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Infectious Disease: Hepatitis B

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Total 12613 results found since Jan 2013.

Evaluation of the Curative Effect of Treating HBV-related Liver Fibrosis/Cirrhosis Based on the Method of Removing Turbidity and Regulating the Liver
CONCLUSION: Treatment based on removing turbidity and regulating the liver can effectively relieve the clinical symptoms of patients with HBV-related liver fibrosis/cirrhosis, promote the liver function to return to normal, relieve the degree of liver fibrosis, and reduce the LSM value. The curative effect is significant and worthy of clinical application.PMID:37708539
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Chunzhi Su Zheng Zhi Jinli Zhang Xianxin Meng Fei Su Panpan Zhou Source Type: research

Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research

Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research

Serum vitamin D deficiency is associated with increased risk of γδ T cell exhaustion in HBV-infected patients
In this study, we found that the frequency of circulating Vδ2+ T cell and serum levels of vitamin 25(OH)D3 were significantly decreased in patients with HBV. And serum 25(OH)D3 levels in HBV-infected patients were negatively correlated with HBV DNA load and PD-1 expression on γδ T cells. Interestingly, 1α,25(OH)2 D3 alleviated the exhaustion phenotype of Vδ2 T cells in HBV-infected patients and promoted IFN-β expression in human cytotoxic Vδ2 T cells in vitro. Collectively, these findings demonstrate that vitamin D plays a pivotal role in reversing γδ T-cell exhaustion and is highly promising target for ameliorati...
Source: Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Ke Li Eying Lu Qian Wang Ruirong Xu Wenhui Yuan Ruan Wu Ligong Lu Peng Li Source Type: research

Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research