Filtered By:
Drug: Metformin
This page shows you your search results in order of date. This is page number 10.
Order by Relevance | Date
Total 6422 results found since Jan 2013.
Case Report: Late-Onset Metformin-Associated Diarrhea
Am Fam Physician. 2023 Aug;108(2):Online.NO ABSTRACTPMID:37590844
Source: American Family Physician - August 17, 2023 Category: Primary Care Authors: Robert J Flaherty Source Type: research
Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in < em > db/db < /em > mice
This study aimed to determine the effect of loss of endothelial GR on organ fibrosis in the db/db model. Db/Db mice lacking endothelial GR showed more severe fibrosis in multiple organs compared to endothelial GR-replete db/db mice. Organ fibrosis could be substantially improved either through administration of a Wnt inhibitor or metformin. IL-6 is a key cytokine driving the fibrosis phenotype and is mechanistically linked to Wnt signaling. The db/db model is an important tool to study mechanisms of fibrosis and its phenotype in the absence of endothelial GR highlights the synergistic effects of Wnt signaling and inflammat...
Source: Am J Physiol Renal P... - August 17, 2023 Category: Urology & Nephrology Authors: Swayam Prakash Srivastava Julie E Goodwin Source Type: research
Case Report: Late-Onset Metformin-Associated Diarrhea
Am Fam Physician. 2023 Aug;108(2):Online.NO ABSTRACTPMID:37590844
Source: American Family Physician - August 17, 2023 Category: Primary Care Authors: Robert J Flaherty Source Type: research
Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in < em > db/db < /em > mice
This study aimed to determine the effect of loss of endothelial GR on organ fibrosis in the db/db model. Db/Db mice lacking endothelial GR showed more severe fibrosis in multiple organs compared to endothelial GR-replete db/db mice. Organ fibrosis could be substantially improved either through administration of a Wnt inhibitor or metformin. IL-6 is a key cytokine driving the fibrosis phenotype and is mechanistically linked to Wnt signaling. The db/db model is an important tool to study mechanisms of fibrosis and its phenotype in the absence of endothelial GR highlights the synergistic effects of Wnt signaling and inflammat...
Source: American Journal of Physiology. Renal Physiology - August 17, 2023 Category: Physiology Authors: Swayam Prakash Srivastava Julie E Goodwin Source Type: research
Case Report: Late-Onset Metformin-Associated Diarrhea
Am Fam Physician. 2023 Aug;108(2):Online.NO ABSTRACTPMID:37590844
Source: American Family Physician - August 17, 2023 Category: Primary Care Authors: Robert J Flaherty Source Type: research
Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in < em > db/db < /em > mice
This study aimed to determine the effect of loss of endothelial GR on organ fibrosis in the db/db model. Db/Db mice lacking endothelial GR showed more severe fibrosis in multiple organs compared to endothelial GR-replete db/db mice. Organ fibrosis could be substantially improved either through administration of a Wnt inhibitor or metformin. IL-6 is a key cytokine driving the fibrosis phenotype and is mechanistically linked to Wnt signaling. The db/db model is an important tool to study mechanisms of fibrosis and its phenotype in the absence of endothelial GR highlights the synergistic effects of Wnt signaling and inflammat...
Source: Am J Physiol Renal P... - August 17, 2023 Category: Urology & Nephrology Authors: Swayam Prakash Srivastava Julie E Goodwin Source Type: research
Case Report: Late-Onset Metformin-Associated Diarrhea
Am Fam Physician. 2023 Aug;108(2):Online.NO ABSTRACTPMID:37590844
Source: American Family Physician - August 17, 2023 Category: Primary Care Authors: Robert J Flaherty Source Type: research
Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in < em > db/db < /em > mice
This study aimed to determine the effect of loss of endothelial GR on organ fibrosis in the db/db model. Db/Db mice lacking endothelial GR showed more severe fibrosis in multiple organs compared to endothelial GR-replete db/db mice. Organ fibrosis could be substantially improved either through administration of a Wnt inhibitor or metformin. IL-6 is a key cytokine driving the fibrosis phenotype and is mechanistically linked to Wnt signaling. The db/db model is an important tool to study mechanisms of fibrosis and its phenotype in the absence of endothelial GR highlights the synergistic effects of Wnt signaling and inflammat...
Source: American Journal of Physiology. Renal Physiology - August 17, 2023 Category: Physiology Authors: Swayam Prakash Srivastava Julie E Goodwin Source Type: research
Case Report: Late-Onset Metformin-Associated Diarrhea
Am Fam Physician. 2023 Aug;108(2):Online.NO ABSTRACTPMID:37590844
Source: American Family Physician - August 17, 2023 Category: Primary Care Authors: Robert J Flaherty Source Type: research
Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in < em > db/db < /em > mice
This study aimed to determine the effect of loss of endothelial GR on organ fibrosis in the db/db model. Db/Db mice lacking endothelial GR showed more severe fibrosis in multiple organs compared to endothelial GR-replete db/db mice. Organ fibrosis could be substantially improved either through administration of a Wnt inhibitor or metformin. IL-6 is a key cytokine driving the fibrosis phenotype and is mechanistically linked to Wnt signaling. The db/db model is an important tool to study mechanisms of fibrosis and its phenotype in the absence of endothelial GR highlights the synergistic effects of Wnt signaling and inflammat...
Source: American Journal of Physiology. Renal Physiology - August 17, 2023 Category: Physiology Authors: Swayam Prakash Srivastava Julie E Goodwin Source Type: research
