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Procedure: Perfusion
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Total 15121 results found since Jan 2013.
DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis
Conclusions: Endothelial DNMT1 acts as one of the key epigenetic factors to mediate the hemodynamically regulated EndoMT at least through repressing the expression of ALDH2, ALDH3A1, and ALDH6A1. Supplementation with carnosine and acetate may have a great potential in the prevention and treatment of atherosclerosis.PMID:37649604 | PMC:PMC10465216 | DOI:10.7150/thno.84427
Source: Atherosclerosis - August 31, 2023 Category: Cardiology Authors: Jianan Zhao Chuanrong Zhao Fangfang Yang Zhitong Jiang Juanjuan Zhu Weijuan Yao Wei Pang Jing Zhou Source Type: research
Permissive hypercapnia and oxygenation impairment in premature ventilated infants
CONCLUSIONS: Increased carbon dioxide levels were significantly associated with impaired oxygenation in preterm infants with respiratory distress syndrome or bronchopulmonary dysplasia.PMID:37647975 | DOI:10.1016/j.resp.2023.104144
Source: Respiratory Care - August 30, 2023 Category: Respiratory Medicine Authors: Theodore Dassios Emma E Williams Ourania Kaltsogianni Anne Greenough Source Type: research
Lung ultrasound-guided best positive end-expiratory pressure in neonatal anesthesia: a proposed randomized, controlled study
CONCLUSIONS: We expect a significant reduction of FiO2 in LUS-guided ventilation.IMPACT: Lung atelectasis is extremely common in neonatal anesthesia, because of the physiology of the neonatal lung and chest wall and leads to hypoxemia, being a lung area with a perfusion/ventilation mismatch. Raising inspired fraction of oxygen can overcome temporarily hypoxemia but oxygen is a toxic compound for newborns. Lung ultrasound (LUS) can detect atelectasis at bedside and be used to optimize ventilator settings including choice of positive end-expiratory pressure (PEEP). This randomized controlled trial (RCT) aims at demonstrating...
Source: Pediatric Research - August 30, 2023 Category: Pediatrics Authors: Anna Camporesi Ugo Maria Pierucci Giuseppe Paladini Andrea Gentile Danilo Buonsenso Gloria Pelizzo Source Type: research
Permissive hypercapnia and oxygenation impairment in premature ventilated infants
CONCLUSIONS: Increased carbon dioxide levels were significantly associated with impaired oxygenation in preterm infants with respiratory distress syndrome or bronchopulmonary dysplasia.PMID:37647975 | DOI:10.1016/j.resp.2023.104144
Source: Respiratory Care - August 30, 2023 Category: Respiratory Medicine Authors: Theodore Dassios Emma E Williams Ourania Kaltsogianni Anne Greenough Source Type: research
Predicting glypican-3 expression in hepatocellular carcinoma: A comprehensive analysis using combined contrast-enhanced ultrasound and clinical factors
CONCLUSION: Preoperative integration of CEUS features and clinical factors can non-invasively and effectively identify GPC3-positive HCC patients, providing valuable assistance in making personalized treatment decisions.PMID:37638421 | DOI:10.3233/CH-231912
Source: Clinical Hemorheology and Microcirculation - August 28, 2023 Category: Hematology Authors: Nana Li Tiantian Dong Peihua Wang Qi Li Fang Nie Source Type: research
The jugular venous-to-arterial < mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" > < mml:semantics > < mml:msub > < mml:mi > P < /mml:mi > < mml:mrow > < mml:mi > C < /mml:mi > < mml:msub > < mml:mi > O < /mml:mi > < mml:mn > 2 < /mml:mn > < /mml:msub > < /mml:mrow > < /mml:msub > < mml:annotation > ${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$ < /mml:annotation > < /mml:semantics > < /mml:math > difference during rebreathing and end-tidal forcing: Relationship with cerebral perfusion
We examined two assumptions of the modified rebreathing technique for the assessment of the ventilatory central chemoreflex (CCR) and cerebrovascular CO2 reactivity (CVR), hypothesizing: (1) that rebreathing abolishes the gradient between the partial pressures of arterial and brain tissue CO2 [measured via the surrogate jugular venous P C O 2 ${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$ and arterial P C O 2 ${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$ difference (Pjv-a CO2 )] and (2) rebreathing eliminates the capacity of CVR to influence the Pjv-a CO2 difference, and thus affect CCR sensitivity. We also evaluated ...
Source: The Journal of Physiology - August 28, 2023 Category: Physiology Authors: Jay M J R Carr Trevor A Day Philip N Ainslie Ryan L Hoiland Source Type: research
Predicting glypican-3 expression in hepatocellular carcinoma: A comprehensive analysis using combined contrast-enhanced ultrasound and clinical factors
CONCLUSION: Preoperative integration of CEUS features and clinical factors can non-invasively and effectively identify GPC3-positive HCC patients, providing valuable assistance in making personalized treatment decisions.PMID:37638421 | DOI:10.3233/CH-231912
Source: Clinical Hemorheology and Microcirculation - August 28, 2023 Category: Hematology Authors: Nana Li Tiantian Dong Peihua Wang Qi Li Fang Nie Source Type: research
