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Total 30263 results found since Jan 2013.
Dysregulated microRNAs as a biomarker for diagnosis and prognosis of hepatitis B virus-associated hepatocellular carcinoma
World J Gastroenterol. 2023 Aug 21;29(31):4706-4735. doi: 10.3748/wjg.v29.i31.4706.ABSTRACTHepatocellular carcinoma (HCC) is a malignancy with a high incidence and fatality rate worldwide. Hepatitis B virus (HBV) infection is one of the most important risk factors for its occurrence and development. Early detection of HBV-associated HCC (HBV-HCC) can improve clinical decision-making and patient outcomes. Biomarkers are extremely helpful, not only for early diagnosis, but also for the development of therapeutics. MicroRNAs (miRNAs), a subset of non-coding RNAs approximately 22 nucleotides in length, have increasingly attrac...
Source: World Journal of Gastroenterology : WJG - September 4, 2023 Category: Gastroenterology Authors: Ming-He Zhang Yu-Feng Yuan Li-Juan Liu Yu-Xin Wei Wan-Yue Yin Lan-Zhuo-Yin Zheng Ying-Ying Tang Zhao Lv Fan Zhu Source Type: research
A model incorporating clinicopathologic and liver imaging reporting and data system-based magnetic resonance imaging features to identify hepatocellular carcinoma in LR-M observations
CONCLUSION: The combined model incorporating clinicopathologic and MRI features demonstrated a satisfactory prediction result for LR-M HCC.PMID:37665140 | DOI:10.4274/dir.2023.232215
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 4, 2023 Category: Radiology Authors: Xin-Xing Hu Dong Bai Zhen-Lei Wang Yi Zhang Jue Zhao Mei-Ling Li Jia Yang Lei Zhang Source Type: research
Dysregulated microRNAs as a biomarker for diagnosis and prognosis of hepatitis B virus-associated hepatocellular carcinoma
World J Gastroenterol. 2023 Aug 21;29(31):4706-4735. doi: 10.3748/wjg.v29.i31.4706.ABSTRACTHepatocellular carcinoma (HCC) is a malignancy with a high incidence and fatality rate worldwide. Hepatitis B virus (HBV) infection is one of the most important risk factors for its occurrence and development. Early detection of HBV-associated HCC (HBV-HCC) can improve clinical decision-making and patient outcomes. Biomarkers are extremely helpful, not only for early diagnosis, but also for the development of therapeutics. MicroRNAs (miRNAs), a subset of non-coding RNAs approximately 22 nucleotides in length, have increasingly attrac...
Source: World Journal of Gastroenterology : WJG - September 4, 2023 Category: Gastroenterology Authors: Ming-He Zhang Yu-Feng Yuan Li-Juan Liu Yu-Xin Wei Wan-Yue Yin Lan-Zhuo-Yin Zheng Ying-Ying Tang Zhao Lv Fan Zhu Source Type: research
A model incorporating clinicopathologic and liver imaging reporting and data system-based magnetic resonance imaging features to identify hepatocellular carcinoma in LR-M observations
CONCLUSION: The combined model incorporating clinicopathologic and MRI features demonstrated a satisfactory prediction result for LR-M HCC.PMID:37665140 | DOI:10.4274/dir.2023.232215
Source: Diagnostic and Interventional Radiology - September 4, 2023 Category: Radiology Authors: Xin-Xing Hu Dong Bai Zhen-Lei Wang Yi Zhang Jue Zhao Mei-Ling Li Jia Yang Lei Zhang Source Type: research
Combination transarterial chemoembolization and microwave ablation vs. microwave ablation monotherapy for hepatocellular carcinomas greater than 3 cm: a comparative study
CONCLUSION: The combination therapy provided significantly longer upfront LTP-free survival in HCCs >3 cm when compared with the MWA treatment alone, albeit with similar local tumor control and overall survival rates when accounting for additional locoregional therapies.PMID:37665139 | DOI:10.4274/dir.2023.232159
Source: Diagnostic and Interventional Radiology - September 4, 2023 Category: Radiology Authors: Jason Chiang Pradeep S Rajendran Frank Hao James Sayre Steven S Raman David S K Lu Justin P McWilliams Source Type: research
Transcription Factor JunB Suppresses Hepatitis C Virus Replication
Kobe J Med Sci. 2023 Aug 31;69(3):E86-E95.ABSTRACTWe previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK is known to have numerous target genes, including JunB, a member of activator protein-1 transcription factor family. However, the roles of JunB in the HCV life cycle and HCV-associated pathogenesis remain unclear. To clarify a physiological role of JunB in HCV infe...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Adi Ariffianto Lin Deng Saki Harada Yujiao Liang Chieko Matsui Takayuki Abe Ikuo Shoji Source Type: research
A model incorporating clinicopathologic and liver imaging reporting and data system-based magnetic resonance imaging features to identify hepatocellular carcinoma in LR-M observations
CONCLUSION: The combined model incorporating clinicopathologic and MRI features demonstrated a satisfactory prediction result for LR-M HCC.PMID:37665140 | DOI:10.4274/dir.2023.232215
Source: Diagnostic and Interventional Radiology - September 4, 2023 Category: Radiology Authors: Xin-Xing Hu Dong Bai Zhen-Lei Wang Yi Zhang Jue Zhao Mei-Ling Li Jia Yang Lei Zhang Source Type: research
Combination transarterial chemoembolization and microwave ablation vs. microwave ablation monotherapy for hepatocellular carcinomas greater than 3 cm: a comparative study
CONCLUSION: The combination therapy provided significantly longer upfront LTP-free survival in HCCs >3 cm when compared with the MWA treatment alone, albeit with similar local tumor control and overall survival rates when accounting for additional locoregional therapies.PMID:37665139 | DOI:10.4274/dir.2023.232159
Source: Diagnostic and Interventional Radiology - September 4, 2023 Category: Radiology Authors: Jason Chiang Pradeep S Rajendran Frank Hao James Sayre Steven S Raman David S K Lu Justin P McWilliams Source Type: research
Transcription Factor JunB Suppresses Hepatitis C Virus Replication
Kobe J Med Sci. 2023 Aug 31;69(3):E86-E95.ABSTRACTWe previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK is known to have numerous target genes, including JunB, a member of activator protein-1 transcription factor family. However, the roles of JunB in the HCV life cycle and HCV-associated pathogenesis remain unclear. To clarify a physiological role of JunB in HCV infe...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Adi Ariffianto Lin Deng Saki Harada Yujiao Liang Chieko Matsui Takayuki Abe Ikuo Shoji Source Type: research
A model incorporating clinicopathologic and liver imaging reporting and data system-based magnetic resonance imaging features to identify hepatocellular carcinoma in LR-M observations
CONCLUSION: The combined model incorporating clinicopathologic and MRI features demonstrated a satisfactory prediction result for LR-M HCC.PMID:37665140 | DOI:10.4274/dir.2023.232215
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 4, 2023 Category: Radiology Authors: Xin-Xing Hu Dong Bai Zhen-Lei Wang Yi Zhang Jue Zhao Mei-Ling Li Jia Yang Lei Zhang Source Type: research
Combination transarterial chemoembolization and microwave ablation vs. microwave ablation monotherapy for hepatocellular carcinomas greater than 3 cm: a comparative study
CONCLUSION: The combination therapy provided significantly longer upfront LTP-free survival in HCCs >3 cm when compared with the MWA treatment alone, albeit with similar local tumor control and overall survival rates when accounting for additional locoregional therapies.PMID:37665139 | DOI:10.4274/dir.2023.232159
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 4, 2023 Category: Radiology Authors: Jason Chiang Pradeep S Rajendran Frank Hao James Sayre Steven S Raman David S K Lu Justin P McWilliams Source Type: research
A model incorporating clinicopathologic and liver imaging reporting and data system-based magnetic resonance imaging features to identify hepatocellular carcinoma in LR-M observations
CONCLUSION: The combined model incorporating clinicopathologic and MRI features demonstrated a satisfactory prediction result for LR-M HCC.PMID:37665140 | DOI:10.4274/dir.2023.232215
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 4, 2023 Category: Radiology Authors: Xin-Xing Hu Dong Bai Zhen-Lei Wang Yi Zhang Jue Zhao Mei-Ling Li Jia Yang Lei Zhang Source Type: research
Combination transarterial chemoembolization and microwave ablation vs. microwave ablation monotherapy for hepatocellular carcinomas greater than 3 cm: a comparative study
CONCLUSION: The combination therapy provided significantly longer upfront LTP-free survival in HCCs >3 cm when compared with the MWA treatment alone, albeit with similar local tumor control and overall survival rates when accounting for additional locoregional therapies.PMID:37665139 | DOI:10.4274/dir.2023.232159
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 4, 2023 Category: Radiology Authors: Jason Chiang Pradeep S Rajendran Frank Hao James Sayre Steven S Raman David S K Lu Justin P McWilliams Source Type: research
