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Long-term effectiveness, outcomes and complications of bariatric surgery
World J Clin Cases. 2023 Jul 6;11(19):4504-4512. doi: 10.12998/wjcc.v11.i19.4504.ABSTRACTDietary imbalance and overeating can lead to an increasingly widespread disease - obesity. Aesthetic considerations aside, obesity is defined as an excess of adipose tissue that can lead to serious health problems and can predispose to a number of pathological changes and clinical diseases, including diabetes; hypertension; atherosclerosis; coronary artery disease and stroke; obstructive sleep apnea; depression; weight-related arthropathies and endometrial and breast cancer. A body weight 20% above ideal for age, gender and height is a...
Source: Atherosclerosis - July 20, 2023 Category: Cardiology Authors: Milena Gulinac Dimitrina Georgieva Miteva Monika Peshevska-Sekulovska Ivan P Novakov Svetozar Antovic Milena Peruhova Violeta Snegarova Plamena Kabakchieva Yavor Assyov Georgi Vasilev Metodija Sekulovski Snezhina Lazova Latchezar Tomov Tsvetelina Velikova Source Type: research

Is There a Role for Vitamin K Antagonist in the Management of Atrial Fibrillation in 2023?
AbstractPurpose of ReviewTo address the following question: Are vitamin K antagonists (VKA) obsolete as stroke prevention therapy for patients with atrial fibrillation (AF) and thromboembolic risk factors?Recent FindingsA patient-level meta-analysis of the pivotal phase III randomized trials confirmed the favorable treatment effect of direct oral anticoagulants (DOAC) over VKA in multiple key patient subgroups. Among patients with AF and rheumatic heart disease (85% of whom had mitral stenosis), a randomized trial showed that rivaroxaban was not superior to VKA for stroke prevention. Caution should be exercised when prescr...
Source: Current Cardiology Reports - March 30, 2023 Category: Cardiology Source Type: research

Association of Bariatric Surgery With Cardiovascular Outcomes in Adults With Severe Obesity and Nonalcoholic Fatty Liver Disease
CONCLUSIONS AND RELEVANCE: Results of this study suggest that, compared with nonsurgical care, bariatric surgery was associated with significant reduction in CVD risk in individuals with severe obesity and NAFLD.PMID:36205997 | DOI:10.1001/jamanetworkopen.2022.35003
Source: Atherosclerosis - October 7, 2022 Category: Cardiology Authors: Mohamed I Elsaid You Li John F P Bridges Guy Brock Carlos D Minacapelli Vinod K Rustgi Source Type: research

Bariatric Surgery Cuts Cardiovascular Events, Even in Seniors Bariatric Surgery Cuts Cardiovascular Events, Even in Seniors
In individuals with obesity, even those aged 65-75 years of age, bariatric surgery can reduce long-term cardiovascular events, such as heart failure, stroke, and myocardial infarction.Medscape Medical News
Source: Medscape Cardiology Headlines - April 15, 2022 Category: Cardiology Tags: Cardiology News Source Type: news

Bariatric Surgery Tied to 22% Lower 5-Year Stroke Risk Bariatric Surgery Tied to 22% Lower 5-Year Stroke Risk
Patients with obesity who underwent bariatric surgery had 46% lower odds of stroke 1 year later, similar odds of stroke 3 years later, and 22% lower odds of stroke 5 years later.Medscape Medical News
Source: Medscape Cardiology Headlines - June 21, 2021 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Effect of Bariatric Surgery on Cardiovascular Function and Heart Failure Outcomes
In this article, we explore the influence of obesity on cardiovascular health and the role of bariatric surgery in reducing cardiovascular comorbidities, preventing the onset of heart failure and improving mortality and quality of life in those with cardiac dysfunction. We highlight the mechanisms by which obesity leads to cardiovascular remodeling, diastolic dysfunction, and eventual heart failure. These mechanisms include systemic inflammation, local lipotoxicity by way of ectopic fat deposition, and hemodynamic alterations that have significant effects on cardiac structure and function. Bariatric surgery has been shown ...
Source: Cardiology in Review - June 11, 2021 Category: Cardiology Tags: Review Articles Source Type: research

Bariatric Surgery and the Risk of New-Onset Atrial Fibrillation in Swedish  Obese Subjects
BackgroundObesity is a risk factor for atrial fibrillation, which in turn is associated with stroke, heart failure, and increased all-cause mortality.ObjectivesThe authors investigated whether weight loss through bariatric surgery may reduce the risk of new-onset atrial fibrillation.MethodsSOS (Swedish Obese Subjects) is a prospective matched cohort study conducted at 25 surgical departments and 480 primary healthcare centers in Sweden. The cohort was recruited between 1987 and 2001. Among 4,021 obese  individuals with sinus rhythm and no history of atrial fibrillation, 2,000 underwent bariatric surgery (surgery group), a...
Source: Journal of the American College of Cardiology - December 5, 2016 Category: Cardiology Source Type: research

All-Cause and Cause-Specific Mortality Associated with Bariatric Surgery: A Review
Abstract The question of whether or not nonsurgical intentional or voluntary weight loss results in reduced mortality has been equivocal, with long-term mortality following weight loss being reported as increased, decreased, and not changed. In part, inconsistent results have been attributed to the uncertainty of whether the intentionality of weight loss is accurately reported in large population studies and also that achieving significant and sustained voluntary weight loss in large intervention trials is extremely difficult. Bariatric surgery has generally been free of these conflicts. Patients voluntarily unde...
Source: Current Atherosclerosis Reports - October 26, 2015 Category: Cardiology Source Type: research

Bariatric Surgery: "Roux"-minating on Endothelial Cell and HDL Function.
Abstract Obesity, defined as a body mass index ≥ 30 kg/m2, is pandemic. Though prevalence in the United States has plateaued at ~31% of adults (78 million), worldwide obesity rates continue to rise(1). Perhaps more concerning is the high level of childhood obesity: 16.9% in US and ~13% (and rising) in developing countries(2). Why the alarm? Longitudinal studies of overweight or obese individuals have identified a 20 fold increase in risk for developing diabetes mellitus type 2 (T2D) and 1.5 fold increase risk for cardiovascular disease (CVD), including myocardial infarction, stroke and heart failure(3, 4). As ob...
Source: Circulation - February 11, 2015 Category: Cardiology Authors: Brown JD Tags: Circulation Source Type: research

Bariatric surgery and its impact on cardiovascular disease and mortality: A systematic review and meta-analysis
Conclusions: Data from observational studies indicates that patients undergoing bariatric surgery have a reduced risk of myocardial infarction, stroke, cardiovascular events and mortality compared to non-surgical controls. Future randomized studies should investigate whether these observations are reproduced in a clinical trials setting.
Source: International Journal of Cardiology - March 13, 2014 Category: Cardiology Authors: Chun Shing Kwok, Ashish Pradhan, Muhammad A. Khan, Simon G. Anderson, Bernard D. Keavney, Phyo Kyaw Myint, Mamas A. Mamas, Yoon K. Loke Source Type: research

Abstract 203: Outcomes Comparison of Low Risk Medical and Surgical Patients Treated with Unfractionated Heparin vs. Enoxaparin Poster Session II
Conclusions: In low-risk medical and general surgical patients, UFH was as effective as enoxaparin in the prevention of thromboembolic events, with no difference in the incidence of HIT. When compared to UFH, enoxaparin was associated with lower MI and mortality rates, and shorter LOS and ICU LOS, at the expense of higher rates of stroke and TIA. Enoxaparin was associated with lower total inpatient costs than UFH.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Corbelli, J., Zammit, K., Griffiths, B., Ma, C., Tung, Y., Graves, C., Genena, D., Boyd, D., Meyer, F., Arbogast, P., Bourji, M. Tags: Poster Session II Source Type: research