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Vaccination: Measles Vaccine

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Total 1232 results found since Jan 2013.

Vaccines such as the MMR (Measles-Mumps-Rubella) against COVID-19 in Brazil: a missed chance?
An Acad Bras Cienc. 2023 Feb 17;95(suppl 1):e20220924. doi: 10.1590/0001-3765202320220924. eCollection 2023.NO ABSTRACTPMID:36820732 | DOI:10.1590/0001-3765202320220924
Source: An Acad Bras Cienc - February 23, 2023 Category: Science Authors: Antonio Ara újo Liliane Lins-Kusterer Eduardo Netto Source Type: research

Vaccinomics: A scoping review
CONCLUSION: This scoping review identified numerous genetic associations with vaccine immunogenicity and several genetic associations with vaccine safety. Most associations were only reported in one study. This illustrates both the potential of and need for investment in vaccinomics. Current research in this field is focused on systems and genetic-based studies designed to identify risk signatures for serious vaccine reactions or diminished vaccine immunogenicity. Such research could bolster our ability to develop safer and more effective vaccines.PMID:36803903 | DOI:10.1016/j.vaccine.2023.02.009
Source: Vaccine - February 21, 2023 Category: Allergy & Immunology Authors: Matthew Z Dudley Jennifer E Gerber Haley Budigan Ni Madeleine Blunt Taylor A Holroyd Bruce C Carleton Gregory A Poland Daniel A Salmon Source Type: research

Accounting for Adverse Events Following Immunization in Economic Evaluation: Systematic Review of Economic Evaluations of Pediatric Vaccines Against Pneumococcus, Rotavirus, Human Papillomavirus, Meningococcus and Measles-Mumps-Rubella-Varicella
DiscussionAlthough (mild) AEFI were demonstrated for all five studied vaccines, only a quarter of reviewed studies accounted for these, mostly in an incomplete and inaccurate manner. We provide guidance on which methods to use to better quantify the impact of AEFI on both costs and health outcomes. Policymakers should be aware that the impact of AEFI on cost-effectiveness is likely to be underestimated in the majority of economic evaluations.
Source: PharmacoEconomics - February 21, 2023 Category: Health Management Source Type: research

Recombinant measles virus encoding the spike protein of SARS-CoV-2 efficiently induces Th1 responses and neutralizing antibodies that block SARS-CoV-2 variants
In this study, we developed a recombinant MeV expressing the full-length SARS-CoV-2 spike protein (rMeV-S) and tested its efficacy using mouse and hamster models. In hCD46Tg mice, two-dose rMeV-S vaccination induced higher Th1 secretion and humoral responses than one-dose vaccination. Interestingly, neutralizing antibodies induced by one-dose and two-dose rMeV-S immunization effectively blocked the entry of the α, β, γ, and δ variants of SARS-CoV-2. Furthermore, two-dose rMeV-S immunization provided complete protection against SARS-CoV-2 in the hamster model. These results suggest the potential of rMeV-S as a vaccine c...
Source: Vaccine - February 15, 2023 Category: Allergy & Immunology Authors: Hye Won Kwak Hyo-Jung Park Seo-Yeon Jung Eun Young Oh Sang-In Park Yeonhwa Kim Hyeong-Jun Park Sohyun Park You-Jin Kim Hae Li Ko Jung-Ah Lee Hyeran Won Yun-Ho Hwang Seo Yeon Kim Se Eun Kim Seoung Eun Bae Minhyuk Yoon Jae-Ouk Kim Manki Song Su Jeen Lee Ki- Source Type: research

Cost-effectiveness of sub-national geographically targeted vaccination programs: A systematic review
Vaccine. 2023 Feb 11:S0264-410X(23)00132-9. doi: 10.1016/j.vaccine.2023.02.006. Online ahead of print.ABSTRACTImmunization is an essential component of national health plans. However, the growing number of new vaccine introductions, vaccination campaigns and increasing administrative costs create logistic and financial challenges, especially in resource-limited settings. Sub-national geographic targeting of vaccination programs is a potential strategy for governments to reduce the impact of infectious disease outbreaks while optimizing resource allocation and reducing costs, promoting sustainability of critically important...
Source: Vaccine - February 13, 2023 Category: Allergy & Immunology Authors: Marya Getchell Ericka Joinelle Mantaring Kaisin Yee Paul Pronyk Source Type: research

Systematic review and meta-analysis of epidemiologic data on vaccine response in relation to exposure to five principal perfluoroalkyl substances
CONCLUSIONS: Epidemiologic data on immunosuppression and five principal PFAS suggest an association, with support across antibodies against multiple types of antigens. Data on Diphtheria, Rubella, and Tetanus were more supportive of an association than for other antibodies, and support was greater for associations with PFOA, PFOS, and PFHxS, than for PFNA or PFDA. The data on any specific antibody were scarce. Confounding factors that might account for the relation were not identified. Nearly all studies evaluated were judged to have a low or moderate risk of bias.PMID:36764183 | DOI:10.1016/j.envint.2023.107734
Source: Environment International - February 10, 2023 Category: Environmental Health Authors: Lori Crawford Scott A Halperin Michael W Dzierlenga Becky Skidmore Matthew W Linakis Shinichi Nakagawa Matthew P Longnecker Source Type: research