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Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Use of EuroSCORE as a predictor of morbidity after cardiac surgery
Conclusion: EuroSCORE proved to be a good predictor of major postoperative morbidity in cardiac surgery: respiratory and dialysis-dependent renal failure.
Source: Revista Brasileira de Cirurgia Cardiovascular - June 3, 2014 Category: Cardiovascular & Thoracic Surgery Source Type: research

Extending the role of peritoneal dialysis: can we win hearts and minds?
Conclusion Both these applications require substantial further clinical evaluation before they can justify wider adoption but their potential to alleviate morbidity on a large and potentially highly cost-effective scale demands further study.
Source: Nephrology Dialysis Transplantation - August 27, 2014 Category: Urology & Nephrology Authors: Davies, S., Lally, F., Satchithananda, D., Kadam, U., Roffe, C. Tags: REVIEWS - BASIC SCIENCE AND TRANSLATIONAL NEPHROLOGY Source Type: research

Fabry nephropathy: indications for screening and guidance for diagnosis and treatment by the European Renal Best Practice
Fabry disease (FD) is an X-linked disorder of glycosphingolipid catabolism resulting in the accumulation of glycolipids including globotriaosylceramide in cells of various tissues resulting in end-organ manifestations. Initially, FD is typically characterized by angiokeratoma and recurrent episodes of neuropathic pain in the extremities occurring during childhood or adolescence. Most affected patients also exhibit a decreased ability to sweat. Later in life, FD results in left ventricular hypertrophy, proteinuria, renal failure and stroke. These later disease manifestations are non-specific and also common in diabetes, hyp...
Source: Nephrology Dialysis Transplantation - March 5, 2013 Category: Urology & Nephrology Authors: Terryn, W., Cochat, P., Froissart, R., Ortiz, A., Pirson, Y., Poppe, B., Serra, A., Van Biesen, W., Vanholder, R., Wanner, C. Tags: NDT PERSPECTIVES Source Type: research

Pulsatile-flow mechanical circulatory support (MCS) as a bridge to transplantation or recovery. Single-centre experience with the POLCAS system in 2014.
CONCLUSIONS: The POLCAS heart assist system is an effective method of treatment as a bridge to transplantation or recovery in patients with end-stage heart failure. Early survival after the treatment remains at a satisfactory level. The main problem is the large number of complications related to the therapy. PMID: 26702278 [PubMed]
Source: Polish Journal of Cardio-Thoracic Surgery - January 20, 2016 Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research

Mp284 * chronic renal failure worsens ischemic stroke severity and neurological consequences in mice
Source: Nephrology Dialysis Transplantation - May 13, 2016 Category: Urology & Nephrology Authors: Brazier, F., Assem, M., Henaut, L., Kamel, S., Massy, Z. A., Chillon, J.-M. Tags: CHRONIC KIDNEY DISEASE. PATHOPHYSIOLOGY, PROGRESSION & amp; RISK FACTORS - 2 Source Type: research

Experience with the SynCardia total artificial heart in a Canadian centre.
CONCLUSION: The TAH provides an alternative with low incidence of neurologic events in extremely fragile and complex patients waiting for heart transplantation. Complex and unusual anatomic conditions explained the current use of TAH. PMID: 28930049 [PubMed - as supplied by publisher]
Source: Canadian Journal of Surgery - September 22, 2017 Category: Surgery Authors: Nguyen A, Pellerin M, Perrault LP, White M, Ducharme A, Racine N, Carrier M Tags: Can J Surg Source Type: research

Intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation: A meta-analysis
Conclusion: ECMO support for LuTx showed better clinical outcomes compared to CPB.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Magouliotis, D., Svokos, A., Svokos, K., Olland, A., Massard, G., Tasiopoulou, V., Zacharoulis, D. Tags: Transplantation Source Type: research

Chronic organ failure in adult sickle cell disease.
Authors: Vichinsky E Abstract Sickle cell disease is now a chronic adult illness characterized by progressive multiorgan failure, particularly involving the brain and kidney. The etiology is multifactorial; it includes hemolysis and nitric oxide deficiency. As patients age, most experience neurologic insult. Twenty-five percent of older adults have had a clinical stroke and at least half of the population have had a silent infarct, cortical atrophy, and neurocognitive impairment. Periodic screening with neuroimaging and neurocognitive testing is recommended. Identification and correction of modifiable risk factors ...
Source: Hematology ASH Education Program - December 10, 2017 Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research

Sternal wound complications in patients undergoing orthotopic heart transplantation
ConclusionSternal wound infections impart a significant burden on patients with OHT. Causative organisms are predominantly virulent gram ‐negative bacteria. Therefore, a high index of suspicion must be maintained for early detection and treatment.
Source: Journal of Cardiac Surgery - February 25, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Tyler J. Wallen, Andreas Habertheuer, Jean P. Gottret, Matthew Kramer, Zara Abbas, Mary Siki, Reilly Hobbs, Charlie Vasquez, Maria Molina, Suhail Kanchwala, David Low, Michael Acker, Prashanth Vallabhajosyula Tags: ORIGINAL ARTICLE Source Type: research

Long-Term Single Centre Outcomes of Patients with Chronic Renal Dialysis Undergoing Cardiac Surgery
CONCLUSIONSCardiac surgery in DD-CRF patients is associated with high morbidity and mortality. Interestingly, overall mortality was mainly none cardiac-related, where elderly patients or those presented with CHF had the worst life expectancy. However, subsequent kidney transplantation positively impact long-term survival in such patients.
Source: The Annals of Thoracic Surgery - September 27, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

Long-Term Single Centre Outcomes of Patients with Chronic Renal Dialysis Undergoing Cardiac Surgery.
CONCLUSIONS: Cardiac surgery in DD-CRF patients is associated with high morbidity and mortality. Interestingly, overall mortality was mainly none cardiac-related, where elderly patients or those presented with CHF had the worst life expectancy. However, subsequent kidney transplantation positively impact long-term survival in such patients. PMID: 31563486 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 25, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Mourad F, Cleve N, Nowak J, Wendt D, Sander A, Demircioglu E, El Gabry M, Jakob H, Shehada SE Tags: Ann Thorac Surg Source Type: research

Outcome of CentriMag ™ extracorporeal mechanical circulatory support use in critical cardiogenic shock (INTERMACS 1) patients
ConclusionOur results demonstrate an excellent outcome with the use of the CentriMag ™ device in this seriously ill population. Despite requiring multiple procedures, over 58% of patients were discharged from hospital with 5-year survival of 46%.
Source: Indian Journal of Thoracic and Cardiovascular Surgery - September 29, 2020 Category: Cardiovascular & Thoracic Surgery Source Type: research

The long-term impact of perioperative red blood transfusion on patients undergoing cardiac surgery.
CONCLUSIONS: Patients with perioperative PRBC transfusions have increased operative and long-term mortality and hospital readmissions. Total units of PRBC transfused was directly associated with mortality and readmissions. PMID: 33171175 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 7, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Sultan I, Bianco V, Brown JA, Kilic A, Harbertheuer A, Aranda-Michel E, Navid F, Humar R, Wang Y, Gleason TG Tags: Ann Thorac Surg Source Type: research

A mortality risk score for heart transplants after contemporary ventricular assist device bridging
ConclusionsAmong patients bridged to OHT with newer generation centrifugal LVADs, older age, increasing bilirubin, longer ischemic time, and pre ‐OHT dialysis independently predicted post‐transplant mortality. The composite risk score based on these factors may assist in patient selection and prognostication in those supported with contemporary LVADs.
Source: Journal of Cardiac Surgery - December 7, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Lauren V. Huckaby, Laura M. Seese, Gavin Hickey, Ibrahim Sultan, Arman Kilic Tags: ORIGINAL ARTICLE Source Type: research