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Specialty: Geriatrics
Nutrition: Vitamins
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Total 25 results found since Jan 2013.
Safety outcomes of direct oral anticoagulants in older adults with atrial fibrillation: a systematic review and meta-analysis of (subgroup analyses from) randomized controlled trials
AbstractBalancing stroke prevention and risk of bleeding in patients with atrial fibrillation (AF) is challenging. Direct oral anticoagulants (DOACs) are by now considered standard of care for treating patients with AF in international guidelines. Our objective was to assess the safety of long-term intake of DOACs in older adults with AF. We included RCTs in elderly ( ≥ 65 years) patients with AF. A systematic search in MEDLINE and EMBASE was performed on 19 April 2022. For determination of risk of bias, the RoB 2 tool was applied. We pooled outcomes using random-effects meta-analyses. The quality of evidence was as...
Source: AGE - June 1, 2023 Category: Geriatrics Source Type: research
Influence of atrial fibrillation subtypes on anticoagulant therapy in a high-risk older population: the FAI project
CONCLUSIONS: In a population-based survey, AF pattern was an independent predictor of OAC treatment. Paroxysmal AF is still perceived as carrying a lower risk of vascular events.PMID:35543807 | DOI:10.1007/s40520-022-02140-w
Source: Aging Clinical and Experimental Research - May 11, 2022 Category: Geriatrics Authors: Antonio Di Carlo Fabio Mori Domenico Consoli Leonardo Bellino Augusto Zaninelli Marzia Baldereschi Maria Grazia D'Alfonso Chiara Gradia Alessandro Cattarinussi Bruno Sgherzi Giovanni Pracucci Benedetta Piccardi Bianca Maria Polizzi Domenico Inzitari Natio Source Type: research
Direct Oral Anticoagulants and Non-valvular Atrial Fibrillation: Compliance with Dose Level Guidelines in Patients Aged 80 Years and Over
ConclusionsAmong patients with non-valvular atrial fibrillation aged 80 years and over, about 40% of DOAC prescriptions feature inappropriate dose levels. It might be possible to reduce inappropriate dosing by raising awareness among hospital-based and private-practice prescribers, providing prescription support tools for DOACs, and performing medication reconciliations and reviews at hospital and in private practice.
Source: Drugs and Aging - September 6, 2021 Category: Geriatrics Source Type: research
Relationship between multimorbidity and outcomes in atrial fibrillation
CONCLUSIONS: In a nationwide contemporary cohort of AF anticoagulated patients, multimorbidity was inversely associated with good anticoagulation control. A progressively higher risk for major bleeding, CV death and all-cause death was found across CCI quartiles.PMID:34303775 | DOI:10.1016/j.exger.2021.111482
Source: Experimental Gerontology - July 25, 2021 Category: Geriatrics Authors: Marco Proietti Mar ía Asunción Esteve-Pastor Jos é Miguel Rivera-Caravaca Vanessa Rold án Inmaculada Rold án Rabadán Javier Mu ñiz Ángel Cequier Vicente Bertomeu-Mart ínez Lina Badim ón Manuel Anguita Gregory Y H Lip Francisco Mar ín FANTASIIA Source Type: research
Some Comments for Better Understanding of the Study Entitled & ldquo;Reduced Vitamin D Levels are Associated with Stroke-Associated Pneumonia in Patients with Acute Ischemic Stroke & rdquo; Letter
Source: Clinical Interventions in Aging - February 5, 2020 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research
Reduced Vitamin D Levels are Associated with Stroke-Associated Pneumonia in Patients with Acute Ischemic Stroke
Source: Clinical Interventions in Aging - December 31, 2019 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research
Retracted: Effect of immobilization on vitamin D status and bone mass in chronically hospitalized disabled stroke patients
Following the appraisal of new information, the editorial board of Age and Ageing have retracted this paper from the scientific record. In February 2019, Age and Ageing published an expression of concern online regarding this paper, noting multiple issues with the data presented in the manuscript. Further information has now come to light in that, at the time of data collection for the reported work, neither the hospital nor the academic institution to which the lead author was affiliated, and where the study participants were recruited, had an institutional review board to provide ethical approval for the work reported. N...
Source: Age and Ageing - November 20, 2019 Category: Geriatrics Source Type: research
87 Evolution of Atrial Fibrillation
ConclusionThere has been a significant increase in primary prevention practices for AF and this is reflected in the number of stroke patients presenting with known AF on a NOAC, however more needs to be done as there are still patients who have AF that are not being anticoagulated in the community.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research
Association between vitamin D status and cognitive impairment in acute ischemic stroke patients: a prospective cohort study
Source: Clinical Interventions in Aging - December 10, 2018 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research
Introduction of Non-Vitamin K Antagonist Anticoagulants Strongly Increased the Rate of Anticoagulation in Hospitalized Geriatric Patients with Atrial Fibrillation
ConclusionThe introduction of non-vitamin K antagonist oral anticoagulants and an increased awareness of their benefits led to an increased use of anticoagulation from 52.8% (2011) to 87.7% (2015) in geriatric patients with atrial fibrillation and flutter at our institution.
Source: Drugs and Aging - August 1, 2018 Category: Geriatrics Source Type: research
Effectiveness and safety of oral anticoagulants in older patients with atrial fibrillation: a systematic review and meta-regression analysis
Conclusionswarfarin use was superior to warfarin non-use, aspirin and no antithrombotic therapy in reducing the risk of stroke/TE in older AF patients, but with a possible increase in major bleeding. NOACs were superior to warfarin for stroke/TE prevention, with reduced risk of major bleeding.
Source: Age and Ageing - September 8, 2017 Category: Geriatrics Source Type: research
