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Specialty: Neurology
Condition: Atrial Fibrillation

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Total 2086 results found since Jan 2013.

No sex difference was found in the safety and efficacy of intravenous alteplase before endovascular therapy
ConclusionOur study could not confirm that sex modifies the treatment effect of intravenous alteplase before endovascular therapy. At the same time, we advocate for women to seek timely medical treatment.
Source: Frontiers in Neurology - November 9, 2022 Category: Neurology Source Type: research

Comparison of primary and secondary stroke prevention in patients with nonvalvular atrial fibrillation: Results from the RAFFINE registry
Atrial fibrillation (AF) is a predictor of severe stroke and early death in acute ischemic stroke patients.1 The prevalence of AF has increased as the Japanese population has aged.2 AF has been more common among patients with ischemic stroke than previously reported.3 In particular, AF patients with a history of stroke or TIA have had higher risks for stroke, hemorrhagic events, and death compared to those without.4,5 In these previous studies, most patients received warfarin for anticoagulation therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - November 7, 2022 Category: Neurology Authors: Kazuo Yamashiro, Ryota Tanaka, Sakiko Miyazaki, Katsumi Miyauchi, Hidemori Hayashi, Yuji Nishizaki, Shuko Nojiri, Satoru Suwa, Masataka Sumiyosi, Yuji Nakazato, Takao Urabe, Nobutaka Hattori, Tohru Minamino, Hiroyuki Daida Source Type: research

Early diagnosis of intracranial atherosclerotic large vascular occlusion: A prediction model based on DIRECT-MT data
ConclusionOur current prediction model based on clinical data of patients from the DIRECT-MT trial might be a promising tool for predicting ICAS-LVO.
Source: Frontiers in Neurology - November 3, 2022 Category: Neurology Source Type: research

Effect of mean heart rate on 30-day mortality in ischemic stroke with atrial fibrillation: Data from the MIMIC-IV database
ConclusionIn this retrospective cohort study, MHR within 24 h of admission was associated with 30-day mortality (nonlinear, J-shaped association) in patients with ischemic stroke and atrial fibrillation in the ICU, with an inflection point at about 80 bpm and a minimal risk observed at 72 to 81 bpm of MHR. This association was worthy of further investigation. If further confirmed, this association may provide a theoretical basis for formulating the target strategy of heart rate therapy for these patients.
Source: Frontiers in Neurology - October 31, 2022 Category: Neurology Source Type: research

Excessive supraventricular ectopic activity and future onset of atrial fibrillation in patients with cryptogenic stroke
Although atrial fibrillation (AF) is a leading preventable cause of ischemic stroke,1,2 after the initial evaluation, approximately 30% of all stroke events are finally characterised as cryptogenic.3,4 However, nowadays with the use of prolonged cardiac rhythm monitoring, studies exist to reveal the existence of silent, subclinical AF in those patients, or even the presence of excessive ectopic atrial activity that may precede it.5,6 In particular, such methods can detect and quantify premature atrial complexes (PACs) and short supraventricular runs (SVRs), which, up until recently, have been considered benign electrophysiological phenomena.
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2022 Category: Neurology Authors: Christos Gogos, Elias Zarvalis, Panteleimon Pantelidis, Foteini Davora, Asterios Karakanas, Dimitrios Pitetzis, Nikolaos Stamatiadis, Vasileios Moschovidis, Melani Konstantinidou, Evangelos Oikonomou, Georgia Deretzi, Jobst Rudolf, Ioannis Styliadis Source Type: research

Neurogenic cardiac outcome in patients after acute ischemic stroke: The brain and heart connection
This study aims to identify the association between cardiac outcomes and middle cerebral artery (MCA) ischemic stroke, with or without insular cortex involvement, as well as the impact of new-onset atrial fibrillation (AF) after AIS on recurrent stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 28, 2022 Category: Neurology Authors: Jiangyong Min, Grant Young, Abdullah Umar, Andrew Kampfschulte, Asad Ahrar, Malgorzata Miller, Nadeem Khan, Nabil Wees, Nagib Chalfoun, Muhib Khan Tags: Review Article Source Type: research

Association of blood-based biomarkers with radiologic markers and cognitive decline in atrial fibrillation patients
Atrial fibrillation (AF) has been associated with an increased risk of silent brain infarcts (SBI) and cognitive impairment, even in patients with low embolic risk. We aimed to test the association between 11 blood-biomarkers representing different AF-related pathways, and SBI, white matter hyperintensities (WMH), and cognitive decline in patients with AF and low embolic risk.
Source: Journal of Stroke and Cerebrovascular Diseases - October 26, 2022 Category: Neurology Authors: Elena Pal à, Irene Escudero-Martínez, Anna Penalba, Alejandro Bustamante, Marcel Lamana-Vallverdú, Fernando Mancha, Rafael F. Ocete, Pilar Piñero, Alejandro Galvao-Carmona, Marta Gómez-Herranz, Soledad Pérez-Sánchez, Francisco Moniche, Alejandro Go Source Type: research

Error in Text
The Original Investigation “Severity and Etiology of Incident Stroke in Patients Screened for Atrial Fibrillation vs Usual Care and the Impact of Prior Stroke: A Post Hoc Analysis of the LOOP Randomized Clinical Trial,” published online August 29, 2022, had an error in the Statistical Analysis section of the text. The cut off for statistical significance should read P< .05 rather than P> .05. This error has been corrected online.
Source: JAMA Neurology - October 17, 2022 Category: Neurology Source Type: research

Holter ECG monitoring for the evaluation of stroke in the internal medicine department
Holter ECG is an external device for cardiac monitoring, connected by electrodes to the patient. The Holter performs a continuous recording of the cardiac electrical activity, which is used to reveal an underling arrhythmia.1 Diagnosing an arrythmia among stroke patients, especially atrial fibrillation/flutter (AF), is of significant influence, indicating a hypothetic cardio-embolic source with increased risk of recurrent stroke.2 –4 Once AF is found, anticoagulant therapy, rather than antiplatelet therapy, is recommended for secondary stroke prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2022 Category: Neurology Authors: Inbar Caspi, Ophir Freund, Roni Biran, Gil Bornstein Tags: Short Communication Source Type: research

A nomogram for predicting atrial fibrillation detected after acute ischemic stroke
ConclusionPredictive models based on clinical characteristics, laboratory variables, and neuroimaging variables showed good calibration and high net clinical benefit, informing clinical decision-making in diagnosing and treating patients with AFDAS.
Source: Frontiers in Neurology - October 14, 2022 Category: Neurology Source Type: research

Safety of Apixaban Monotherapy for Non-Valvular Atrial Fibrillation-Related Acute Stroke with Intra-/Extracranial Artery Stenosis
Conclusion: Apixaban monotherapy appears safe for the prevention of further adverse events in the Stenosis group patients similar to the No stenosis group patients. Concomitant use of an antiplatelet might not be favorable in patients with stenosis.Cerebrovasc Dis
Source: Cerebrovascular Diseases - October 12, 2022 Category: Neurology Source Type: research

Broadening Our SCOPE of Understanding Patent Foramen Ovale High-risk Features and Stroke
Paradoxical embolization of a blood clot of presumed venous origin through a patent foramen ovale (PFO) is increasingly recognized as a legitimate cause of otherwise cryptogenic ischemic stroke (CIS). The term PFO-associated stroke has been proposed, as has where and how to classify this entity in the nomenclature of various ischemic stroke subtyping systems. PFOs are common, with prevalence as high as 25% in the general population. The prevalence of PFO is further increased in patients with CIS (overall 2.9 times higher), and especially so in the subset of younger patients (<55 years, 5.1 times higher). One estimate of...
Source: JAMA Neurology - October 10, 2022 Category: Neurology Source Type: research

AF an Independent Risk Factor for Poor Outcomes in Ischemic Stroke AF an Independent Risk Factor for Poor Outcomes in Ischemic Stroke
A retrospective study suggests that atrial fibrillation (AF) is an independent risk factor for severe ischemic stroke and increased inpatient mortality rates.First Look
Source: Medscape Neurology and Neurosurgery Headlines - October 5, 2022 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

The relationship between vertebrobasilar artery calcification and intracranial atherosclerosis-related occlusion in thrombectomy
ConclusionsWe demonstrated that VBAC is an independent risk factor for ICAS-O in patients who underwent thrombectomy. Patients free of atrial fibrillation with VBAC have more trend to be ICAS-O.
Source: Frontiers in Neurology - October 4, 2022 Category: Neurology Source Type: research

Atrial fibrillation is associated with poor long-term outcome after mechanical thrombectomy for anterior large vessel occlusion stroke
Atrial fibrillation (AF) is one of the leading causes of acute ischemic stroke (AIS). The aim of our study was to determine the influence of AF on the long-term outcome of patients with AIS due to anterior circulation large vessel occlusion (LVO) treated with mechanical thrombectomy (MT).
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2022 Category: Neurology Authors: Mirjana Ždraljević, Tatjana Pekmezović, Predrag Stanarčević, Ivan Vukašinović, Ivana Berisavac, Marko Ercegovac, Filip Vitošević, Dragoslav Nestorović, Vladimir Cvetić, Višnja Padjen, Maja Stefanović-Budimkić, Tamara Švabić Medjedović, De Source Type: research