and 2018 were reviewed. Immunohistochemical staining for MUC1, MUC16, and MUC5AC was performed for all patients with sufficient formalin-fixed paraffin-embedded material, and a semi-quantitative c...
Source: Head and Neck Pathology - April 7, 2022 Category: Pathology Source Type: research

Radiographic-anatomy, natural history and extension pathways of parotid and submandibular gland cancers
Radiother Oncol. 2022 Mar 11:S0167-8140(22)00130-X. doi: 10.1016/j.radonc.2022.03.005. Online ahead of print.ABSTRACTIntensity-modulated radiotherapy has been widely used routinely in recent past years for post-operative radiotherapy of salivary gland cancers Because of the sharp dose fall off outside of target volumes with IMRT, each volume must be strictly and rigorously defined, as the areas not specifically included in the target volume will not be treated to a therapeutic dose. The selection and delineation of these volumes is complex and requires extensive knowledge of parotid and submandibular gland cancer radiograp...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 15, 2022 Category: Radiology Authors: J Biau C Nutting J A Langendijk T Fr édéric-Moreau J Thariat L Piram R Bellini N Saroul N Pham Dang B O'Sullivan J Giralt P Blanchard J Bourhis M Lapeyre Source Type: research

Radiographic-anatomy, natural history and extension pathways of parotid and submandibular gland cancers
Radiother Oncol. 2022 Mar 11:S0167-8140(22)00130-X. doi: 10.1016/j.radonc.2022.03.005. Online ahead of print.ABSTRACTIntensity-modulated radiotherapy has been widely used routinely in recent past years for post-operative radiotherapy of salivary gland cancers Because of the sharp dose fall off outside of target volumes with IMRT, each volume must be strictly and rigorously defined, as the areas not specifically included in the target volume will not be treated to a therapeutic dose. The selection and delineation of these volumes is complex and requires extensive knowledge of parotid and submandibular gland cancer radiograp...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 15, 2022 Category: Radiology Authors: J Biau C Nutting J A Langendijk T Fr édéric-Moreau J Thariat L Piram R Bellini N Saroul N Pham Dang B O'Sullivan J Giralt P Blanchard J Bourhis M Lapeyre Source Type: research

Radiographic-anatomy, natural history and extension pathways of parotid and submandibular gland cancers
Radiother Oncol. 2022 Mar 11:S0167-8140(22)00130-X. doi: 10.1016/j.radonc.2022.03.005. Online ahead of print.ABSTRACTIntensity-modulated radiotherapy has been widely used routinely in recent past years for post-operative radiotherapy of salivary gland cancers Because of the sharp dose fall off outside of target volumes with IMRT, each volume must be strictly and rigorously defined, as the areas not specifically included in the target volume will not be treated to a therapeutic dose. The selection and delineation of these volumes is complex and requires extensive knowledge of parotid and submandibular gland cancer radiograp...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 15, 2022 Category: Radiology Authors: J Biau C Nutting J A Langendijk T Fr édéric-Moreau J Thariat L Piram R Bellini N Saroul N Pham Dang B O'Sullivan J Giralt P Blanchard J Bourhis M Lapeyre Source Type: research

Radiographic-anatomy, natural history and extension pathways of parotid and submandibular gland cancers
Radiother Oncol. 2022 Mar 11:S0167-8140(22)00130-X. doi: 10.1016/j.radonc.2022.03.005. Online ahead of print.ABSTRACTIntensity-modulated radiotherapy has been widely used routinely in recent past years for post-operative radiotherapy of salivary gland cancers Because of the sharp dose fall off outside of target volumes with IMRT, each volume must be strictly and rigorously defined, as the areas not specifically included in the target volume will not be treated to a therapeutic dose. The selection and delineation of these volumes is complex and requires extensive knowledge of parotid and submandibular gland cancer radiograp...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 15, 2022 Category: Radiology Authors: J Biau C Nutting J A Langendijk T Fr édéric-Moreau J Thariat L Piram R Bellini N Saroul N Pham Dang B O'Sullivan J Giralt P Blanchard J Bourhis M Lapeyre Source Type: research

Elective Neck Treatment for Clinically Node-Negative Salivary Gland Cancer: Observation, Neck Dissection, or Neck Irradiation?
We present a single institution experience of cN0 salivary gland cancer cases with primary endpoints of local and regional recurrence. We compared four management approaches; observation (None), elective neck dissection (END), elective neck irradiation (ENI), and combined elective neck dissection and neck irradiation (END+ENI). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 11, 2022 Category: Radiology Authors: E. Ilori, B. Hair, L. Rybicki, B.B. Burkey, J.L. Geiger, E. Lamarre, B. Prendes, J. Ku, D. Chute, C. Griffith, N.M. Woody, S. Koyfman, S.R. Campbell Tags: 109 Source Type: research

Outcomes and Prognostic Factors in Acinic Cell Carcinoma of the Parotid Gland: Mature Results From a Single Institution
Acinic cell carcinoma is a rare subtype of salivary gland cancer, with little published data on management or survival outcomes. We aimed to describe a cohort of patients from a single institution, and to identify factors that impacted oncologic outcomes. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 11, 2022 Category: Radiology Authors: P.E. Romine, J. Voutsinas, Q. Wu, M. Tratt, J.J. Liao, U. Parvathaneni, B. Barber, J. Dillon, M.A. Timoshchuk, N. Futran, J. Houlton, G.E. Laramore, R.G. Martins, K.D. Eaton, C.P. Rodriguez Tags: 188 Source Type: research

NCCN Guidelines ® Insights: Head and Neck Cancers, Version 1.2022
J Natl Compr Canc Netw. 2022 Mar;20(3):224-234. doi: 10.6004/jnccn.2022.0016.ABSTRACTThe NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity (including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer, salivary gland cancer, and mucosal melanoma (MM) are also addressed. The specific site of disease, stage, and pathologic findings guide treatment (eg, the appropriate surgical procedure, radiation targets, dose and fractionation of radiation, indications for systemic therapy). The NCCN Head and Neck Cancers Panel meets at least annually to review comments from review...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 11, 2022 Category: Cancer & Oncology Authors: Jimmy J Caudell Maura L Gillison Ellie Maghami Sharon Spencer David G Pfister Douglas Adkins Andrew C Birkeland David M Brizel Paul M Busse Anthony J Cmelak A Dimitrios Colevas David W Eisele Thomas Galloway Jessica L Geiger Robert I Haddad Wesley L Hicks Source Type: research