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Saving Vanessa, part 1: A mystery rash, a stroke and an epic rescue
Vanessa’s rash first appeared on her arms and legs when she 3 or 4 months old. It was red and bumpy and went away when she was sick with a virus, which happened often. Then it would come back. The dermatology team she saw at Boston Children’s Hospital was puzzled. “I was expecting they were going to think it was nothing, but they took it very seriously,” says Katherine Bell, one of Vanessa’s mothers. “They took a biopsy and very quickly realized they had no idea what it was.” Vanessa’s case was even featured at a regional dermatology conference where doctors take up mystery patients. “A hundred to 150 der...
Source: Thrive, Children's Hospital Boston - July 25, 2017 Category: Pediatrics Authors: Nancy Fliesler Tags: Diseases & Conditions Our Patients’ Stories Dr. Carolyn Rogers Dr. Pui Lee Dr. Robert Sundel Dr. Scellig Stone Dr. Todd Lyons stroke Source Type: news

Duke to Participate in Early Clinical Trials for Emerging Neurological Therapies
Contact: Samiha Khanna Phone: 919-419-5069 Email: samiha.khanna@duke.edu https://www.dukehealth.org FOR IMMEDIATE RELEASE on Thursday, July 21, 2016 DURHAM, N.C. -- Duke University could receive up to $19 million to lead early-stage clinical trials for new drugs to treat neurological conditions such as Alzheimer ’s disease and neuropathy. The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, awarded the 10-year contract to Duke to design, manage, and conduct Phase I clinical trials. The trials will be conducted at the Duke Clinical Research Unit (DCRU), the earl...
Source: DukeHealth.org: Duke Health Features - July 21, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Multimodal Outcome at 7 Years of Age after Neonatal Arterial Ischemic Stroke
To evaluate the epileptic, academic, and developmental status at age 7 years in a large population of term-born children who sustained neonatal arterial ischemic stroke (NAIS), and to assess the co-occurrence of these outcomes.
Source: The Journal of Pediatrics - March 9, 2016 Category: Pediatrics Authors: Stéphane Chabrier, Emeline Peyric, Laure Drutel, Johanna Deron, Manoëlle Kossorotoff, Mickaël Dinomais, Leila Lazaro, Jérémie Lefranc, Guillaume Thébault, Gérard Dray, Joel Fluss, Cyrille Renaud, Sylvie Nguyen The Tich, Accident Vasculaire Cérébr Tags: Original Article Source Type: research

Low Predictability of Three Different Noninvasive Methods to Determine Fluid Responsiveness in Critically Ill Children
Conclusions: Dynamic preload variables such as stroke volume variation or respiratory variations in vena cava inferior diameter may not be useful for predicting fluid responsiveness in certain pediatric patient populations. Esophageal Doppler peak velocity was predictive of fluid responsiveness where a target value of more than 135,5 cm/s may be a signal to terminate further fluid challenges. This target value may be different in different age groups, as esophageal Doppler peak velocity varies with age.
Source: Pediatric Critical Care Medicine - March 1, 2015 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Freedom in waiting: A ventricular assist device gives Aidan’s family independence
Aidan When Aidan was just 8 months old, his parents Patrick and Tavina received shocking news—their son had hypertrophic cardiomyopathy, a rare but serious disease that affects the muscle of the heart. Given his young age and severity of his condition, the early prognosis was bleak. “Things didn’t look good at first,” remembers Patrick. “We were steeling ourselves for the real possibility that Aidan wouldn’t make it to see his first birthday.” But, heart condition or not, little Aidan was a fighter, and with minimal medical management his condition stabilized. Over the years, he grew ...
Source: Thrive, Children's Hospital Boston - July 3, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Heart conditions Our patients’ stories Christina VanderPluym Heart Center heart transplant hypertrophic cardiomyopathy MD VAD ventricular assist device Source Type: news