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Acute ischemic stroke: The role of emergency carotid endarterectomy in isolated extracranial internal carotid artery occlusion
CONCLUSIONS: Emergency CEA in isolated eICA occlusion has proved to be a safe and effective treatment option in selected patients. CT perfusion, imaging the ischemic penumbra and quantifying the tissue suitable for reperfusion, offers a valid support in the diagnostic-therapeutic workup. Indeed, we can infer that the area of the ischemic penumbra is directly proportional to the margin of clinical improvement after revascularization, supposing that the appropriate intervention timing is respect.PMID:37594376 | DOI:10.1177/17085381231192712
Source: Vascular - August 18, 2023 Category: Surgery Authors: Pierfilippo Acciarri Alice Camagni Maddalena Bressan Gladiol Zenunaj Ilaria Casetta Andrea Bernardoni Vincenzo Gasbarro Luca Traina Source Type: research

Comparing adverse Events of tenecteplase and alteplase: A Real-World analysis of the FDA adverse Event Reporting System (FAERS)
CONCLUSION: This study identified and compared signals of ADRs associated with tenecteplase and alteplase, although tenecteplase is as effective as alteplase and has advantages such as ease of use and affordability, it cannot replace alteplase in the treatment of AIS until its safety profile is fully recognized. Additionally, previously unreported ocular ADRs and pneumonia were identified, providing valuable insights into the relationship between ADRs and the use of these thrombolytic drugs. These findings underscore the importance of continuous monitoring and effective detection of AEs to ultimately enhance the safety of ...
Source: Expert Opinion on Drug Safety - August 9, 2023 Category: Drugs & Pharmacology Authors: Fang-E Shi Zhe Yu Chengyue Sun Peiliang Gao Haiyan Zhang Jihong Zhu Source Type: research

E-108 Endovascular treatment of patients with acute ischemic stroke due to underlying arterial dissection: a nationwide analysis
ConclusionsDespite a similar prevalence among patients admitted for AIS, CA dissections are associated with a higher rate of endovascular intervention and poorer short-term outcomes compared to VA dissections. This study provides essential epidemiologic and outcome data for the cerebrovascular neurosurgeon.Abstract E-108 Table 1Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections Characteristic Vertebral Artery Dissection, N = 2,562 Carotid Artery Dissection, N = 2,789 p-value1 Age (years), Mean (SD) 53 (17) 57 (17) <0.00...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., McCann, C., Wali, A., Wu, V., Esmail, S., Steinberg, J., Olson, S., Pannell, J., Khalessi, A., Santiago-Dieppa, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-125 Clinical outcomes of mechanical thrombectomy in posterior circulation tandem occlusions: multicenter experience
ConclusionMechanical thrombectomy for posterior circulation tandem occlusions is feasible with reasonable clinical outcomes, despite a high rate of rescue stenting.Disclosures M. Salem: None. G. Sioutas: None. M. Mohammaden: None. A. Luisa Kuhn: None. A. Luisa Kuhn: None. A. Luisa Kuhn: None. C. Tschoe: None. M. Tarek: None. A. Dmytriw: None. R. Regenhardt: None. S. Marioni: None. M. AbdalKader: None. G. Cortez: None. V. Srinivasan: None. T. Nguyen: None. S. Tjoumakaris: None. A. Puri: None. V. Pereira: None. J. Rabinov: None. J. Seigler: None. R. Hanel: None. S. Sheth: None. A. Siddiqui: None. E. Levy: None. D. Haussen: N...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Salem, M., Sioutas, G., Mohammaden, M., Luisa Kuhn, A., Luisa Kuhn, A., Luisa Kuhn, A., Tschoe, C., Tarek, M., Dmytriw, A., Regenhardt, R., Marioni, S., AbdalKader, M., Cortez, G., Srinivasan, V., Nguyen, T., Tjoumakaris, S., Puri, A., Pereira, V., Rabino Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

China stroke surveillance report 2021
AbstractSince 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China Stroke High-risk Population Screening and Intervention Program, an estimated 17.8 million [95% confidence interval (CI) 17.6 –18.0 million] adults in China had experienced a stroke in 2020, with 3.4 million (95% CI 3.3–3.5 million) experiencing their first-ever stroke and another 2.3 million (95% CI 2.2–2.4 million) dying as a result. Additionally, approximately 12.5% (95% CI 12.4–12.5%) of stroke survi...
Source: Military Medical Research - July 19, 2023 Category: International Medicine & Public Health Source Type: research

Tirofiban in the treatment of cancer-associated ischemic stroke
CONCLUSIONS: Early administration of tirofiban in the treatment of mild to moderate ischemic stroke is safe, which can reduce 24-hour and 7-day NIHSS scores and has potential value.PMID:37140310 | DOI:10.26355/eurrev_202304_32142
Source: Pharmacological Reviews - May 4, 2023 Category: Drugs & Pharmacology Authors: Z-M Zhang Z-H Lin G-L Zhu Source Type: research

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