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Specialty: Dermatology
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Total 354 results found since Jan 2013.
096 Demographic and serologic features differentiate bullous pemphigoid with and without preceding neurologic disease
This study aimed to identify features that may differentiate BP patients with and without neurologic disease. 105 patients with BP were enrolled in this study: 75 control BP patients with no neurologic disease (CON), 10 patients with BP and a prior diagnosis of Parkinson ’s disease (BP+PD), 11 BP with dementia patients (BP+DEM), and 9 BP with stroke (BP+STR).
Source: Journal of Investigative Dermatology - April 27, 2018 Category: Dermatology Authors: A. Miller, K. Messingham, N. Narayanan, S. Connell, J. Fairley Tags: Adaptive and Auto-Immunity Source Type: research
Prevalence of smoking, alcohol consumption and metabolic syndrome in patients with psoriasis
Conclusions: Our results indicate that MBS is a risk factor for psoriasis patients with advanced age. The relationship between disease severity and obesity, diabetes, and smoking in psoriasis patients indicates that the patients should be informed about the potential metabolic risks and receive therapies for behavioral changes besides anti-psoriatic treatment in order to minimize these risks.
Source: Anais Brasileiros de Dermatologia - May 3, 2018 Category: Dermatology Source Type: research
The bacteria stroke: Leclercia adecarboxylata folliculitis in a healthy swimmer —an emerging aquatic pathogen?
A 12-year-old healthy boy presented with a 2-month painful acneiform eruption. On exam erythematous follicular papules and pustules were scattered over bilateral shoulders and back. These surfaces were moderately tender to light palpation; the patient even complained that clothing in contact with his skin elicited pain. Doxycycline 75 mg po qd × 10 days was prescribed to cover common Staphylococcus aureus folliculitis. Due to the atypical presentation of significant pain, a bacterial culture was collected.
Source: Journal of the American Academy of Dermatology - August 2, 2018 Category: Dermatology Source Type: research
Sturge Weber syndrome: A rare clinical presentation with bilateral port wine stain and leptomenigeal angiomatosis
Introduction: Sturge-Weber syndrome (SWS) is a neurocutaneous syndrome that has a heterogeneous spectrum of manifestations, characterized by facial port-wine stain (PWS) within the trigeminal nerve distribution, ipsilateral leptomeningeal angiomatosis, glaucoma, seizures, stroke-like episodes, hemiparesis, and mental retardation. The diagnosis is based on clinical presentation and cranial imaging features. Treatment is a challenge and multidisciplinary approach is required to control ophthalmic, neurologic and dermatologic manifestations.
Source: Journal of the American Academy of Dermatology - August 2, 2018 Category: Dermatology Source Type: research
Demographics and Autoantibody Profiles of Pemphigoid Patients with Underlying Neurologic Diseases
Bullous pemphigoid (BP) is an autoantibody-mediated blistering disease that is often associated with neurologic disease. BP antibodies target two epidermal adhesion molecules, known as BP180 and BP230. Homologues to these proteins are found in the brain, and it is hypothesized that neurologic disease leads to the production of autoantibodies that can cross react with their cutaneous forms. To better understand the link between BP and neurologic disease, we evaluated primary demographic features (age, sex, race, ethnicity and elapsed time between onset of skin symptoms and BP diagnosis), severity of BP, and IgG and IgE auto...
Source: Journal of Investigative Dermatology - March 11, 2019 Category: Dermatology Authors: Kelly N. Messingham, Adam D. Miller, Nandakumar S. Narayanan, Samuel J. Connell, Janet A. Fairley Tags: Original Article Source Type: research
817 Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency
Excessive alcohol consumption leads to alcohol use disorder. Alcohol is metabolized to acetaldehyde, which is then oxidized to acetic acid by aldehyde dehydrogenases (ALDH), a class of enzymes that facilitate the conversion of aldehydes to their corresponding acids. Among ALDHs, mitochondrial ALDH2 is the primary enzyme involved in the metabolism of acetaldehyde. In addition to its well-known role in ethanol metabolism, recent studies have suggested that ALDH2 dysfunction is associated with a variety of human diseases including cardiovascular diseases, diabetes, neurodegenerative diseases, stroke, cancer, anemia, pain, osteoporosis and aging.
Source: Journal of Investigative Dermatology - April 19, 2019 Category: Dermatology Authors: T. Yamauchi, A. Matsumoto, S. Ito, K. Wakamatsu, T. Suzuki, M. Fujita Tags: Pigmentation and Melanoma Source Type: research
Preventing and Treating Injuries Caused by Water Sports and Activities
Boating, swimming, fishing and other water sports are popular summertime pursuits but can sometimes have the potential for danger. Here are some tips for dealing with injuries from water activities.
Swimming problems. According to the American Orthopaedic Society for Sports Medicine, most swimming injuries involve the shoulders, back, hips or knees, depending on the individual's stroke. Treatment recommendations from the AOSSM include cutting back on repetitive strokes contributing to overuse, core-strengthening and cross-training exercises, rest periods, alternative training techniques (instead of train...
Source: Advanced Tissue - June 6, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound Infection Source Type: news
Treating and managing diabetic neuropathic foot ulcers
A study by the Centers for Disease Control and Prevention reports that diabetes rates are at a steady growth, with more than 100 million people in the country living with diabetes or prediabetes as of 2017. This condition has a major impact on overall health and wellness and can cause serious complications involving vision loss, heart disease, stroke, and even toe, foot or leg amputation due to ulcers.
Defining diabetic foot ulcers
According to the American Podiatric Medical Association, a diabetic foot ulcer is an open wound or sore that occurs in those who have diabetes. Diabetic patients are more likely to develo...
Source: Advanced Tissue - July 1, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care diabetic foot ulcers Source Type: news
9824 —Prevention of taxane-induced alopecia and nail toxicity
Introduction: Hidradenitis suppurativa (HS) and psoriasis have been linked to cardiovascular disease. There is currently a deficiency in the literature regarding the prevalence of clinically important cardiovascular diseases that arise in patients with HS in a United States population. We sought to determine the odds of stroke, coronary artery disease (CAD), heart failure (HF), and peripheral artery disease (PAD) in patients with HS compared with patients with psoriasis and controls.
Source: Journal of the American Academy of Dermatology - August 21, 2019 Category: Dermatology Source Type: research
Evaluation of plasma levels of tissue factor and tissue factor pathway inhibitor in patients with psoriasis.
Conclusions: It appears that further studies are necessary to explain this problem, perhaps to include an evaluation of TF levels in psoriatic skin.
PMID: 31616219 [PubMed]
Source: Advances in Dermatology and Allergology - October 17, 2019 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Neuroimaging provides relevant clinical information in patients with burn injuries
ConclusionNeuroimaging is used appropriately in patients admitted with burns and provides valuable applicable clinical information when indicated.
Source: Burns - November 29, 2019 Category: Dermatology Source Type: research
The risk of myocardial infarction, stroke and revascularization among patients with psoriasis treated with apremilast compared to biologics and DMARDs: a cohort study in the United States MarketScan database
Source: Journal of the American Academy of Dermatology - March 24, 2020 Category: Dermatology Authors: Rebecca Persson, Katrina Wilcox Hagberg, Ellen (Yiran) Qian, Catherine Vasilakis-Scaramozza, Susan Jick Source Type: research
Atypical purpuric oedema of the nose during granulomatosis with polyangiitis.
We report the case of a 47-year-old woman presenting purpuric oedematous plaque with bullous detachment of the nose and hospitalised for the assessment of two suspicious neoplastic lung lesions discovered as a result of a recent stroke and repeated seromucosal otitis. Granulomatosis with polyangeitis was suspected because of multiple systemic lesions. The histopathology of skin lesions and laboratory investigation results were consistent with this diagnosis. A favourable outcome was achieved with corticosteroids and rituximab.
DISCUSSION: The diagnosis of GPA is based on criteria established by the American College of...
Source: Annales de Dermatologie et de Cenereologie - April 14, 2020 Category: Dermatology Authors: Colas M, Bentz MH, Raffoul J, Devalland C, Dupond AS Tags: Ann Dermatol Venereol Source Type: research
In memoriam: Haines Ely, MD, FAAD
Aside from the news about the canceling of the American Academy of Dermatology Annual Meeting in Denver, there is horrible news that is difficult with every key stroke as I write today …Dr Haines Ely, long-standing pinnacle member of Noah Worcester, Pacific Dermatologic Association, RxDerm, and the American Academy of Dermatology, has passed away after a long battle with prostate cancer. He is survived by his wife, Jenny, and adult daughters, Meredith Bordoni (Michael), Rebecca Ely, and Tess Ely.
Source: Journal of the American Academy of Dermatology - March 12, 2020 Category: Dermatology Authors: Neal Bhatia Tags: In memoriam Source Type: research
Paraoxonase-1 and other factors related to oxidative stress in psoriasis.
Conclusions: Psoriasis promotes arteriosclerosis development by decreasing the levels of antiatherogenic and increasing the levels of proatherogenic agents. Adverse changes in psoriatic patients involve activity of paraoxonase-1, levels of α-tocopherol, uric acid, homocysteine as compared to healthy individuals selected by their age, BMI and abdominal circumference value.
PMID: 32467691 [PubMed]
Source: Advances in Dermatology and Allergology - May 31, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
