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Specialty: Cardiology
Condition: Trimethylamine
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Total 106 results found since Jan 2013.
Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke
CONCLUSIONS AND RELEVANCE: In this observational study, TMAO was associated with cerebral small vessel disease determined by WMHV and acute lacunar infarction. The association was independent of traditional vascular risk factors.PMID:37610752 | PMC:PMC10448304 | DOI:10.1001/jamanetworkopen.2023.30446
Source: Atherosclerosis - August 23, 2023 Category: Cardiology Authors: Naruchorn Kijpaisalratana Zsuzsanna Ament Matthew B Bevers Varun M Bhave Ana-Lucia Garcia Guarniz Catharine A Couch M Ryan Irvin W Taylor Kimberly Source Type: research
Plasma Trimethylamine- < em > N < /em > -Oxide and Incident Ischemic Stroke: The Cardiovascular Health Study and the Multi-Ethnic Study of Atherosclerosis
Conclusions Plasma TMAO levels are associated with incident ischemic stroke in a diverse population. Registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT00005133.PMID:37581385 | DOI:10.1161/JAHA.122.029230
Source: Atherosclerosis - August 15, 2023 Category: Cardiology Authors: Rozenn N Lemaitre Paul N Jensen Zeneng Wang Amanda M Fretts Colleen M Sitlani Ina Nemet Nona Sotoodehnia Marcia C de Oliveira Otto Weifei Zhu Matt Budoff W T Longstreth Bruce M Psaty David S Siscovick Stanley L Hazen Dariush Mozaffarian Source Type: research
The Gut-Heart Axis: Updated Review for The Roles of Microbiome in Cardiovascular Health
Korean Circ J. 2023 Jun 23. doi: 10.4070/kcj.2023.0048. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs), including coronary artery disease, stroke, heart failure, and hypertension, are the global leading causes of death, accounting for more than 30% of deaths worldwide. Although the risk factors of CVDs have been well understood and various treatment and preventive measures have been established, the mortality rate and the financial burden of CVDs are expected to grow exponentially over time due to the changes in lifestyles and increasing life expectancies of the present generation. Recent advancements in meta...
Source: Korean Circulation Journal - August 1, 2023 Category: Cardiology Authors: Thi Van Anh Bui Hyesoo Hwangbo Yimin Lai Seok Beom Hong Yeon-Jik Choi Hun-Jun Park Kiwon Ban Source Type: research
Atherosclerotic patients with diabetes mellitus may break through the threshold of healthy TMAO levels formed by long-term statins therapy
CONCLUSION: Diabetics have abnormally high plasma TMAO levels even under continuous statins treatment, which may contribute to the development and progression of atherosclerosis. Therefore, it is necessary to focus on monitoring TMAO levels in diabetic patients to reduce adverse cardiovascular events in diabetic patients.PMID:36879744 | PMC:PMC9984437 | DOI:10.1016/j.heliyon.2023.e13657
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Hao Liang Anqi Yu Zheng Wang Na Zhang Qingsong Wang Haichao Gao Junhui Gao Xinjun Wang Hong Wang Source Type: research
The role of gut-dependent molecule trimethylamine N-oxide as a novel target for the treatment of chronic kidney disease
Int Urol Nephrol. 2023 Feb 16. doi: 10.1007/s11255-023-03500-9. Online ahead of print.ABSTRACTTrimethylamine N-oxide (TMAO) is an intestinal uremic toxin molecule mainly excreted by the kidney. Therefore, the plasma TMAO concentration is significantly increased in chronic kidney disease (CKD) patients, and plasma TMAO can be cleared by dialysis. Furthermore, TMAO damage the kidney mainly through three mechanisms: oxidative stress, inflammation and endoplasmic reticulum stress. Clinical experiments have indicated that higher TMAO levels are strongly related to the elevated incidence and mortality of cardiovascular (CV) even...
Source: Atherosclerosis - February 16, 2023 Category: Cardiology Authors: Sai Pan Delong Zhao Shuwei Duan Xiangmei Chen Source Type: research
