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Total 30263 results found since Jan 2013.
Glycan node profiling of soluble and membrane glycoproteins in whole cell lysates
Anal Biochem. 2023 Sep 10:115317. doi: 10.1016/j.ab.2023.115317. Online ahead of print.ABSTRACTGlycan node analysis (GNA) is a molecularly bottom-up glycomics technique based on the relative quantification of glycan linkage-specific monosaccharide units ("glycan nodes"). It was originally applied to blood plasma/serum, where it detected and predicted progression, reoccurrence, and survival in different types of cancer. Here, we have adapted this technology to previously inaccessible membrane glycoproteins from cultured cells. The approach is facilitated by methanol/chloroform precipitation of cell lysates and a "liquid pha...
Source: Analytical Biochemistry - September 12, 2023 Category: Biochemistry Authors: Jes ús S Aguilar Díaz de León Jorvani Cruz Villarreal Erandi P Kapuruge Chad R Borges Source Type: research
Comparative Analysis of Donor Liver Allograft Outcomes in Hepatocellular Carcinoma Patients Who Underwent Liver Transplant
CONCLUSIONS: Similar outcomes can be achieved for hepatocellular carcinoma patients who undergo liver transplant with donations after brain death, donations after cardiac death, or donations after brain and cardiac death allografts, especially when strict donor selection criteria are applied.PMID:37698401 | DOI:10.6002/ect.2023.0119
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Abdulahad Abdulrab Mohammed Al-Ameri Zhisheng Zhou Shusen Zheng Source Type: research
Phosphotriesterase-related protein as a novel prognostic predictor for hepatocellular carcinoma patients
CONCLUSIONS: PTER protein expression is raised in HCC tissues and may be a potential prognostic predictor for HCC patients.PMID:37699602 | DOI:10.21037/cco-23-42
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Xiaofan Feng Yanan Zhou Shujie Pang Chun Yang Siyuan Wang Source Type: research
Direct comparison and reproducibility of two segmentation methods for multicompartment dosimetry: round robin study on radioembolization treatment planning in hepatocellular carcinoma
CONCLUSION: Anatomic segmentation-based dosimetry, versus 99mTc-MAA segmentation, results in lower absorbed doses with superior reproducibility. Higher volume compartments, such as normal tissue versus tumour, exhibit improved reproducibility.TRIAL REGISTRATION: NCT03295006.PMID:37698645 | DOI:10.1007/s00259-023-06416-9
Source: Molecular Medicine - September 12, 2023 Category: Molecular Biology Authors: Marnix Lam Etienne Garin Xavier Palard-Novello Armeen Mahvash Cheenu Kappadath Paul Haste Mark Tann Ken Herrmann Francesco Barbato Brian Geller Niklaus Schaefer Alban Denys Matthew Dreher Kirk D Fowers Vanessa Gates Riad Salem Source Type: research
Glycan node profiling of soluble and membrane glycoproteins in whole cell lysates
Anal Biochem. 2023 Sep 10;680:115317. doi: 10.1016/j.ab.2023.115317. Online ahead of print.ABSTRACTGlycan node analysis (GNA) is a molecularly bottom-up glycomics technique based on the relative quantification of glycan linkage-specific monosaccharide units ("glycan nodes"). It was originally applied to blood plasma/serum, where it detected and predicted progression, reoccurrence, and survival in different types of cancer. Here, we have adapted this technology to previously inaccessible membrane glycoproteins from cultured cells. The approach is facilitated by methanol/chloroform precipitation of cell lysates and a "liquid...
Source: Analytical Biochemistry - September 12, 2023 Category: Biochemistry Authors: Jes ús S Aguilar Díaz de León Jorvani Cruz Villarreal Erandi P Kapuruge Chad R Borges Source Type: research
Comparative Analysis of Donor Liver Allograft Outcomes in Hepatocellular Carcinoma Patients Who Underwent Liver Transplant
CONCLUSIONS: Similar outcomes can be achieved for hepatocellular carcinoma patients who undergo liver transplant with donations after brain death, donations after cardiac death, or donations after brain and cardiac death allografts, especially when strict donor selection criteria are applied.PMID:37698401 | DOI:10.6002/ect.2023.0119
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Abdulahad Abdulrab Mohammed Al-Ameri Zhisheng Zhou Shusen Zheng Source Type: research
A novel immunogenic cell death-related genes signature for predicting prognosis, immune landscape and immunotherapy effect in hepatocellular carcinoma
CONCLUSION: The ICD score exhibits a high degree of reliability for predicting prognosis and may provide valuable guidance for the selection of immunotherapy for HCC patients. This novel scoring system enables the estimation of clinical immunotherapy response for HCC patients, offering new opportunities for personalized immunotherapy.PMID:37698679 | DOI:10.1007/s00432-023-05370-1
Source: Cell Research - September 12, 2023 Category: Cytology Authors: Guangming Xu Yifan Jiang Yu Li Jiangzhen Ge Xiaofeng Xu Diyu Chen Jian Wu Source Type: research
Glycan node profiling of soluble and membrane glycoproteins in whole cell lysates
Anal Biochem. 2023 Nov 1;680:115317. doi: 10.1016/j.ab.2023.115317. Epub 2023 Sep 10.ABSTRACTGlycan node analysis (GNA) is a molecularly bottom-up glycomics technique based on the relative quantification of glycan linkage-specific monosaccharide units ("glycan nodes"). It was originally applied to blood plasma/serum, where it detected and predicted progression, reoccurrence, and survival in different types of cancer. Here, we have adapted this technology to previously inaccessible membrane glycoproteins from cultured cells. The approach is facilitated by methanol/chloroform precipitation of cell lysates and a "liquid phase...
Source: Analytical Biochemistry - September 12, 2023 Category: Biochemistry Authors: Jes ús S Aguilar Díaz de León Jorvani Cruz Villarreal Erandi P Kapuruge Chad R Borges Source Type: research
Matrine improves the hepatic microenvironment and reverses epithelial-mesenchymal transition in hepatocellular carcinoma by inhibiting the Wnt-1/ β-catenin signaling pathway
CONCLUSIONS: Matrine can reverse EMT, alleviate intrahepatic inflammation, and counteract immune depletion by inhibiting the Wnt-1/β-catenin signaling pathway in HCC.PMID:37692966 | PMC:PMC10492086
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Jianfei Shi Hua Zhang Guangjie Han Jinfeng Wang Xin Han Man Zhao Xiaoling Duan Lili Mi Ning Li Xiaolei Yin Cuizhen Li Fei Yin Source Type: research
