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Specialty: Neurology
Condition: Ischemic Stroke

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Total 20790 results found since Jan 2013.

Left ventricular hypertrophy and left atrial size are associated with ischemic strokes among non-vitamin K antagonist oral anticoagulant users
ConclusionsPrior cerebrovascular events, diabetes, left ventricular hypertrophy, and increased left atrial size are risk factors for developing an IS among NOAC users.
Source: Journal of Neurology - August 7, 2023 Category: Neurology Source Type: research

Transient ischemic attack and minor stroke as “surgeons affairs”: a narrative review
ConclusionsTIA and mS require a multidisciplinary in order to discuss therapeutic options, comparing risks and benefits and determining the best timing for an optimized management.
Source: Neurological Sciences - August 5, 2023 Category: Neurology Source Type: research

Monitoring Risk and Preventing Ischemic Stroke in the Very Old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rubin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research

METTL14 regulates microglia/macrophage polarization and NLRP3 inflammasome activation after ischemic stroke by the KAT3B-STING axis
Neurobiol Dis. 2023 Aug 2:106253. doi: 10.1016/j.nbd.2023.106253. Online ahead of print.ABSTRACTN6-methyladenosine (m6A) plays a crucial role in ischemic stroke, whereas the role of methyltransferase-like 14 (METTL14) in ischemic stroke remains unknown. A model of middle cerebral artery occlusion (MCAO) in rats and oxygen-glucose deprivation/reperfusion (OGD/R) model in HAPI cells were used to simulate ischemic stroke in vivo and in vitro. We found that METTL14 level was upregulated in microglia/macrophage after MCAO and OGD/R. METTL14 enhanced the expression of KAT3B by promoting the m6A modification of KAT3B mRNA. STING ...
Source: Neurobiology of Disease - August 4, 2023 Category: Neurology Authors: Yamei Li Jiacen Li Qian Yu Ling Ji Bo Peng Source Type: research

Frequency, characteristics, and predictors of headache attributed to acute ischemic stroke
CONCLUSION: Pre-existing headache disorder, fever, and posterior circulation stroke were associated with headache occurrence in acute ischemic stroke patients.PMID:37541931 | DOI:10.1016/j.neurol.2023.03.022
Source: Revue Neurologique - August 4, 2023 Category: Neurology Authors: M Hussein M Ali M Abdelghaffar A Yassien R Gomaa R Assad R Magdy Source Type: research

METTL14 regulates microglia/macrophage polarization and NLRP3 inflammasome activation after ischemic stroke by the KAT3B-STING axis
Neurobiol Dis. 2023 Aug 2:106253. doi: 10.1016/j.nbd.2023.106253. Online ahead of print.ABSTRACTN6-methyladenosine (m6A) plays a crucial role in ischemic stroke, whereas the role of methyltransferase-like 14 (METTL14) in ischemic stroke remains unknown. A model of middle cerebral artery occlusion (MCAO) in rats and oxygen-glucose deprivation/reperfusion (OGD/R) model in HAPI cells were used to simulate ischemic stroke in vivo and in vitro. We found that METTL14 level was upregulated in microglia/macrophage after MCAO and OGD/R. METTL14 enhanced the expression of KAT3B by promoting the m6A modification of KAT3B mRNA. STING ...
Source: Neurobiology of Disease - August 4, 2023 Category: Neurology Authors: Yamei Li Jiacen Li Qian Yu Ling Ji Bo Peng Source Type: research

Monitoring Risk and Preventing Ischemic Stroke in the Very Old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rubin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research

Frequency, characteristics, and predictors of headache attributed to acute ischemic stroke
CONCLUSION: Pre-existing headache disorder, fever, and posterior circulation stroke were associated with headache occurrence in acute ischemic stroke patients.PMID:37541931 | DOI:10.1016/j.neurol.2023.03.022
Source: Revue Neurologique - August 4, 2023 Category: Neurology Authors: M Hussein M Ali M Abdelghaffar A Yassien R Gomaa R Assad R Magdy Source Type: research

Monitoring Risk and Preventing Ischemic Stroke in the Very Old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rubin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research