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Nutrition: Diets
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Total 18 results found since Jan 2013.
The Link between Magnesium Supplements and Statin Medication in Dyslipidemic Patients
Curr Issues Mol Biol. 2023 Apr 5;45(4):3146-3167. doi: 10.3390/cimb45040205.ABSTRACTMany investigations have discovered a connection between statins and magnesium supplements. On one hand, increasing research suggests that chronic hypomagnesemia may be an important factor in the etiology of some metabolic illnesses, including obesity and overweight, insulin resistance and type 2 diabetes mellitus, hypertension, alterations in lipid metabolism, and low-grade inflammation. Chronic metabolic problems seem to be prevented by a high Mg intake combined with diet and/or supplements. On the other hand, it is known that statins low...
Source: Current Issues in Molecular Biology - May 15, 2023 Category: Molecular Biology Authors: Roxana Nartea Brindusa Ilinca Mitoiu Ioana Ghiorghiu Source Type: research
The effect of bempedoic acid an ATP-citrate lyase inhibitor on cardiovascular risk factors in rats with experimentally induced myocardial infarction and hyperlipidemia
Cell Mol Biol (Noisy-le-grand). 2022 Sep 30;68(10):94-99. doi: 10.14715/cmb/2022.68.10.15.ABSTRACTControl of hyperlipidemia is believed to reduce major cardiovascular events such as cardiovascular death, myocardial infarction, nonfatal stroke, hospitalization for unstable angina, and coronary revascularization. The benefits of monotherapy with Bempedoic acid (BA) as a hypolipidemic agent given after induction of myocardial infarction (MI) in reducing the risk of acute MI worth being investigated, therefore this study was designed to investigate the effectiveness of Bempedoic acid on reducing cardiovascular risk factors in ...
Source: Cellular and Molecular Biology - April 28, 2023 Category: Molecular Biology Authors: Mahmood Salim Yaseen Nidhal Mohammed Ali Source Type: research
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases
Mol Neurodegener. 2022 Sep 24;17(1):62. doi: 10.1186/s13024-022-00566-4.ABSTRACTApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of the most influential risk factors for the development of late-onset Alzheimer's disease (AD). Neuroinflammation has become the third hallmark of AD, together with Amyloid-β plaques and neurofibrillary tangles of hyperphosphorylated aggregated tau protein. This review aims to broadly and extensively describe the differential aspects concerning apoE. Starting from the evolut...
Source: Molecular Medicine - September 24, 2022 Category: Molecular Biology Authors: Rosal ía Fernández-Calle Sabine C Konings Javier Fronti ñán-Rubio Juan Garc ía-Revilla Llu ís Camprubí-Ferrer Martina Svensson Isak Martinson Antonio Boza-Serrano Jos é Luís Venero Henrietta M Nielsen Gunnar K Gouras Tomas Deierborg Source Type: research
Impact of hydroxytyrosol on stroke: tracking therapy response on neuroinflammation and cerebrovascular parameters using PET-MR imaging and on functional outcomes
Conclusion: An HT-enriched diet significantly increased the number of Iba-1+ microglia/macrophages in the post-ischemic area, inducing higher expression of anti-inflammatory markers while no clear-cut effect was observed. Also, HT did not affect recovery of the cerebrovascular parameters, including ADC and CBF.Altogether, our data indicated that a prolonged dietary intervention with HT, as a single component of the Mediterranean diet, induces molecular changes that may improve stroke outcomes. Therefore, we support the use of the Mediterranean diet as a multicomponent therapy approach after stroke.
Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Cristina Barca, Maximilian Wiesmann, Jes ú s Calahorra, Lydia Wachsmuth, Christian D ö ring, Claudia Foray, Ali Heiradi, Sven Hermann, Maria Á ngeles Peinado, Eva Siles, Cornelius Faber, Michael Sch ä fers, Amanda J Kiliaan, Andreas H. Jacobs, Bastian Tags: Research Paper Source Type: research
