Distribution of sentinel nodes from parotid tumors –A feasibility study
ConclusionsThe use of SN-technique in the planning of surgical treatment of parotid tumors seems feasible. It may be of clinical value for patients with parotid cancer to enable a more accurate staging and to detect occult metastasis in the SNs within the parotid as well as in the neck, enabaling the possibility to surgically remove all positive SNs at primary surgery and with reduced surgical morbidity. (Source: Cancer Medicine)
Source: Cancer Medicine - September 30, 2023 Category: Cancer & Oncology Authors: Lalle Hammarstedt ‐Nordenvall,
Rusana Bark,
Alexandra Elliot,
Mathias Von Beckerath,
Caroline Gahm Tags: RESEARCH ARTICLE Source Type: research
Current management and future challenges in salivary glands cancer
Salivary gland cancers (SGCs) are rare, accounting for less than 5% of all malignancies of the head and neck region, and are morphologically heterogeneous. The diagnosis is mainly based on histology, with the complementary aid of molecular profiling, which is helpful in recognizing some poorly differentiated, borderline, or atypical lesions. Instrumental imaging defines the diagnosis, representing a remarkable tool in the treatment plan. Ultrasound and magnetic resonance are the most common procedures used to describe the primary tumour. The treatment of SGCs is multimodal and consists of surgery, radiotherapy, and systemi...
Source: Frontiers in Oncology - September 19, 2023 Category: Cancer & Oncology Source Type: research
PSMA-targeted therapy for non-prostate cancers
Radioligand therapy (RLT) agents are demonstrating a crucial role in the clinical approach to aggressive malignancies such as metastatic castrate-resistant prostate cancer (m-CRPC). With the recent FDA approval of prostate-specific membrane antigen (PSMA)-targeted RLT for m-CRPC, the field has broadened its gaze to explore other cancers that express PSMA in the tumor parenchyma or tumor neovasculature. In this review article, we discuss current progress in the clinical use of PSMA RLTs in non-prostate cancers such salivary gland cancers, renal cell carcinoma, high grade glioma, and soft tissue sarcoma. We highlight early r...
Source: Frontiers in Oncology - August 14, 2023 Category: Cancer & Oncology Source Type: research
