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Condition: Hypertension
Therapy: Statin Therapy
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Total 489 results found since Jan 2013.
The association between bullous pemphigoid and comorbidities: a case-control study in Moroccan patients
CONCLUSION: This study showed that BP is associated with stroke and the presence of malignancy compared to the age-matched general population. This study also calls for investigation into the specific role of some drugs as inducing factors for BP.PMID:35339128
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - March 27, 2022 Category: Dermatology Authors: Hicham Titou Hasna Kerrouch Rachid Frikh Naoufal Hjira Source Type: research
Myocardial Infarction, Stroke, and All-Cause Mortality According to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study
CONCLUSION: Among the elderly, lower LDL-C was associated with decreased risks of MI and stroke. Lower LDL-C achieved by statins in the elderly was associated with a decreased risk of all-cause death during follow-up, suggesting that LDL-C paradox for the premature death risk in the elderly should not be applied to statin users. Intensive statin therapy should not be hesitated for older adults with cardiovascular risk factors including diabetes.PMID:35255552 | DOI:10.4093/dmj.2021.0225
Source: Diabetes and Metabolism Journal - March 7, 2022 Category: Endocrinology Authors: You-Bin Lee Minji Koo Eunjin Noh Soon Young Hwang Jung A Kim Eun Roh So-Hyeon Hong Kyung Mook Choi Sei Hyun Baik Geum Joon Cho Hye Jin Yoo Source Type: research
Association between low-density lipoprotein cholesterol and cardiovascular mortality in statin non-users: a prospective cohort study in 14.9 million Korean adults
ConclusionLDL-C had U-curve associations for CVD mortality. The associations and optimal ranges differed across CVD subtypes. Women and older adults had weaker positive associations than men and younger adults. Positive associations with ischaemic heart disease and ischaemic stroke were maintained in adults aged 75 –84 years.
Source: International Journal of Epidemiology - February 26, 2022 Category: Epidemiology Source Type: research
Aortic Pulse Wave Velocity as Adjunct Risk Marker for Assessing Cardiovascular Disease Risk: Prospective Study
CONCLUSIONS: Our results show that aortic stiffness predicted major adverse cardiovascular events in a cohort of elderly individuals, improving the performance of a widely used cardiovascular disease risk estimator. Aortic pulse wave velocity measurement is scalable, radiation-free, and easy to perform. Further studies on its applicability in cardiovascular disease risk assessment in primary care settings are needed.PMID:35139665 | DOI:10.1161/HYPERTENSIONAHA.121.17589
Source: Atherosclerosis - February 10, 2022 Category: Cardiology Authors: Carlos A Valencia-Hern ández Joni V Lindbohm Martin J Shipley Ian B Wilkinson Carmel M McEniery Sara Ahmadi-Abhari Archana Singh-Manoux Mika Kivimaki Eric J Brunner Source Type: research
Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: A cohort study
ConclusionsNight-onset strokes, compared with day-onset strokes, are associated with higher presenting neurologic severity, more frequent END, and worse 3-month functional outcome. These findings suggest that circadian time of onset is an important additional variable for inclusion in epidemiologic natural history studies and in treatment trials of neuroprotective and reperfusion agents for acute ischemic stroke.
Source: PLoS Medicine - February 4, 2022 Category: Internal Medicine Authors: Wi-Sun Ryu Source Type: research
Atherosclerosis: Known and unknown
Pathol Int. 2022 Jan 25. doi: 10.1111/pin.13202. Online ahead of print.ABSTRACTAtherosclerotic disease, such as myocardial infarction and stroke, is the number one killer worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic and environmental factors. In humans, it takes several decades until the clinical complications develop. There are many known risk factors for atherosclerosis, including hypercholesterolemia, hypertension, diabetes and smoking, which are involved in the pathogenesis of atherosclerosis; however, it is generally believed that atherosclerosis is vascular chronic infl...
Source: Atherosclerosis - January 25, 2022 Category: Cardiology Authors: Jianglin Fan Teruo Watanabe Source Type: research
Circulating Metabolome and White Matter Hyperintensities in Females and Males
Conclusions: Circulating metabolomic measures, including multiple lipid measures (e.g., lysophosphatidylcholines, hydroxysphingomyelins, low-density lipoprotein size and composition) and non-lipid metabolites (e.g., hydroxyphenylpyruvate, glucuronate) associate with WMH in a general population of middle-aged and older adults. Some metabolomic measures show marked sex specificities and explain sizable proportion of WMH variance.PMID:35050683 | DOI:10.1161/CIRCULATIONAHA.121.056892
Source: Circulation - January 20, 2022 Category: Cardiology Authors: Eeva Sliz Jean Shin Shahzad Ahmad Dylan M Williams Stefan Frenzel Friederike Gau ß Sarah E Harris Ann-Kristin Henning Maria Del C Valdes Hernandez Yi-Han Hu Beatriz Jim énez Muralidharan Sargurupremraj Carole Sudre Ruiqi Wang Katharina Wittfeld Qiong Ya Source Type: research
Arterial Atherosclerosis: Vascular Surgery Interventions
Am Fam Physician. 2022 Jan 1;105(1):65-72.ABSTRACTAtherosclerotic vascular disease is a leading cause of death worldwide. Atherosclerotic stenosis of the internal carotid or intracranial arteries causes up to 15% of strokes. Peripheral artery disease affects up to one in five people in the United States who are 60 years and older and nearly one-half of those who are 85 years and older. Renal artery stenosis may affect up to 5% of people with isolated hypertension and up to 40% of people with other atherosclerotic diseases. All patients with atherosclerotic vascular disease should receive a comprehensive program of guidelin...
Source: American Family Physician - January 14, 2022 Category: Primary Care Authors: Jonathon M Firnhaber C S Powell Source Type: research
