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Specialty: Internal Medicine
Condition: Cholesterol

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Total 164 results found since Jan 2013.

Safeguarding Against Stroke Risk by Statins
Whereas mighty prospective randomized trials —and meta-analyses of these—rightly command the data used to drive guidelines and daily clinical practice, careful long-term follow-up of closely monitored cohorts can generate crucial discoveries not anticipated in a 5-year study. As just one example, findings from lifelong follow-up in the Ame rican Framingham studies and the Whitehall cohorts in the United Kingdom show a strong association between blood pressure in middle years and dementia in later life.
Source: Mayo Clinic Proceedings - September 1, 2023 Category: Internal Medicine Authors: Adrian J.B. Brady Tags: Editorial Source Type: research

Dyslipidemia
Ann Intern Med. 2023 Jun 13. doi: 10.7326/AITC202306200. Online ahead of print.ABSTRACTDyslipidemia is an important risk factor for coronary artery disease and stroke. All persons with dyslipidemia should be advised to focus on lifestyle interventions, including regular aerobic exercise, a healthy diet, maintenance of a healthy weight, and abstinence from smoking. In addition to lifestyle interventions, lipid-lowering therapy should be considered for persons at moderate to high risk for atherosclerotic cardiovascular disease based on validated risk equations. Statin therapy is the first-line medical treatment for dyslipide...
Source: Annals of Internal Medicine - June 12, 2023 Category: Internal Medicine Authors: Marios Arvanitis Charles J Lowenstein Source Type: research

Immediate Statin After Acute Stroke Reduces Disability Immediate Statin After Acute Stroke Reduces Disability
Intensive statin therapy immediately after mild ischemic stroke or high-risk TIA reduces the risk for a poor functional outcome vs delaying 72 hours, the INSPIRES trial shows.Medscape Medical News
Source: Medscape Internal Medicine Headlines - June 9, 2023 Category: Internal Medicine Tags: Neurology & Neurosurgery News Source Type: news

Association of non-HDL-C-to-HDL-C ratio with coronary lesions and its prognostic performance in first-onset NSTEMI
Conclusion: NON-HDL-C:HDL-C is associated with coronary lesions and prognosis in non-ST-segment elevation acute myocardial infarction.PMID:36994674 | DOI:10.2217/bmm-2022-0548
Source: Future Medicine: Biomarkers in Medicine - March 30, 2023 Category: Internal Medicine Authors: Qi Mao Jianhua Zhao Xiaohui Zhao Source Type: research

Research on Hepatocyte Regulation of PCSK9-LDLR and Its Related Drug Targets
AbstractThe prevalence of hyperlipidemia has increased significantly due to genetic, dietary, nutritional and pharmacological factors, and has become one of the most common pathological conditions in humans. Hyperlipidemia can lead to a range of diseases such as atherosclerosis, stroke, coronary heart disease, myocardial infarction, diabetes, and kidney failure, etc. High circulating low-density lipoprotein cholesterol (LDL-C) is one of the causes of hyperlipidemia. LDL-C in the blood binds to LDL receptor (LDLR) and regulates cholesterol homeostasis through endocytosis. In contrast, proprotein convertase subtilisin/kexin ...
Source: Chinese Journal of Integrative Medicine - March 13, 2023 Category: Internal Medicine Source Type: research

Comparative effectiveness of acupuncture and pharmacological interventions in treating diabetic stroke: A protocol for a systematic review and network meta-analysis
Conclusion: The results will systematically provide suggestions for medical practitioners to choose the effective, time-saving and economical therapeutic strategy for diabetic stroke.
Source: Medicine - November 18, 2022 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

The prevention of stroke by statins: A meta-analysis
Conclusions: Our findings indicated that the statins were associated with the patients with stroke in recurrence rate, but there was no significant correlation with the mortality and morbidity of patients with stroke.
Source: Medicine - September 23, 2022 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research