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Obesity paradox and stroke: a narrative review.
CONCLUSIONS: The existence of an obesity paradox in stroke is still controversial and further higher quality evidence is needed to clarify the relationship between obesity and stroke outcome. LEVEL OF EVIDENCE: Level V, narrative review. PMID: 32124408 [PubMed - as supplied by publisher]
Source: Eating and weight disorders : EWD - March 1, 2020 Category: Eating Disorders & Weight Management Authors: Forlivesi S, Cappellari M, Bonetti B Tags: Eat Weight Disord Source Type: research

A dose‐response meta‐analysis of the impact of body mass index on stroke and all‐cause mortality in stroke patients: a paradox within a paradox
Summary The obesity paradox is often attributed to fat acting as a buffer to protect individuals in fragile metabolic states. If this was the case, one would predict that the reverse epidemiology would be apparent across all causes of mortality including that of the particular disease state. We performed a dose‐response meta‐analysis to assess the impact of body mass index (BMI) on all‐cause and stroke‐specific mortality among stroke patients. Data from relevant studies were identified by systematically searching PubMed, OVID and Scopus databases and were analysed using a random‐effects dose‐response model. Eig...
Source: Obesity Reviews - March 1, 2015 Category: Eating Disorders and Weight Management Authors: M. Bagheri, J. R. Speakman, S. Shabbidar, F. Kazemi, K. Djafarian Tags: Review Source Type: research

“Case series: ischemic stroke associated with dehydration and arteriosclerosis in individuals with severe anorexia nervosa”
ConclusionsDevelopment of ischemic stroke in patients with AN might be overlooked. Watching out for neurological signs would help in early diagnosis of ischemic stroke in patients with AN during refeeding. Specific etiology could induce ischemic stroke in patients with AN even if they have no common risk factors of ischemia.
Source: Journal of Eating Disorders - March 20, 2021 Category: Eating Disorders & Weight Management Source Type: research

Evaluation of the Obesity Genes FTO and MC4R for Contribution to the Risk of Large Artery Atherosclerotic Stroke in a Chinese Population
Background: Obesity is a well-established risk factor for large artery atherosclerotic (LAA) stroke. The aim of the study was to explore whether obesity genes, such asMC4R and FTO, contribute to LAA stroke risk in the Chinese Han population.Methods: 322 LAA stroke patients and 473 controls were recruited. Gene polymorphism ofMC4R (rs17782313) andFTO (rs8050136 and rs9939609) were genotyped.Results: No differences were observed in genotype frequencies of variants ofFTO (rs8050136 and rs9939609) orMC4R (rs17782313) between LAA stroke patients and control subjects. However, rs17782313 of theMC4R gene was associated with LAA s...
Source: Obesity Facts - October 4, 2016 Category: Eating Disorders and Weight Management Source Type: research

Evaluation of the Obesity Genes < b > < i > FTO < /i > < /b > and < b > < i > MC4R < /i > < /b > for Contribution to the Risk of Large Artery Atherosclerotic Stroke in a Chinese Population
Background: Obesity is a well-established risk factor for large artery atherosclerotic (LAA) stroke. The aim of the study was to explore whether obesity genes, such asMC4R and FTO, contribute to LAA stroke risk in the Chinese Han population.Methods: 322 LAA stroke patients and 473 controls were recruited. Gene polymorphism ofMC4R (rs17782313) andFTO (rs8050136 and rs9939609) were genotyped.Results: No differences were observed in genotype frequencies of variants ofFTO (rs8050136 and rs9939609) orMC4R (rs17782313) between LAA stroke patients and control subjects. However, rs17782313 of theMC4R gene was associated with LAA s...
Source: Obesity Facts - November 8, 2016 Category: Eating Disorders and Weight Management Source Type: research

Is addictive-like eating an overlooked stroke risk factor? A study case.
CONCLUSION: Food addiction might be considered as an emerging stroke risk factor. We suggest it fosters the need to take into consideration addictive-like eating behaviors and associated mental disorders in the primary and secondary prevention of stroke. This may be particularly relevant for the prevention of stroke in women as they are more prone to comfort their emotions with food. LEVEL OF EVIDENCE: V, descriptive study. PMID: 33559834 [PubMed - as supplied by publisher]
Source: Eating and weight disorders : EWD - February 9, 2021 Category: Eating Disorders & Weight Management Authors: Rabat Y, Berthoz S, Sibon I Tags: Eat Weight Disord Source Type: research

Adiponectin and incident coronary heart disease and stroke. A systematic review and meta‐analysis of prospective studies
In conclusion, plasma adiponectin is not related to the risk for incident CHD or stroke.
Source: Obesity Reviews - March 18, 2013 Category: Eating Disorders and Weight Management Authors: D. A. Kanhai, M. E. Kranendonk, C. S. P. M. Uiterwaal, Y. Graaf, L. J. Kappelle, F. L. J. Visseren Tags: Etiology and Pathophysiology/Obesity Comorbidity Source Type: research

Estimating Effect of Obesity on Stroke Using G-Estimation: The ARIC study.
CONCLUSIONS: Both GOB and AOB affected the risk of stroke. The magnitude of the estimates was larger when modeled by G-estimation than when using standard models, suggesting that bias from mishandling of time-varying confounding was toward the null. PMID: 30677257 [PubMed - in process]
Source: Obesity - January 25, 2019 Category: Eating Disorders & Weight Management Authors: Shakiba M, Mansournia MA, Kaufman JS Tags: Obesity (Silver Spring) Source Type: research

Impact of metabolic disorders on the relation between overweight/obesity and incident myocardial infarction and ischaemic stroke in fertile women: a nationwide cohort study
ConclusionsThe risk of myocardial infarction and ischaemic stroke was more strongly associated with the presence of metabolic disorders than with overweight per se in fertile women. Targeting prevention of metabolic disorders might be beneficial to reduce cardiovascular disease in overweight/obese young women.
Source: Clinical Obesity - April 15, 2015 Category: Eating Disorders and Weight Management Authors: S. S. Andersen, C. Andersson, S. M. Berger, T. B. Jensen, C. T. Torp‐Pedersen, G. H. Gislason, L. Køber, M. D. Schmiegelow Tags: Original Article Source Type: research

Obesity paradox and stroke outcomes according to stroke subtype: a propensity score-matched analysis
International Journal of Obesity, Published online: 03 May 2023; doi:10.1038/s41366-023-01318-0Obesity paradox and stroke outcomes according to stroke subtype: a propensity score-matched analysis
Source: International Journal of Obesity - May 3, 2023 Category: Eating Disorders & Weight Management Authors: Sang-Hun Lee Jin-Man Jung Moon-Ho Park Source Type: research

A risk algorithm for assessing short-term mortality for obese black and white men and women: The reasons for geographic and racial differences in stroke (REGARDS).
Conclusions: We established and validated a risk algorithm to predict mortality among black and white obese subjects based on CHD risk factors, behavioral risk factors, and socioeconomic status. PMID: 24115735 [PubMed - as supplied by publisher]
Source: Obesity - September 30, 2013 Category: Eating Disorders and Weight Management Authors: Lakoski SG, Mallick H, McClure LA, Safford M, Kissela B, Howard G, Cushman M Tags: Obesity (Silver Spring) Source Type: research

Mediterranean Diet May Lower Stroke Risk, Study Finds
Title: Mediterranean Diet May Lower Stroke Risk, Study FindsCategory: Health NewsCreated: 2/12/2015 12:00:00 AMLast Editorial Review: 2/13/2015 12:00:00 AM
Source: MedicineNet Weight Management General - February 13, 2015 Category: Eating Disorders and Weight Management Source Type: news

Obesity and hyperglycemia lead to impaired post-ischemic recovery after permanent ischemia in mice.
CONCLUSIONS: These data suggest that impaired Wnt signaling and active apoptosis result in reduced post-stroke recovery in obese and hyperglycemic mice. PMID: 26694743 [PubMed - as supplied by publisher]
Source: Obesity - December 23, 2015 Category: Eating Disorders and Weight Management Authors: Tulsulkar J, Nada SE, Slotterbeck BD, McInerney MF, Shah ZA Tags: Obesity (Silver Spring) Source Type: research

Racial disparity in life expectancies and life years lost associated with multiple obesity-related chronic conditions.
CONCLUSIONS: Racial disparity exists in incident disease and mortality risks, LEs, and LYL associated with multiple OCCs. Efforts targeting subpopulations with large disparities are required to reduce disparities in the burden of multiple OCCs. PMID: 28329429 [PubMed - as supplied by publisher]
Source: Obesity - March 22, 2017 Category: Eating Disorders and Weight Management Authors: Chang SH, Yu YC, Carlsson NP, Liu X, Colditz GA Tags: Obesity (Silver Spring) Source Type: research

The cost‐effectiveness of primary care referral to a UK commercial weight loss programme
This study investigated whether such a programme was cost‐effective compared with usual care. A decision‐analytical Markov model was developed to estimate the lifetime costs and benefits of the referral programme compared with usual care and enable a cost‐utility analysis. The model cohort transited between body mass index classifications and type 2 diabetes, stroke and myocardial infarction (MI) with risk, cost and effect parameter values taken from published literature. The cost per incremental quality‐adjusted life year (QALY) was calculated. Extensive deterministic and scenario sensitivity analyses and probabil...
Source: Clinical Obesity - November 19, 2014 Category: Eating Disorders and Weight Management Authors: D. M. Meads, C. T. Hulme, P. Hall, A. J. Hill Tags: Original Article Source Type: research

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