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Total 345 results found since Jan 2013.

Diagnosing and managing sleep apnea in patients with chronic cerebrovascular disease: a randomized trial of a home-based strategy.
CONCLUSIONS: Patients with cerebrovascular disease and hypertension have a high prevalence of OSA. The use of portable polysomnography, and auto-titrating CPAP in the patients' homes, improved both the diagnosis and the treatment for sleep apnea compared with usual care but did not lower blood pressure. PMID: 28386781 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - April 6, 2017 Category: Sleep Medicine Authors: Bravata DM, McClain V, Austin C, Ferguson J, Burrus N, Miech EJ, Matthias MS, Chumbler N, Ofner S, Foresman B, Sico J, Vaz Fragoso CA, Williams LS, Agarwal R, Concato J, Klar Yaggi H Tags: Sleep Breath Source Type: research

A potential impact of Helicobacter pylori infection on both obstructive sleep apnea and atrial fibrillation-related stroke
Poli et al [1] concluded that atrial fibrillation (AF) was a major source of stroke in patients with high prevalence of obstructive sleep apnea (OSA).
Source: Sleep Medicine - March 30, 2017 Category: Sleep Medicine Authors: Constantinos Kountouras, Stergios A. Polyzos, Christos Stergiopoulos, Panagiotis Katsinelos, Dimitri Tzivras, Christos Zavos, Elisabeth Vardaka, Emmanuel Gavalas, Efi Vlachogianni, Ioanna Tzivras, Efimia Vlachaki, Georgia Deretzi, Evaggelia Giartza-Taxido Tags: Letter to the Editor Source Type: research

Study of association of severity of sleep disordered breathing and functional outcome in stroke patients
Sleep disordered breathing (SDB) is a prevalent yet underrecognized condition that may have major adverse consequences for those affected by it. We performed a prospective observational study to seek a correlation between the severity of SDB and the severity of stroke and its functional outcome.
Source: Sleep Medicine - March 17, 2017 Category: Sleep Medicine Authors: Rohit Kumar, J.C. Suri, Rajesh Manocha Tags: Original Article Source Type: research

Circulating Anti-Coatomer Protein Complex Subunit Epsilon (COPE) Autoantibodies as a Potential Biomarker for Cardiovascular and Cerebrovascular Events in Patients with Obstructive Sleep Apnea
Conclusions:An elevated COPE-Ab level may be a potential predictor of the risks of cardiovascular and cerebrovascular events in patients with OSA. Therefore, patients with higher COPE-Ab levels may require more careful and intensive treatment.Commentary:A commentary on this article appears in this issue on page 361.Citation:Matsumura T, Terada J, Kinoshita T, Sakurai Y, Yahaba M, Ema R, Amata A, Sakao S, Nagashima K, Tatsumi K, Hiwasa T. Circulating anti-coatomer protein complex subunit epsilon (COPE) autoantibodies as a potential biomarker for cardiovascular and cerebrovascular events in patients with obstructive sleep ap...
Source: Journal of Clinical Sleep Medicine : JCSM - March 15, 2017 Category: Sleep Medicine Source Type: research

Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline
Introduction:This guideline establishes clinical practice recommendations for the diagnosis of obstructive sleep apnea (OSA) in adults and is intended for use in conjunction with other American Academy of Sleep Medicine (AASM) guidelines on the evaluation and treatment of sleep-disordered breathing in adults.Methods:The AASM commissioned a task force of experts in sleep medicine. A systematic review was conducted to identify studies, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) process was used to assess the evidence. The task force developed recommendations and assigned strengths base...
Source: Journal of Clinical Sleep Medicine : JCSM - March 15, 2017 Category: Sleep Medicine Source Type: research

Rehabilitation of Cardiovascular Disorders and Sleep Apnea
Obstructive sleep apnea (OSA) is present in more than 50% of patients referred to cardiac rehabilitation units. However, it has been under-recognized in patients after stroke and heart failure. Those with concurrent OSA have worse clinical course. Early treatment of coexisting OSA with continuous positive airway pressure (CPAP) results in improved rehabilitation outcomes and quality of life. Possible mechanisms by which CPAP may improve recovery include decreased blood pressure fluctuations associated with apneas, and improved left ventricular function, cerebral blood flow, and oxygenation. Early screening and treatment of...
Source: Sleep Medicine Clinics - March 8, 2017 Category: Sleep Medicine Authors: Behrouz Jafari Source Type: research

The increased risk of stroke in early insomnia following traumatic brain injury: a population-based cohort study
This study aims to investigate whether insomnia is a potential risk factor for stroke after TBI, especially early insomnia.
Source: Sleep Medicine - March 6, 2017 Category: Sleep Medicine Authors: Kam-Hou Ao, Chung-Han Ho, Che-Chuan Wang, Jhi-Joung Wang, Chung-Ching Chio, Jinn-Rung Kuo Tags: Original Article Source Type: research

Is a “gut full” of bad bugs driving metabolic disease in shift workers?
Shift workers make up a significant proportion of the total workforce in industrialised countries, with about one in five employees working during night time hours.1 There is strong epidemiological evidence that these workers are at increased risk for developing obesity, type II diabetes, coronary heart disease, stroke and cancer.2 Furthermore, obesity can contribute to worsening of other conditions that are commonly suffered by shift workers such as sleep apnoea. The mechanisms that promote obesity and metabolic disease amongst shift workers are thought to arise from an imposed chronic disruption and misalignment between ...
Source: Sleep Medicine Reviews - February 19, 2017 Category: Sleep Medicine Authors: Craig L. Phillips, Maria Comas Tags: Editorial Source Type: research

Restless legs syndrome and periodic limb movements after lacunar stroke
Although anatomical and physiological considerations suggest a possible causality between subcortical brain areas lesions and emergence of sleep-related movement disorders, few data are available regarding the association between restless legs syndrome/periodic limb movements (RLS/PLM) and lacunar stroke [1]. The aim of this study was to evaluate the prevalence and the lesion topography of new-onset RLS/PLM in patients with lacunar stroke. In addition, we tried to add some details about the characterization of sleep-related movement disorders in relation to the site and side of the ischemic lesion.
Source: Sleep Medicine - February 11, 2017 Category: Sleep Medicine Authors: L. Buratti, C. Petrelli, G. Viticchi, C. Petrelli, G. Viticchi, L. Falsetti, M. Silvestrini Tags: Letter to the Editor Source Type: research

Is obstructive sleep apnea associated with the presence of intracranial cerebral atherosclerosis?
CONCLUSIONS: Our findings suggest that moderate to severe OSA is associated with the presence of ICAS in patients with suspected OSA. PMID: 28168435 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - February 6, 2017 Category: Sleep Medicine Authors: Song TJ, Park JH, Choi KH, Kim JH, Choi Y, Chang Y, Kim HJ, Moon J, Kim YJ, Lee HW Tags: Sleep Breath Source Type: research

Obstructive sleep apnea exaggerates cognitive dysfunction in stroke patients
Obstructive sleep apnea (OSA) is very common in stroke survivors. It potentially worsens the cognitive dysfunction and inhibits their functional recovery. However, whether OSA independently damages the cognitive function in stroke patients is unclear. A simple method for evaluating OSA-induced cognitive impairment is also missing.
Source: Sleep Medicine - February 2, 2017 Category: Sleep Medicine Authors: Yan Zhang, Wanhua Wang, Sijie Cai, Qi Sheng, Shenggui Pan, Fang Shen, Qing Tang, Yang Liu Tags: Original Article Source Type: research

Stratification of cardiovascular risk in patients with atrial fibrillation and obstructive sleep apnea-validity of the 2MACE score.
CONCLUSION: OSA prevalence is increased in AF patients and is associated with an increase 2MACE score-an indicator of major cardiovascular events. There is a linear relationship between severity of OSA and increasing 2MACE scores, indicating increasing cardiovascular risk related to OSA severity. PMID: 28155102 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - February 1, 2017 Category: Sleep Medicine Authors: Platek AE, Szymanski FM, Filipiak KJ, Dudzik-Plocica A, Krzowski B, Karpinski G Tags: Sleep Breath Source Type: research

Cerebral Microbleeds on MRI in Patients with Obstructive Sleep Apnea
Conclusions:Moderate-to-severe OSA can be one of the independent predictors of CMBs which are considered a surrogate marker of overt stroke.Citation:Koo DL, Kim JY, Lim JS, Kwon HM, Nam H. Cerebral microbleeds on MRI in patients with obstructive sleep apnea.J Clin Sleep Med. 2017;13(1):65–72.
Source: Journal of Clinical Sleep Medicine : JCSM - January 14, 2017 Category: Sleep Medicine Source Type: research

Spontaneous Improvement in Both Obstructive Sleep Apnea and Cognitive Impairment after Stroke
Knowledge available about the relationship between obstructive sleep apnea (OSA) and cognitive impairment after stroke is limited. The evolution of OSA and cognitive performance after stroke is not sufficiently described.
Source: Sleep Medicine - January 13, 2017 Category: Sleep Medicine Authors: J. Slonkova, M. Bar, P. Nilius, D. Berankova, D. Salounova, K. Sonka Tags: Original Article Source Type: research

The role of the Nox4-derived ROS-mediated RhoA/Rho kinase pathway in rat hypertension induced by chronic intermittent hypoxia.
CONCLUSION: Hypertension can be induced by CIH in SD rats. The CIH-induced elevation of BP is at least partially mediated via the Nox4-induced ROS/RhoA/ROCK pathway. PMID: 28078487 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - January 10, 2017 Category: Sleep Medicine Authors: Lu W, Kang J, Hu K, Tang S, Zhou X, Xu L, Li Y, Yu S Tags: Sleep Breath Source Type: research