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Right-sided weakness in a Rwandan patient with untreated Tetralogy of Fallot
DiscussionIn countries where surgical repair of TOF is not available, early recognition and medical management are key in temporizing the development of devastating sequelae. Describing the prevalence of CHD in Rwanda is urgent, requiring further research by which effective prevention and treatment strategies can be developed.
Source: International Journal of Emergency Medicine - March 14, 2023 Category: Emergency Medicine Source Type: research

Aortic root management in acute type A aortic dissection: A nationwide analysis
ConclusionIn selected patients, AVr is being performed safely in the setting of ATAAD with mortality and composite outcomes comparable to AVR.
Source: Journal of Cardiac Surgery - July 26, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Edward D. Percy, Morgan T. Harloff, Paige C. Newell, Muntasir Chowdhury, Supreet Singh, Sameer A. Hirji, Farhang Yazdchi, Thais F. Vinholo, Mariam Kerolos, Tsuyoshi Kaneko, Ashraf A. Sabe Tags: ORIGINAL ARTICLE Source Type: research

Temporal Trends and Outcomes of Elective Thoracic Aortic Repair and Acute Aortic Syndromes in Bicuspid Aortic Valves: Insights from a National Database
ConclusionData from a national database showed no change in the number of hospitalizations for BAV-related aortopathy, with relatively lower incidence of AAS. Compared with TAV, elective aortic repair for BAV is associated with lower mortality, while BAV-related AAS is associated with higher in-hospital complications.
Source: Cardiology and Therapy - August 24, 2021 Category: Cardiology Source Type: research

COVID-19 Exposed the Faults in America ’s Elder Care System. This Is Our Best Shot to Fix Them
For the American public, one of the first signs of the COVID-19 pandemic to come was a tragedy at a nursing home near Seattle. On Feb. 29, 2020, officials from the U.S. Centers for Disease Control and Prevention (CDC) and Washington State announced the U.S. had its first outbreak of the novel coronavirus. Three people in the area had tested positive the day before; two of them were associated with Life Care Center of Kirkland, and officials expected more to follow soon. When asked what steps the nursing home could take to control the spread, Dr. Jeff Duchin, health officer for Seattle and King County, said he was working w...
Source: TIME: Health - June 15, 2021 Category: Consumer Health News Authors: Abigail Abrams Tags: Uncategorized Aging COVID-19 feature franchise Magazine TIME for Health Source Type: news

Effects of Normothermic Machine Perfusion Conditions on Mesenchymal Stromal Cells
In this study the effect of NMP perfusion fluid on survival, metabolism and function of thawed cryopreserved human (h)MSC and porcine (p)MSC in suspension conditions was studied. Suspension conditions reduced the viability of pMSC by 40% in both perfusion fluid and culture medium. Viability of hMSC was reduced by suspension conditions by 15% in perfusion fluid, whilst no differences were found in survival in culture medium. Under adherent conditions, survival of the cells was not affected by perfusion fluid. The perfusion fluid did not affect survival of fresh MSC in suspension compared to the control culture medium. The f...
Source: Frontiers in Immunology - April 9, 2019 Category: Allergy & Immunology Source Type: research

Teaching NeuroImages: Abnormal cervical and cerebral vasculature in 22q11 deletion syndrome
A 12-day-old girl with a postnatal microarray diagnosis of 22q11.2 deletion syndrome was transferred for surgical repair of truncus arteriosus. Neurologic examination at the time of transfer was unremarkable. Brain MRI on day of life 9 demonstrated an absent left internal carotid flow void. Magnetic resonance angiography of the head (figure, A) and neck (figure, B) was subsequently obtained prior to cardiac repair. Patients with 22q11 deletion syndromes may have abnormal cervical vessel development.1 Children with congenital heart disease have an elevated stroke risk, particularly for periprocedural stroke.2 Understanding ...
Source: Neurology - July 3, 2017 Category: Neurology Authors: Mithal, D. S., Kurz, J. E. Tags: All Cerebrovascular disease/Stroke, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, All Genetics RESIDENT AND FELLOW SECTION Source Type: research

Preservation of left ventricular function after degenerative mitral valve repair: Refocusing on timing, techniques, and teaching
Changes in left ventricular (LV) size and function are expected after correction of severe chronic degenerative mitral regurgitation. Although it was previously thought that a postoperative decrease in ejection fraction (EF) was related to inadequate myocardial protection, it is now recognized that elimination of regurgitant volume after mitral valve repair is often associated with an increase in LV end-systolic volume, producing a decline in EF while maintaining normal or increased LV stroke volume.
Source: The Journal of Thoracic and Cardiovascular Surgery - July 18, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Rakesh M. Suri, Maurice Enriquez-Sarano, Hartzell V. Schaff Tags: Editorial: Acquired mitral valve Source Type: research