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Procedure: Hemodialysis
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Total 299 results found since Jan 2013.

Screening for transient ischemic attacks in hemodialysis patients.
Conclusions: Based on the first study of its kind to date, systematic screening for TIA has a low yield and cannot be relied on alone to identify patients at higher risk of cerebrovascular events. The confounding presence of symptoms attributable to uremia, neuropathy, hypotension and dysglycemia could reduce the sensitivity of established tests, with significant implications for the detection and treatment of TIA in dialysis. PMID: 23807647 [PubMed - as supplied by publisher]
Source: Journal of Nephrology - May 23, 2013 Category: Urology & Nephrology Authors: Power A, Edwards C, Sawyer J, Tandaric D, Dahdaleh D, Taube D, Duncan N Tags: J Nephrol Source Type: research

Hypertension in CKD
Conclusions: Compared to pre-HD blood pressure, home blood pressure seemed to be better in predicting mortality and cardiovascular outcomes.
Source: Nephrology Dialysis Transplantation - May 10, 2013 Category: Urology & Nephrology Authors: Iseki, K., Arima, H., Poulikakos, D., Banerjee, D., Malik, M. Tags: Abstracts Source Type: research

Hypertension - human studies
Conclusions:Higher predialysis SBP variability is associated with stroke on HD populations suggesting a potential role for cerebral perfusion instability. We confirm known associations between age, diabetes, pre-existent cerebrovascular disease and hypertension. In contrast to studies in non-dialysis patients we do not find an association between EPO dose and stroke. Interventional trials of blood pressure management on stroke are recommended.
Source: Nephrology Dialysis Transplantation - May 10, 2013 Category: Urology & Nephrology Authors: Power, A., Duncan, N., Pusey, C., Usvyat, L., Marcelli, D., Marelli, C., Kotanko, P., MONDO Consortium, Li, Z., Wang, J., Yuan, X., Wang, J., Wang, L., Ozkayar, N., Altun, B., Yildirim, T., Yilmaz, R., Dede, F., Hayran, M., Arici, M., Aki, T., Erdem, Y., Tags: Abstracts Source Type: research

Case report: hemodialysis for dabigatran overdose
3 out of 5 stars Hemodialysis for the Treatment of Pulmonary Hemorrhage from Dabigatran Overdose. Chen BC et al. Am J Kidney Dis 2013 Apr 15 [Epub ahead of print] Abstract Dabigatran (Pradaxa) is a competitive direct thrombin inhibitor approved in the United States for stroke prophylaxis in patients with nonvalvular atrial fibrillation. Although dabigatran has certain advantages over coumadin related to issues of dosing and testing, there is no readily available test to measure its anticoagulation effect, and there is no antidote to reverse bleeding. Recommendations for treating a patient with dabigatran-associated hemorr...
Source: The Poison Review - April 24, 2013 Category: Toxicology Authors: Leon Tags: Medical dabigatran hemodialysis hemorrhage overdose Source Type: news

Serum n-3 and n-6 Polyunsaturated Fatty Acid Profile as an Independent Predictor of Cardiovascular Events in Hemodialysis Patients
Conclusions: In hemodialysis patients, serum PUFA profile is unfavorably altered, and the low n-3-PUFA:AA ratios are independent predictors of CVD.
Source: American Journal of Kidney Diseases - April 19, 2013 Category: Urology & Nephrology Authors: Tetsuo Shoji, Ryusuke Kakiya, Tomoshige Hayashi, Yoshihiro Tsujimoto, Mika Sonoda, Hideaki Shima, Katsuhito Mori, Shinya Fukumoto, Hideki Tahara, Atushi Shioi, Tsutomu Tabata, Masanori Emoto, Yoshiki Nishizawa, Masaaki Inaba Tags: Dialysis Source Type: research

Blood Pressure Recordings During Hemodialysis Access Interventions: Implications for Acute Management
Abstract A retrospective study evaluating the pattern of blood pressure and its related complications before, during, and after percutaneous hemodialysis interventions was performed in patients presenting with asymptomatic hypertension. Hemodialysis patients undergoing percutaneous interventions including tunneled hemodialysis catheter insertion, percutaneous balloon angioplasty and thrombectomy procedure, and stage II hypertension (systolic blood pressure ≥160 mmHg) were included in this analysis. Blood pressure medications were not used while midazolam and fentanyl were routinely administered. Patients were followed f...
Source: Seminars In Dialysis - March 28, 2013 Category: Hematology Authors: Arif Asif, Hector Castro, Ahmed Ameen Waheed, Vishesh Kumar, Syed S Haqqie, Gary Siskin, Roy O Mathew, Darius Mason, Tushar Vachharajani, Ali Nayer, Donna Merrill, Muhammad UT Akmal, Loay Salman Tags: Investigation Source Type: research

Blood Pressure Recordings During Hemodialysis Access Interventions: Implications for Acute Management.
Abstract A retrospective study evaluating the pattern of blood pressure and its related complications before, during, and after percutaneous hemodialysis interventions was performed in patients presenting with asymptomatic hypertension. Hemodialysis patients undergoing percutaneous interventions including tunneled hemodialysis catheter insertion, percutaneous balloon angioplasty and thrombectomy procedure, and stage II hypertension (systolic blood pressure ≥160 mmHg) were included in this analysis. Blood pressure medications were not used while midazolam and fentanyl were routinely administered. Patients were f...
Source: Seminars in Dialysis - March 28, 2013 Category: Urology & Nephrology Authors: Asif A, Castro H, Waheed AA, Kumar V, Haqqie SS, Siskin G, Mathew RO, Mason D, Vachharajani T, Nayer A, Merrill D, Akmal MU, Salman L Tags: Semin Dial Source Type: research

Spinal ischemic stroke following dialysis: clinical and radiologic findings
Spinal cord ischemia (SCI) is a relatively common cause of noncompressive myelopathy.1 SCI frequently involves the thoracic or lumbar cord manifesting as acute painful paraparesis but may also involve the posterior columns and autonomic fibers.2 Most infarcts affect the central parts of the anterior spinal artery supply.2–4 Outcome depends on the initial severity of the neurologic deficits and may be surprisingly benign especially if proprioception remains intact.1,2 Because hypoperfusion may cause SCI,5,6 our goal was to describe SCI as a potential complication of hemodialysis-associated hypoperfusion.
Source: Neurology - February 25, 2013 Category: Neurology Authors: Honig, A., Gomori, J. M., Schneider, R., Makranz, C., Leker, R. R. Tags: All Medical/Systemic disease, All Cerebrovascular disease/Stroke, All Spinal Cord, Spinal cord infarction, Infarction CLINICAL/SCIENTIFIC NOTES Source Type: research

Low serum fetuin A levels and incident stroke in patients with maintenance haemodialysis
ConclusionsFetuin A deficiency is associated with a higher risk of incident stroke among prevalent HD patients.
Source: European Journal of Clinical Investigation - February 19, 2013 Category: Journals (General) Authors: Hung‐Yuan Chen, Yen‐Ling Chiu, Shih‐Ping Hsu, Mei‐Fen Pai, Ju‐Yeh Yang, Yu‐Sen Peng Tags: Original Article Source Type: research

Frequency of and risk factors for poor cognitive performance in hemodialysis patients
Conclusions: There is a high frequency of poor cognitive performance in hemodialysis patients, primarily affecting executive function. Risk factors for worse executive function include vascular risk factors as well as vascular disease. Normal performance on the MMSE does not preclude impaired cognitive function, because individuals with MMSE score ≥24 also have a high frequency of poor cognitive performance.
Source: Neurology - January 28, 2013 Category: Neurology Authors: Sarnak, M. J., Tighiouart, H., Scott, T. M., Lou, K. V., Sorensen, E. P., Giang, L. M., Drew, D. A., Shaffi, K., Strom, J. A., Singh, A. K., Weiner, D. E. Tags: All Cerebrovascular disease/Stroke, Memory, Neuropsychological assessment, Executive function ARTICLE Source Type: research

RCTs: Peginesatide in patients with anaemia and chronic kidney disease
Source: N Engl J Med Area: News In the New England Journal of Medicine, researchers report the results of four event-driven, randomised, controlled, open-label trials that compared the efficacy and safety of standard erythropoiesis-stimulating agent (ESA) therapy with peginesatide (Omontys), a peptide based ESA approved in the US in March 2012 for the treatment of anaemia caused by chronic kidney disease in adults who are undergoing dialysis.   The EMERALD 1 and EMERALD 2 studies involved patients undergoing haemodialysis. Cardiovascular safety was evaluated by analysis of an adjudicated composite safety end poin...
Source: NeLM - News - January 24, 2013 Category: Drugs & Pharmacology Source Type: news

Low Plasma α-Tocopherol Concentrations and Adverse Clinical Outcomes in Diabetic Hemodialysis Patients.
CONCLUSIONS: Plasma α-tocopherol concentrations were not independently associated with cardiovascular outcomes, infectious deaths, or all-cause mortality in diabetic hemodialysis patients. The lack of association can partly be explained by a confounding influence of malnutrition, which should be considered in the planning of trials to reduce cardiovascular risk in dialysis patients. PMID: 23335039 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - January 18, 2013 Category: Urology & Nephrology Authors: Espe KM, Raila J, Henze A, Blouin K, Schneider A, Schmiedeke D, Krane V, Pilz S, Schweigert FJ, Hocher B, Wanner C, Drechsler C, for the German Diabetes and Dialysis Study Investigators Tags: Clin J Am Soc Nephrol Source Type: research

Anatomic Brain Disease in Hemodialysis Patients: A Cross-sectional Study
Background: Although dialysis patients are at high risk of stroke and have a high burden of cognitive impairment, there are few reports of anatomic brain findings in the hemodialysis population. Using magnetic resonance imaging of the brain, we compared the prevalence of brain abnormalities in hemodialysis patients with that in a control population without known kidney disease. Study Design: Cross-sectional cohort. Setting & Participants: 45 maintenance hemodialysis patients and 67 controls without reported kidney disease, both without history of known stroke. Predictor: The primary predictor was dialysis status. Co...
Source: American Journal of Kidney Diseases - October 5, 2012 Category: Urology & Nephrology Authors: David A. Drew, Rafeeque Bhadelia, Hocine Tighiouart, Vera Novak, Tammy M. Scott, Kristina V. Lou, Kamran Shaffi, Daniel E. Weiner, Mark J. Sarnak Tags: Dialysis Source Type: research