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Association Between Blood Selenium Levels and Stroke: A Study Based on the NHANES (2011-2018)
Biol Trace Elem Res. 2023 Apr 1. doi: 10.1007/s12011-023-03649-5. Online ahead of print.ABSTRACTAt present, the association between circulating selenium and stroke is still in dispute. Thus, this study aimed to ascertain the association with a larger sample size than the previous study, based on the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2018. In total, 13755 adults over the age of 20 years were included in our study. Multivariate logistic regression models were applied to analyze the correlation between blood selenium levels and stroke. The smooth curve fitting was performed to test the dos...
Source: Biological Trace Element Research - April 2, 2023 Category: Biology Authors: Kunsheng Zhao Yun Zhang Wenhai Sui Source Type: research

BMI Modifies the Association Between Depression Symptoms and Serum Copper Levels
Biol Trace Elem Res. 2022 Nov 27. doi: 10.1007/s12011-022-03505-y. Online ahead of print.ABSTRACTDepression is one of the most common mental disorders which dramatically threatens public health and wellness. Copper has been known to be involved in many biological processes that could help explaining the occurrence of depression. However, studies focusing on its effect have yielded mixed results. The present study aims to evaluate the association between serum copper levels and depression symptoms. It also investigates the effect of modification of BMI (body mass index) on depression symptoms. A total of 5419 US adults aged...
Source: Biological Trace Element Research - November 27, 2022 Category: Biology Authors: Wu Hongrong Li Qingqi Gao Rong Tang Shuangyang Zhang Kaifang Zhao Jianfeng Source Type: research

The role of glutathione peroxidase-1 in health and disease
Free Radic Biol Med. 2022 Jun 9:S0891-5849(22)00224-6. doi: 10.1016/j.freeradbiomed.2022.06.004. Online ahead of print.ABSTRACTGlutathione peroxidase 1 (GPx1) is an important cellular antioxidant enzyme that is found in the cytoplasm and mitochondria of mammalian cells. Like most selenoenzymes, it has a single redox-sensitive selenocysteine amino acid that is important for the enzymatic reduction of hydrogen peroxide and soluble lipid hydroperoxides. Glutathione provides the source of reducing equivalents for its function. As an antioxidant enzyme, GPx1 modulates the balance between necessary and harmful levels of reactive...
Source: Free Radical Biology and Medicine - June 12, 2022 Category: Biology Authors: Diane E Handy Joseph Loscalzo Source Type: research

Comparison of Serum Selenium Levels Between Patients with Newly Diagnosed Atrial Fibrillation and Normal Controls
Biol Trace Elem Res. 2022 May 9. doi: 10.1007/s12011-022-03281-9. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the most common sustained dysrhythmia in the elderly population. It is estimated to affect more than 30 million people worldwide. AF occurs when abnormal electrical impulses start to activate in the atria and override the heart's natural pacemaker, which can no longer control the heart's rhythm. Since atrial contractility is impaired in AF, blood flow in the atria becomes stasis over time and causes thrombus formation. This thrombus causes the risk of embolism and causes complications such as stroke. ...
Source: Biological Trace Element Research - May 8, 2022 Category: Biology Authors: Isa Ardahanli Halil Ibrahim Ozkan Source Type: research

Sex difference in the association between plasma selenium and first stroke: a community-based nested case-control study
ConclusionOur study indicated a significant,non-linear, negative association between plasma selenium and first stroke in males but not in females.Trial registrationChiCTR1800017274.
Source: Biology of Sex Differences - May 29, 2021 Category: Biology Source Type: research

A cross-sectional study of blood selenium concentration and cognitive function in elderly Americans: National Health and Nutrition Examination Survey 2011-2014.
Conclusions: Higher blood selenium is associated with higher cognitive scores in elderly Americans. PMID: 33050724 [PubMed - as supplied by publisher]
Source: Annals of Human Biology - October 21, 2020 Category: Biology Tags: Ann Hum Biol Source Type: research