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Rate of Change in 10-Year Atherosclerotic Cardiovascular Disease Risk and Its Implications for Primary Prevention
CONCLUSIONS: The temporal change in 10-year ASCVD risk over a period of 4 to 5 years reflects success or failure in controlling major cardiovascular risk factors and indicates the risk of future ASCVD events. The ∆10-year ASCVD risk/year can be used as an indicator of primary prevention and guide the application of preventive measures.PMID:37470768 | DOI:10.1161/HYPERTENSIONAHA.122.20678
Source: Atherosclerosis - July 20, 2023 Category: Cardiology Authors: In-Chang Hwang Chee Hae Kim Jae-Young Kim Hong-Mi Choi Yeonyee E Yoon Goo-Yeong Cho Source Type: research

Recurrent Atherosclerotic Cardiovascular Disease Events Potentially Prevented with Guideline-Recommended Cholesterol-Lowering Therapy following Myocardial Infarction
ConclusionImplementation of guideline-recommended cholesterol-lowering therapy could prevent a substantial percentage of recurrent ASCVD events.
Source: Cardiovascular Drugs and Therapy - April 13, 2023 Category: Cardiology Source Type: research

Association between Low-Density Lipoprotein Cholesterol Level and Cardiovascular Outcomes in Korean Adults: A Nationwide Cohort Study
CONCLUSION: We confirmed the incidence of CVD was increased in higher LDL-C range. The risk of CVD increased from ≥70 mg/dL of LDL-C in very high-risk and high-risk groups, and from ≥130 mg/dL of LDL-C in moderate-risk and low-risk groups in Korean adults.PMID:36727164 | DOI:10.4093/dmj.2021.0320
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Junghyun Noh Min Kyong Moon Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus
CONCLUSION: For primary prevention of CVD in Korean adults with T2DM, it can be helpful to lower LDL-C targets when there are chronic kidney disease, HT, a long duration of diabetes mellitus, or three or more CV risk factors.PMID:36727163 | DOI:10.4093/dmj.2021.0344
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Min Kyong Moon Junghyun Noh Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Association between Low-Density Lipoprotein Cholesterol Level and Cardiovascular Outcomes in Korean Adults: A Nationwide Cohort Study
CONCLUSION: We confirmed the incidence of CVD was increased in higher LDL-C range. The risk of CVD increased from ≥70 mg/dL of LDL-C in very high-risk and high-risk groups, and from ≥130 mg/dL of LDL-C in moderate-risk and low-risk groups in Korean adults.PMID:36727164 | DOI:10.4093/dmj.2021.0320
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Junghyun Noh Min Kyong Moon Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus
CONCLUSION: For primary prevention of CVD in Korean adults with T2DM, it can be helpful to lower LDL-C targets when there are chronic kidney disease, HT, a long duration of diabetes mellitus, or three or more CV risk factors.PMID:36727163 | DOI:10.4093/dmj.2021.0344
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Min Kyong Moon Junghyun Noh Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Evaluating a Simple Approach to Identify Adults Meeting the 2018 AHA/ACC Cholesterol Guideline Definition of Very High Risk for Atherosclerotic Cardiovascular Disease
ConclusionThe vast majority of patients with a recent ACS, history of MI, ischemic stroke, or symptomatic PAD meet the 2018 AHA/ACC cholesterol guideline definition of very high risk.
Source: Cardiovascular Drugs and Therapy - May 19, 2022 Category: Cardiology Source Type: research

Cardiovascular Risk and Treatment Outcomes in Severe Hypercholesterolemia: A Nationwide Cohort Study
Conclusions Using large Korean cohort data, our study proved incrementally elevated cardiovascular risk and clinical benefit associated with LDL-C<100 mg/dL in individuals with severe hypercholesterolemia. These results support aggressive lipid lowering and provide evidence for the LDL-C target in this population.PMID:35470675 | DOI:10.1161/JAHA.121.024379
Source: Atherosclerosis - April 26, 2022 Category: Cardiology Authors: Chan Joo Lee Sanghyun Park Kyungdo Han Sang-Hak Lee Source Type: research

Evaluating a Simple Approach to Identify Adults Meeting the 2018 AHA/ACC Cholesterol Guideline Definition of Very High Risk for Atherosclerotic Cardiovascular Disease
ConclusionThe vast majority of patients with a recent ACS, history of MI, ischemic stroke, or symptomatic PAD meet the 2018 AHA/ACC cholesterol guideline definition of very high risk.
Source: Cardiovascular Drugs and Therapy - March 4, 2021 Category: Cardiology Source Type: research

Mildly Abnormal Lipid Levels, but Not High Lipid Variability, Are Associated with Increased Risk of Myocardial Infarction and Stroke in 'Statin-Naive' Young Population: A Nationwide Cohort Study.
Conclusions: Mildly abnormal baseline lipid levels were associated with an increased future risk of ASCVD events, particularly MI, whereas measures of lipid variability were not. Therefore, in young adults, achieving optimal lipid levels could be valuable in the prevention of ASCVD. PMID: 31978313 [PubMed - as supplied by publisher]
Source: Circulation Research - January 23, 2020 Category: Cardiology Authors: Park JB, Kim D, Lee H, Hwang IC, Yoon YE, Park HE, Choi SY, Kim YJ, Cho GY, Han KD, Kim HK Tags: Circ Res Source Type: research

Efficacy and Safety of High-intensity Statins in Patients with Acute Myocardial Infarction: An Asian Perspective
ConclusionsAMI patients in Taiwan with HIS had similar clinical outcomes to those with non-HIS. Using HIS for effective reduction of low-density lipoprotein cholesterol is safe in Taiwan.
Source: Canadian Journal of Cardiology - November 2, 2019 Category: Cardiology Source Type: research

Statin adherence and persistence on secondary prevention of cardiovascular disease in Taiwan
Conclusions Good adherence and persistence to statin therapy are significantly associated with lower risk of secondary ASCVD rehospitalisation and in-hospital death.
Source: Heart Asia - September 2, 2019 Category: Cardiology Authors: Shau, W.-Y., Lai, C.-L., Huang, S.-T., Chen, S.-T., Li, J. Z., Fung, S., Tse, V. C., Lai, M.-S. Tags: Original research Source Type: research

Cholesterol variability and the risk of mortality, myocardial infarction, and stroke: a nationwide population-based study
ConclusionHigh variability in lipid levels is associated with adverse health-related outcomes. These findings suggest that lipid variability is an important risk factor in the general population.
Source: European Heart Journal - October 21, 2017 Category: Cardiology Source Type: research

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