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Reduction of lung hyperinflation improves cardiac preload, contractility, and output in emphysema
Conclusions: Reduction of hyperinflation using BLVR with endobronchial valves significantly improved cardiac preload, myocardial contractility, and cardiac output, without changes in pulmonary artery pressures.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: van der Molen, M., Hartman, J., Vanfleteren, L., Kerstjens, H., Van Melle, J., Willems, T., Slebos, D. Tags: 01.02 - Rehabilitation and chronic care Source Type: research

Reduction of Lung Hyperinflation Improves Cardiac Preload, Contractility, and Output in Emphysema: A Prospective Cardiac Magnetic Resonance Study in Patients Who Received Endobronchial Valves
CONCLUSIONS: We found that reduction of hyperinflation using BLVR with endobronchial valves significantly improved cardiac preload, myocardial contractility, and cardiac output, without changes in pulmonary artery pressures. Clinical trial registered with ClinicalTrials.gov (NCT03474471).PMID:35584341 | DOI:10.1164/rccm.202201-0214OC
Source: Am J Respir Crit Car... - May 18, 2022 Category: Intensive Care Authors: Marieke C van der Molen Jorine E Hartman Lowie E G W Vanfleteren Huib A M Kerstjens Joost P van Melle Tineke P Willems Dirk-Jan Slebos Source Type: research

Risk factors of diffuse alveolar hemorrhage after acute ischemic stroke treated with tissue-type plasminogen activator. The effectiveness of activated recombinant factor VII treatment.
Conclusion: The inclusion/exclusion criteria of tPA were based on the AHA/ASA Guidelines for the early management of patients with AIS.These patients had no evidence of infections, bronchoscopy, autoimmune diseases, HIV, and transplantations. Our study suggests that systemic administration of rFVIIa for DAH is effective. Emphysema may be a risk factor for the development of DAH following tPA. When we use tPA for emphysema patients, we must be careful about DAH enough. PMID: 32547816 [PubMed]
Source: Surgical Neurology International - June 19, 2020 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Cardio-Pulmonary Changes After Bronchoscopic Lung Volume Reduction with Endobronchial One-Way Valves
ConclusionBronchoscopic valve treatment seemed to have positive effects on cardio-pulmonary hemodynamics, and these changes were correlated with reductions of lobar volume.
Source: Lung - April 6, 2020 Category: Respiratory Medicine Source Type: research

Thermal Vapor Ablation for Lung Lesions in a Porcine Model
Conclusions: Vapor ablation is a potentially safe and efficient means of ablating a targeted region of the lung. We hypothesize that vapor may be useful in treating lesions of the lung in humans.Respiration
Source: Respiration - July 8, 2015 Category: Respiratory Medicine Source Type: research