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Total 1481 results found since Jan 2013.

Is there a bidirectional relationship between stroke risk and mood disorders in older adult patients?
Research suggests that there may be a causal relationship between stroke and depression symptoms. However, the direction of this relationship remains unclear, which suggests the possibility that it is bidirectional.   Indeed, some findings suggest that depression is a common occurrence post-stroke and that individuals who have a greater stroke risk are also more likely to have depression. Conversely, there is also evidence that depression may be a risk factor for stroke. In addition, although most of the liter ature focuses on the relationship between cardiovascular health and depression, less is known about other mood di...
Source: The American Journal of Geriatric Psychiatry - February 17, 2023 Category: Geriatrics Authors: Ana Trueba, Boyu Ren, Regan E. Patrick, David G. Harper, Brent P. Forester Tags: Poster Number: NR-10 Source Type: research

Predictors of short‐ and long‐term mortality in first‐ever ischaemic older stroke patients
ConclusionsNIHSS score on admission, age and coronary heart disease are independent predictors of short‐ and long‐term mortality. Higher glucose and lower triglyceride level are significantly associated with the long‐term mortality.
Source: Australasian Journal on Ageing: - March 1, 2013 Category: Geriatrics Authors: Chia‐Yu Hsu, Gwo‐Chi Hu, Yi‐Min Chen, Chiu‐Hsiang Chen, Yu‐Ning Hu Tags: Brief Report Source Type: research

Abnormal levels of brain metabolites may mediate cognitive impairment in stroke-free patients with cerebrovascular risk factors
Conclusion: abnormal concentrations of brain metabolites and decreased glutamate plus glutamine concentration may play an important role in the pathophysiology of VRF-associated cognitive impairment. Brain metabolites detected by 1H MRS may serve as important markers for monitoring VRFs burden.
Source: Age and Ageing - August 25, 2014 Category: Geriatrics Authors: Sun, D., Zhang, J., Fan, Y., Liu, X., Gao, Y., Wu, G., Yan, Y., Zeng, J. Tags: Research Papers Source Type: research

A very unusual organism causing stroke-like symptoms
A 78-year-old man presented to hospital with new onset confusion and fever. The working diagnosis was of delirium due to an infection of unknown source, and empirical i.v. antibiotic treatment was given. Two days later, he deteriorated and developed clinical features in keeping with a total anterior circulation stroke. Brain imaging was unremarkable. Blood cultures grew an organism subsequently identified as Facklamia languida. Following treatment with broad-spectrum antibiotics, his condition improved. A diagnosis of F. languida septicaemia, leading to presumed (unwitnessed) seizure and Todd's paresis was made. The patien...
Source: Age and Ageing - August 25, 2014 Category: Geriatrics Authors: McCann, E., Barber, M., Hunter, P., Inverarity, D. Tags: Case Reports Source Type: research

Secondary Prevention of Stroke in the Elderly: Focus on Drug Therapy
Abstract Secondary stroke prevention in the elderly in many cases requires the use of drug therapy to maximize risk factor control. However, the elderly (≥65 years) are most likely to receive care that is not evidence-based, because of concerns for adverse events. In this review, we provide evidence to the practitioner in support of the value of blood pressure control with drug therapy to decrease recurrent stroke risk. This review also highlights evidence for the importance of statin therapy in stroke prevention among the elderly. Finally, the appropriate use of antiplatelet therapy and oral anticoagulation is addressed.
Source: Drugs and Aging - September 29, 2014 Category: Geriatrics Source Type: research

Identification of diabetes, heart disease, hypertension and stroke in mid‐ and older‐aged women: Comparing self‐report and administrative hospital data records
ConclusionSubstantial agreement was found for diabetes, indicating accuracy of ascertainment using self‐report or hospital data. Self‐report data appears to be less accurate for heart disease and stroke. Hypertension was underestimated in hospital data. These findings have implications for epidemiological studies relying on self‐report or administrative data. Geriatr Gerontol Int 2015; ●●: ●●–●●.
Source: Geriatrics and Gerontology International - January 22, 2015 Category: Geriatrics Authors: Tina J Navin Cristina, Jennifer A Stewart Williams, Lynne Parkinson, David W Sibbritt, Julie E Byles Tags: Original Article: Epidemiology, Clinical Practice and Health Source Type: research

An abbreviated German version of the Sense of Competence Questionnaire among informal caregivers of relatives who had a stroke: development and validation
In this study, we evaluated the psychometric properties of the German version of the SCQ with informal caregivers of stroke patients. Baseline data of a randomized controlled trial (n = 122) and survey data (n = 76) of caregivers of stroke patients were used. Data were collected at the caregiver’s or the care receiver’s home or over the telephone. We evaluated the homogeneity, the construct validity, and the clinical validity of the German version and the homogeneity of a new abbreviated version. The homogeneity of the SCQ indicates good reliability (Cronbach’s alpha: 0.89). The three-factor structure of the SCQ ...
Source: European Journal of Ageing - April 1, 2015 Category: Geriatrics Source Type: research

Factors Influencing Non-Persistence with Antiplatelet Medications in Elderly Patients After Ischaemic Stroke
Conclusions Our results suggest that women, patients aged <75 years, and patients without certain comorbid conditions may need improved assistance in secondary prevention management after an ischaemic stroke.
Source: Drugs and Aging - March 28, 2016 Category: Geriatrics Source Type: research

Cognition in relation to independency in older, comorbid stroke patients in a stroke unit
ConclusionFrom a clinical point of view, we suggest combining physical and cognitive training from the very early phase of recovery.
Source: International Journal of Geriatric Psychiatry - May 31, 2016 Category: Geriatrics Authors: Marleen Huijben‐Schoenmakers, Arno Rademaker, Erik Scherder Tags: Research Article Source Type: research

The Challenge of Altered Sexual Function in Stroke Survivors Undergoing Rehabilitation
The occurrence of a stroke brings about an abrupt change in the life situation for the individual and immediate family members. The physical impairments and emotional responses that follow a stroke have profound effects that impact everyday living, interpersonal relationships, intimacy, and sexuality. Numerous studies have shown that individuals report a marked decline in sexual function after a stroke. The focus of this study is on the pathophysiological and emotional factors that contribute to this decline and how these factors are evaluated and managed by health professionals during the phase of early poststroke rehabilitation.
Source: Topics in Geriatric Rehabilitation - July 1, 2016 Category: Geriatrics Tags: Sex in the Second Half: Vibrant and Healthy Sexual Aging Source Type: research

Higher skeletal muscle mass may protect against ischemic stroke in community-dwelling adults without stroke and dementia: The PRESENT project
It is well known that a low skeletal muscle mass (SMM) is associated with stroke. However, it is unknown whether increasing muscle mass can prevent stroke.
Source: BMC Geriatrics - February 3, 2017 Category: Geriatrics Authors: Yang-Ki Minn and Seung-Han Suk Source Type: research

Real ‐World Clinical Characteristics and Treatment Patterns of Individuals Aged 80 and Older with Nonvalvular Atrial Fibrillation: Results from the ReAl‐life Multicenter Survey Evaluating Stroke Study
ConclusionNearly one‐fifth of individuals with NVAF in this real‐world sample were aged 80 and older. Participants aged 80 and older were more likely to be female and have more comorbidities than those who were younger than 80. Those aged 80 and older with AF were less likely to receive anticoagulants than those who were younger than 80, but having more comorbidities and other individual‐level characteristics may explain this difference. When they were prescribed OACs, participants aged 80 and older had poorer quality of anticoagulation than those who were younger, suggesting opportunities for improvement.
Source: Journal of the American Geriatrics Society - April 10, 2017 Category: Geriatrics Authors: Murat Biteker, Özcan Başaran, Volkan Doğan, İbrahim Altun, Fatma Özpamuk Karadeniz, Ahmet İlker Tekkesin, Yasin Çakıllı, Ceyhan Türkkan, Mehmet Hamidi, Vahit Demir, Mustafa Ozan Gürsoy, Müjgan Tek Öztürk, Gökhan Aksan, Sabri Seyis, Mehmet B Tags: Clinical Investigation Source Type: research

Associations of Tumor Necrosis Factor –α and Interleukin-1β Levels and Polymorphisms with Post-Stroke Depression
Depression frequently occurs in patients with stroke.1 This common comorbidity may be due to the shared biological etiologies of the two disorders, one of which is referred to as the cytokine hypothesis.2 Stroke induces inflammatory reactions, including changes in cytokine activity.3 Proinflammatory cytokines, such as tumor necrosis factor (TNF)- α, interleukin (IL)-1, and IL-6, have been implicated in the initiation and/or amplification of the inflammatory response during acute stroke pathophysiology.
Source: The American Journal of Geriatric Psychiatry - July 25, 2017 Category: Geriatrics Authors: Jae-Min Kim, Hee-Ju Kang, Ju-Wan Kim, Kyung-Yeol Bae, Sung-Wan Kim, Joon-Tae Kim, Man-Seok Park, Ki-Hyun Cho Tags: Regular Research Articles Source Type: research

Selected Factors Against Functional Performance in Patients in the Early Period After Stroke
The main objective of the study was to evaluate the impact of selected clinical factors on functional performance in 693 patients in the early period after stroke. The level of functional performance of each patient was evaluated twice (before and after 4 weeks of rehabilitation) using the short version of the Barthel Index. A comprehensive 4-week rehabilitation program significantly improved the functional performance of stroke survivors (P = .0001). There was no significant relationship between functional improvement and age (P = .3800), sex (P = .4085), type of stroke (P = .7498), and side of paresis (P = .1573).
Source: Topics in Geriatric Rehabilitation - October 1, 2017 Category: Geriatrics Tags: Thieves' Market Source Type: research

Post-Stroke Cognitive Impairment, Depression and Apathy: Untangling the Relationship
Neurobehavioral researchers have long decried the neglect of the neuropsychiatric consequences of stroke in favor of the classical emphasis on motor and speech deficits [1]. In the last three decades, the situation has steadily changed, with increasing emphasis on post-stroke cognitive impairment [2] and depression [3]. Much less attention has been paid to apathy, which occurs about as frequently as cognitive impairment and depression after stroke [4], and has a major impact on both the patient and significant others [5].
Source: The American Journal of Geriatric Psychiatry - December 11, 2017 Category: Geriatrics Authors: Perminder S. Sachdev Tags: Invited Perspective Source Type: research