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Condition: Ischemic Stroke
Therapy: Statin Therapy
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Total 1639 results found since Jan 2013.
Polymorphism of IL-1B rs16944 (T/C) associated with serum levels of IL-1 β affects seizure susceptibility in ischemic stroke patients
CONCLUSIONS: The IL-1B rs16944 polymorphism had an independent association with seizure susceptibility after ischemic stroke. The mechanism might be associated with the regulation of IL-1β levels.PMID:36089763 | DOI:10.17219/acem/152738
Source: Adv Data - September 12, 2022 Category: Epidemiology Authors: Xiaojun Ma Liangwei Sun Xiaoli Li Yanlu Xu Qingyan Zhang Source Type: research
Risk of stroke in genetically verified familial hypercholesterolemia: A prospective matched cohort study
CONCLUSIONS: No significant excess risk of incident total and ischemic stroke in FH, and no difference in total stroke risk among the FH population with low, intermediate, and high statin exposure were observed. The observed relationship between FH and hemorrhagic stroke was no longer significant after adjusting for use of anti-thrombotic medication.PMID:36084445 | DOI:10.1016/j.atherosclerosis.2022.08.015
Source: Atherosclerosis - September 9, 2022 Category: Cardiology Authors: Karianne Svendsen Thomas Olsen Kathrine J Vinknes Liv J Mundal Kirsten B Holven Martin P Bogsrud Trond P Leren Jannicke Igland Kjetil Retterst øl Source Type: research
Perioperative Medical Management for Symptomatic Carotid Artery Interventions
AbstractPurpose of ReviewThe goal of this review is to provide the reader with an overview of symptomatic carotid stenosis and the approach to medical management of patients undergoing surgical intervention with both carotid endarterectomy (CEA) and carotid artery stenting (CAS).Recent FindingsCEA is recommended for patients with moderate to severe symptomatic carotid stenosis and transient ischemic attack (TIA) or non-disabling stroke. More recently CAS has also been shown to be a beneficial, less invasive option for patients with symptomatic carotid stenosis. All patients need urgent medical therapy to reduce the risk of...
Source: Current Treatment Options in Cardiovascular Medicine - September 9, 2022 Category: Cardiology Source Type: research
Does a History of Cancer Influence the Effectiveness of Statins on Outcomes After Stroke?
CONCLUSIONS: Treatment with statins after ischemic stroke may confer additional survival benefits for people who also have had cancer.PMID:36065808 | DOI:10.1161/STROKEAHA.122.038829
Source: Atherosclerosis - September 6, 2022 Category: Cardiology Authors: Muideen T Olaiya Nadine E Andrew Lachlan L Dalli David Ung Joosup Kim Vijaya Sundararajan Dominique A Cadilhac Amanda G Thrift Mark R Nelson Leonid Churilov Monique F Kilkenny PRECISE Investigators Source Type: research
Risk of stroke in genetically verified familial hypercholesterolemia: A prospective matched cohort study
Individuals with familial hypercholesterolemia (FH), causing severely elevated LDL-C, are expected to have a higher risk of ischemic stroke. The risk of hemorrhagic stroke and impact of statin use is however not known. We aimed to investigate the risk of incident total, ischemic and hemorrhagic stroke in individuals with FH compared to controls and to explore the association between cumulative statin use and risk of total stroke in FH.
Source: Atherosclerosis - August 27, 2022 Category: Cardiology Authors: Karianne Svendsen, Thomas Olsen, Kathrine J. Vinknes, Liv J. Mundal, Kirsten B. Holven, Martin P. Bogsrud, Trond P. Leren, Jannicke Igland, Kjetil Retterst øl Source Type: research
Dynamic changes of carotid atherosclerosis and their relations with stroke recurrence in patients with stroke or transient ischemic attack
CONCLUSION: Plaque progression occurred in 46% of stroke or TIA patients. Plaque progression was significantly associated with clinical stroke recurrence. Plaque regressed in 6.5% of patients. Patients with regression were younger than those without.PMID:35996235 | DOI:10.2174/1567202619666220822141804
Source: Current Neurovascular Research - August 23, 2022 Category: Neurology Authors: Eun-Ye Lim A-Hyun Cho Source Type: research
Statins for Primary Cardiovascular Disease Prevention
In the US, more than 126 million adults have been diagnosed with cardiovascular disease (CVD). Reducing the morbidity and mortality associated with CVD is a public health imperative. Accordingly, considerable resources and effort have been invested in determining not only how to effectively treat symptomatic coronary artery disease or ischemic stroke, but also on prevention of clinical CVD. Although elevated low-density lipoprotein (LDL) is associated with higher rates of CVD, there is uncertainty regarding the net benefit to risk ratio of using statins to reduce LDL among persons without CVD (primary prevention). This con...
Source: JAMA Internal Medicine - August 23, 2022 Category: Internal Medicine Source Type: research
