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Specialty: Cancer & Oncology
Condition: Diabetes
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Total 225 results found since Jan 2013.
Elevated Cardiovascular Disease Risk in Patients With Chronic Myelogenous Leukemia Seen in Community-based Oncology Practices in the United States
Conclusion The increased risk of CVD observed in this real-world analysis of CML patients underscores the importance of current NCCN® recommendations to consider CV risk when selecting TKIs. Teaser Guidelines recommend that comorbidities, including CVD, be considered when selecting TKIs for the treatment of CML. An increased risk of CVD and its risk factors in CML patients treated by community-based US oncologists was identified in a real-world analysis of an EMR database (N=1,639). These results underscore the importance of current NCCN® recommendations to consider CV risk when selecting TKIs.
Source: Clinical Lymphoma Myeloma and Leukemia - June 20, 2017 Category: Cancer & Oncology Source Type: research
Ischemic stroke and intracranial hemorrhage in patients with recurrent glioblastoma multiforme, treated with bevacizumab
AbstractBevacizumab (BVZ), a monoclonal antibody directed against vascular endothelial growth factor (VEGF), has been suspected to increase the incidence of ischemic stroke (IS) and intracranial hemorrhage (ICH) in GBM patients. Intracranial vascular events, such as IS and ICH, were retrospectively analyzed in 364 MRI scans of 82 patients with recurrent GBM (1st/2nd/3rd relapse). Out of these 82 patients, 40 were treated with BVZ (178 scans) in addition to basic treatment, whereas 42 patients matching for age and gender received basic treatment (186 scans). Distribution of typical vascular risk factors between both groups ...
Source: Journal of Neuro-Oncology - May 29, 2017 Category: Cancer & Oncology Source Type: research
Abstract IA22: Using risk assessment tools to motivate behavior change
Epidemiology identifies risk factors for cancer and other diseases based on the idea that conveying such information to healthcare providers, the general public, and policy makers will result in population-wide improvements in healthy behaviors and, consequently, population-wide improvements in health outcomes. These actions assume that the audience understands and uses the information to make health-related decisions. However, the language of epidemiology, which is steeped in probabilistic thinking, is not necessarily the language of the general public. Furthermore, growing evidence suggests that the language of epidemiol...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Waters, E. A. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Oral Presentations - Invited Abstracts Source Type: research
Abstract P6-07-12: A physical activity and dietary counseling intervention in breast cancer survivors and changes in known and novel prognostic biomarkers
High rates of overweight/obesity are commonly seen in breast cancer (BC) survivors. Observational data show an association between post-treatment increased weight and lack of physical activity (PA) and risk of BC recurrence and death. Increases in prognostic inflammatory associated biomarkers (BM) such as interleukin-6 (IL6) and C-reactive protein (CRP), and their downstream effects, are linked to overweight/obesity and provide a potential mechanistic explanation for this increase in recurrence risk, but studies are mixed regarding the effect of lifestyle interventions on these BM. In addition, better BM may exist. The Get...
Source: Cancer Research - February 28, 2017 Category: Cancer & Oncology Authors: LL Peterson, ME Ford, MJ Gregoski, KD Knight, EJ Hilton, G Magwood, DP Turner Tags: Poster Session Abstracts Source Type: research
Abstract P5-08-06: Impact of a decision-support tool on the utilization of colony-stimulating factors and incidence of febrile neutropenia among patients with breast cancer
High rates of overweight/obesity are commonly seen in breast cancer (BC) survivors. Observational data show an association between post-treatment increased weight and lack of physical activity (PA) and risk of BC recurrence and death. Increases in prognostic inflammatory associated biomarkers (BM) such as interleukin-6 (IL6) and C-reactive protein (CRP), and their downstream effects, are linked to overweight/obesity and provide a potential mechanistic explanation for this increase in recurrence risk, but studies are mixed regarding the effect of lifestyle interventions on these BM. In addition, better BM may exist. The Get...
Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: G Adeboyeje, A Agiro, A Goodwin, A DeVries, J Malin Tags: Poster Session Abstracts Source Type: research
Abstract PD4-07: Are aromatase inhibitors associated with higher myocardial infarction risk in breast cancer patients? A Medicare population study
Conclusions: The occurrence of MI is very low in this cohort (4.4%), reassuring the clinicians that the older adults with comorbidities may not be at a higher risk of MI with adjuvant endocrine therapy. However, the confidence interval for the hazard ratio of AIs vs Tamoxifen is very wide, indicating that a larger sample may be needed for the power of the study to be conclusive.Citation Format: Kamaraju S, Smith E, Shi Y, Laud P, Neuner J. Are aromatase inhibitors associated with higher myocardial infarction risk in breast cancer patients? A Medicare population study [abstract]. In: Proceedings of the Thirty-Ninth Annual C...
Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: S Kamaraju, E Smith, Y Shi, P Laud, J Neuner Tags: Poster Discussion Abstracts Source Type: research
Abstract B16: Comparing heart age among Alabama residents with and without a history of cancer
Conclusion: Among the sample of 8,153 Alabama residents, cancer survivors have significantly higher heart age score, suggestive of greater risk for developing cardiovascular disease than residents with no history of cancer. Additional analyses will include exploring decision tree and logistic regression models to predict cancer diagnosis. Disparities in race, age, socioeconomic status, and geographic locations will be explored. Future research includes developing interventions to reduce the cardiovascular risk among cancer survivors.Acknowledgments: This study was approved by the University of Alabama at Birmingham Institu...
Source: Cancer Epidemiology Biomarkers and Prevention - February 4, 2017 Category: Cancer & Oncology Authors: Bui, J., Raju, D., Landier, W., Kenzik, K., Scarabelli, T., Meneses, K. Tags: Novel Technologies: Poster Presentations - Proffered Abstracts Source Type: research
The right to be forgotten: a change in access to insurance and loans after childhood cancer?
ConclusionThis study showed that the financial burden of cancer can extend decades after diagnosis.Implications for Cancer SurvivorsThanks to a 2016 law, French cancer survivors no longer have to disclose their cancer to insurers after a fixed number of years. This law will probably lessen the socioeconomic burden of cancer.
Source: Journal of Cancer Survivorship - January 26, 2017 Category: Cancer & Oncology Source Type: research
Relation between baseline plaque features and subsequent coronary artery remodeling determined by optical coherence tomography and intravascular ultrasound.
We examined the influence of baseline plaque characteristics on subsequent vascular remodeling in response to changes in plaque size. Using optical coherence tomography (OCT) and intravascular ultrasound (IVUS), we examined 213 plaques from 138 patients with acute coronary syndrome at baseline and repeated IVUS at the 12-month follow-up. The change in external elastic membrane (EEM) area for each 1 mm2 change in plaque area (i.e., the slope of the regression line) was calculated as a measure of vascular remodeling capacity. In plaques with static positive remodeling, the slope was smaller than in plaques without static pos...
Source: Oncotarget - December 20, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research
The effect of the severity of obstructive sleep apnea syndrome on telomere length.
In conclusion, our study indicates the presence of an association between LTL and OSAS and a significant impact of severity of OSAS in telomeres shortening.
PMID: 27690344 [PubMed - as supplied by publisher]
Source: Oncotarget - October 2, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research
How Your Diet May Affect Your Risk of Breast Cancer
By Stacy SimonHave you ever said “no thanks” to a tempting dessert or eaten only salad for lunch because you were trying to cut back? If so, you’re among many women who try every day to protect their health by eating right. The American Cancer Society recommends eating mostly vegetables, fruits, and whole grains, and less red meat (beef, pork, and lamb), less processed meat (bacon, sausage, luncheon meats, and hot dogs), and fewer sweets. A healthy diet can help reduce the risk of heart disease, diabetes, stroke, and certain cancer types.A healthy diet can also help you get to and stay at a healthy weight...
Source: American Cancer Society :: News and Features - September 30, 2016 Category: Cancer & Oncology Tags: Breast Cancer Diet/Exercise/Weight Prevention/Early Detection Source Type: news
Lifestyle factors and prostate-specific antigen (PSA) testing in UK Biobank: Implications for epidemiological research
Conclusions A variety of sociodemographic, lifestyle and health-related characteristics are associated with PSA testing, suggesting that observed associations of some of these traits with risk for prostate cancer in epidemiological studies may be, at least partially, due to detection bias.
Source: Cancer Epidemiology - September 29, 2016 Category: Cancer & Oncology Source Type: research
Say Yes to Yoga
By Stacy SimonThe ancient Indian practice of yoga combines meditation, breathing, and precise postures and poses to make a connection with thoughts, body, and spirit. People who practice yoga claim it leads to a state of physical health, relaxation, happiness, peace, and tranquility.Some evidence shows that yoga can lower stress, increase strength, and lessen lower back pain, while providing exercise. And according to a report from the National Institutes of Health, there is also some evidence to suggest yoga may be helpful when used alongside conventional medical treatment to help relieve some of the symptoms linked to ca...
Source: American Cancer Society :: News and Features - September 1, 2016 Category: Cancer & Oncology Tags: Complementary and Alternative Methods Source Type: news
Regular Exercise: Antidote for Deadly Diseases?
High levels of physical activity linked to lower risk for two cancers, diabetes, heart disease and stroke
Source: Cancercompass News: Breast Cancer - August 10, 2016 Category: Cancer & Oncology Source Type: news
