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Usefulness of tumor perfusion on cone-beam CT after hepatic arterial infusion port implantation for evaluating tumor response to hepatic arterial infusion chemotherapy in hepatocellular carcinoma treatment
CONCLUSION: Hyperperfusion tumors on CBCT showed a better tumor response to HAIC, with a 65% ORR in patients with HCC. Tumor perfusion on CBCT after implantation of the hepatic arterial infusion port was associated with the tumor response to HAIC.PMID:37695260 | DOI:10.4274/dir.2023.232311
Source: Diagnostic and Interventional Radiology - September 11, 2023 Category: Radiology Authors: Phan Nhan Hien Ho Jong Chun Jung Suk Oh Su Ho Kim Byung Gil Choi Source Type: research

Clinical, Gender, Socioeconomic Characteristics and Outcomes of Individuals Receiving Hepatitis B Treatment in Ethiopia: 18-Month Follow-Up
Am J Trop Med Hyg. 2023 Sep 11:tpmd230236. doi: 10.4269/ajtmh.23-0236. Online ahead of print.ABSTRACTThere is a lack of real-world data on hepatitis B (HBV) treatment in Africa. We conducted a single-center 18-month prospective cohort study in Ethiopia to understand clinical, laboratory, and demographic variables associated with HBV treatment. One hundred fifty HBV-positive patients were included: 51 on treatment, 99 with no treatment. Median age was similar between groups. Those on treatment were more likely to be male (86%), report higher coffee intake (90% versus 70%, P < 0.05), lower khat intake (0% versus 9%, P = 0...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Manaswita Tappata Marina Farah Chimaobi Anugwom Eden Bisrat Amir S Seid Jose D Debes Source Type: research

Usefulness of tumor perfusion on cone-beam CT after hepatic arterial infusion port implantation for evaluating tumor response to hepatic arterial infusion chemotherapy in hepatocellular carcinoma treatment
CONCLUSION: Hyperperfusion tumors on CBCT showed a better tumor response to HAIC, with a 65% ORR in patients with HCC. Tumor perfusion on CBCT after implantation of the hepatic arterial infusion port was associated with the tumor response to HAIC.PMID:37695260 | DOI:10.4274/dir.2023.232311
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 11, 2023 Category: Radiology Authors: Phan Nhan Hien Ho Jong Chun Jung Suk Oh Su Ho Kim Byung Gil Choi Source Type: research

Clinical, Gender, Socioeconomic Characteristics and Outcomes of Individuals Receiving Hepatitis B Treatment in Ethiopia: 18-Month Follow-Up
Am J Trop Med Hyg. 2023 Sep 11:tpmd230236. doi: 10.4269/ajtmh.23-0236. Online ahead of print.ABSTRACTThere is a lack of real-world data on hepatitis B (HBV) treatment in Africa. We conducted a single-center 18-month prospective cohort study in Ethiopia to understand clinical, laboratory, and demographic variables associated with HBV treatment. One hundred fifty HBV-positive patients were included: 51 on treatment, 99 with no treatment. Median age was similar between groups. Those on treatment were more likely to be male (86%), report higher coffee intake (90% versus 70%, P < 0.05), lower khat intake (0% versus 9%, P = 0...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Manaswita Tappata Marina Farah Chimaobi Anugwom Eden Bisrat Amir S Seid Jose D Debes Source Type: research

Usefulness of tumor perfusion on cone-beam CT after hepatic arterial infusion port implantation for evaluating tumor response to hepatic arterial infusion chemotherapy in hepatocellular carcinoma treatment
CONCLUSION: Hyperperfusion tumors on CBCT showed a better tumor response to HAIC, with a 65% ORR in patients with HCC. Tumor perfusion on CBCT after implantation of the hepatic arterial infusion port was associated with the tumor response to HAIC.PMID:37695260 | DOI:10.4274/dir.2023.232311
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 11, 2023 Category: Radiology Authors: Phan Nhan Hien Ho Jong Chun Jung Suk Oh Su Ho Kim Byung Gil Choi Source Type: research

Clinical, Gender, Socioeconomic Characteristics and Outcomes of Individuals Receiving Hepatitis B Treatment in Ethiopia: 18-Month Follow-Up
Am J Trop Med Hyg. 2023 Sep 11:tpmd230236. doi: 10.4269/ajtmh.23-0236. Online ahead of print.ABSTRACTThere is a lack of real-world data on hepatitis B (HBV) treatment in Africa. We conducted a single-center 18-month prospective cohort study in Ethiopia to understand clinical, laboratory, and demographic variables associated with HBV treatment. One hundred fifty HBV-positive patients were included: 51 on treatment, 99 with no treatment. Median age was similar between groups. Those on treatment were more likely to be male (86%), report higher coffee intake (90% versus 70%, P < 0.05), lower khat intake (0% versus 9%, P = 0...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Manaswita Tappata Marina Farah Chimaobi Anugwom Eden Bisrat Amir S Seid Jose D Debes Source Type: research

Usefulness of tumor perfusion on cone-beam CT after hepatic arterial infusion port implantation for evaluating tumor response to hepatic arterial infusion chemotherapy in hepatocellular carcinoma treatment
CONCLUSION: Hyperperfusion tumors on CBCT showed a better tumor response to HAIC, with a 65% ORR in patients with HCC. Tumor perfusion on CBCT after implantation of the hepatic arterial infusion port was associated with the tumor response to HAIC.PMID:37695260 | DOI:10.4274/dir.2023.232311
Source: Diagnostic and Interventional Radiology - September 11, 2023 Category: Radiology Authors: Phan Nhan Hien Ho Jong Chun Jung Suk Oh Su Ho Kim Byung Gil Choi Source Type: research

Canagliflozin reduces chemoresistance in hepatocellular carcinoma through PKM2-c-Myc complex-mediated glutamine starvation
In conclusion, our study showed that CANA re-sensitized HCC to CPT by inducing ferroptosis through dual effects on glycolysis and glutamine metabolism. This is a novel mechanism to increase chemosensitivity, which may provide compatible chemotherapy drugs for HCC.PMID:37696420 | DOI:10.1016/j.freeradbiomed.2023.09.006
Source: Free Radical Biology and Medicine - September 11, 2023 Category: Biology Authors: Yuan Zeng Haoran Jiang Xiangting Zhang Jun Xu Xiao Wu Qian Xu Weimin Cai Huiya Ying Ruoru Zhou Yingrong Ding Kanglei Ying Xian Song Zhuoyan Chen Liuwei Zeng Luying Zhao Fujun Yu Source Type: research

Clinical, Gender, Socioeconomic Characteristics and Outcomes of Individuals Receiving Hepatitis B Treatment in Ethiopia: 18-Month Follow-Up
Am J Trop Med Hyg. 2023 Sep 11:tpmd230236. doi: 10.4269/ajtmh.23-0236. Online ahead of print.ABSTRACTThere is a lack of real-world data on hepatitis B (HBV) treatment in Africa. We conducted a single-center 18-month prospective cohort study in Ethiopia to understand clinical, laboratory, and demographic variables associated with HBV treatment. One hundred fifty HBV-positive patients were included: 51 on treatment, 99 with no treatment. Median age was similar between groups. Those on treatment were more likely to be male (86%), report higher coffee intake (90% versus 70%, P < 0.05), lower khat intake (0% versus 9%, P = 0...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Manaswita Tappata Marina Farah Chimaobi Anugwom Eden Bisrat Amir S Seid Jose D Debes Source Type: research