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Condition: Heart Failure
Procedure: Lung Transplant

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Total 76 results found since Jan 2013.

Detection of inflow obstruction in left ventricular assist devices by accelerometer: A porcine model study
Left ventricular assist devices (LVAD) provide circulatory blood pump support for severe heart failure patients. Pump inflow obstructions may lead to stroke and pump malfunction. We aimed to verify in vivo that gradual inflow obstructions, representing prepump thrombosis, are detectable by a pump-attached accelerometer, where the routine use of pump power (PLVAD) is deficient.
Source: The Journal of Heart and Lung Transplantation - April 4, 2023 Category: Transplant Surgery Authors: Didrik Lilja, Itai Schalit, Andreas Espinoza, Arnt Eltvedt Fiane, Gry Dahle, Helen Littorin-Sandbu, Fred-Johan Pettersen, Kristoffer Engh Russell, Amrit Paul Singh Thiara, Ole Jakob Elle, Per Steinar Halvorsen Tags: Original Pre-Clinical Science Source Type: research

Impact of Perioperative Sarcopenia and Dysphagia on LVAD Related Complications
Sarcopenia, as defined by decline in muscle quantity/quality, is prevalent in heart failure and associated with high morbidity and mortality. Sarcopenic dysphagia is caused by sarcopenia in the whole body and swallowing-related muscles. We investigated the impact of perioperative sarcopenia and dysphagia on postoperative pneumonia (PNA), stroke, gastrointestinal bleeding (GIB) and 30-d readmission after LVAD.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: M. Nishikawa, M.R. Carey, A. Ladanyi, G.M. Mondellini, A. Pinsino, K. Antler, E. Goldberg, J. Hastie, K. Clerkin, G.T. Sayer, N. Uriel, K. Takeda, P.C. Colombo, M. Yuzefpolskaya Tags: (765) Source Type: research

Stroke and Survival Outcomes in Left Ventricular Device Patients
Left ventricular assist devices (LVADs) are artificial pumps used for hemodynamic support in patients with end stage heart failure. They can function effectively as a bridge to transplant as well as extend and improve the quality of life of patients. However, these patients are still at a higher risk of stroke, death, and other complications than the average population.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: N. Berg, C. Shah, M. Guglin, H. Ferguson Tags: (759) Source Type: research

Right heart failure after left ventricular assist device implantation – from prediction to action
In this issue of the Journal, Read and colleagues1 report the use of peak stroke volume index (SVI) during pre-procedure vasodilatory testing as a predictor of early right heart failure (RHF) after left ventricular assist device (LVAD) implantation. They retrospectively examine 70 patients from three institutions who underwent pre-implant nitroprusside vasodilator testing. Indications for pre-operative vasodilator testing were elevated pulmonary vascular resistance, pulmonary arterial wedge pressure, or systolic pulmonary artery pressure.
Source: The Journal of Heart and Lung Transplantation - August 31, 2022 Category: Transplant Surgery Authors: Sameer K Singh, Koji Takeda Tags: Editorial Source Type: research

Comparing Velocity and Mean Arterial Pressure to Assess Pulsatility in Patients with Continuous Flow Left Ventricular Assist Devices
An increasing number of end-stage heart failure patients are supported by continuous-flow Left Ventricular Assist Devices (cfLVADs). In these patients, accurate assessment of arterial pulsatility remains a challenge because of diminished pulse pressure. Limited pulsatility in modern cfLVADs itself can be associated with adverse events such as stroke. Our study investigates the value of simultaneous arterial pressure and arterial blood velocity assessment in cfLVAD patients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: S. Emmanuel, A. Adji, P. Jansz, C. Hayward Tags: (871) Source Type: research

Chronic Rejection and Atherosclerosis in Post-Transplant Cardiovascular Mortality: Two Sides of the Same Coin
Cardiovascular disease (CVD) as defined by the American Heart Association includes ischaemic heart disease, stroke, heart failure and thromboembolism [1]. Solid organ transplantation is associated with an increased risk of CVD morbidity and mortality [2], a relationship which was first observed in the context of kidney transplantation by Foley in 1998 [3]. This manifests clinically as an increased rate of major adverse cardiovascular events (MACE), defined as the composite of cardiac death, non-fatal myocardial infarction, non-fatal stroke, unstable angina and heart failure [4,5].
Source: Heart, Lung and Circulation - November 27, 2021 Category: Cardiology Authors: Afolarin A. Otunla, Kumaran Shanmugarajah, Maria Lucia Madariaga, Alun H. Davies, Joseph Shalhoub Tags: Editorial Source Type: research

Peripheral microvascular dysfunction is associated with plaque progression and adverse long ‐term outcomes in heart transplant patients
ConclusionsPeripheral endothelial dysfunction is associated with increased plaque progression and adverse long-term cardiovascular outcomes in transplant patients. PED assessment might be a useful clinical tool for risk stratification after heart transplantation.
Source: ESC Heart Failure - September 12, 2021 Category: Cardiology Authors: Ilke Ozcan, Takumi Toya, Michel T. Corban, Ali Ahmad, Lilach O. Lerman, Sudhir S. Kushwaha, Amir Lerman Tags: Original Research Article Source Type: research

Predicting the survivals and favorable neurologic outcomes after targeted temperature management by artificial neural networks
CONCLUSIONS: The ANN-based models achieved good performance to predict the survival and favorable neurologic outcomes after TTM. The models proposed have clinical value to assist in decision-making.PMID:34330620 | DOI:10.1016/j.jfma.2021.07.004
Source: J Formos Med Assoc - July 31, 2021 Category: General Medicine Authors: Wei-Ting Chiu Chen-Chih Chung Chien-Hua Huang Yu-San Chien Chih-Hsin Hsu Cheng-Hsueh Wu Chen-Hsu Wang Hung-Wen Chiu Lung Chan Source Type: research

Cerebral Vasoreactivity in HeartMate 3 Patients
While rates of stroke have declined with the HeartMate3 (HM3) continuous flow (CF) left ventricular assist device (LVAD), the impact of non-pulsatile flow and artificial pulse physiology on cerebrovascular function is not known. We hypothesized that improved hemodynamics and artificial pulse physiology of HM3 patients would augment cerebrovascular metabolic reactivity (CVR) compared with HeartMate II (HMII) CF-LVAD and heart failure (HF) patients.
Source: The Journal of Heart and Lung Transplantation - May 21, 2021 Category: Transplant Surgery Authors: Eric J. St öhr, Ruiping Ji, Koichi Akiyama, Giulio Mondellini, Lorenzo Braghieri, Alberto Pinsino, John R. Cockcroft, Melana Yuzefpolskaya, Amrin Amlani, Veli K. Topkara, Hiroo Takayama, Yoshifumi Naka, Nir Uriel, Koji Takeda, Paolo C. Colombo, Barry J. Tags: Original Research Article Source Type: research

Bridge from Central Extracorporeal Life Support to Durable LVAD in Acute Heart Failure Elevates a Risk of Stroke Long-Term
This study aimed to review outcomes of this bridge strategy from central ECLS to durable LVAD, as compared to those of primary LVAD implantation.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: K. Tonai, S. Fukushima, N. Tadokoro, N. Fukushima, T. Fujita Tags: (994) Source Type: research

Arterial Pulsatility in Patients with Continuous Flow Left Ventricular Assist Device Support: Comparing Velocity and Mean Arterial Pressure
An increasing number of end-stage heart failure patients are supported by continuous-flow Left Ventricular Assist Devices (cfLVADs) as a bridge to heart transplantation. Accurate assessment of arterial pulsatility remains a challenge because of diminished pulse pressure, which itself can be associated with adverse events such as gastrointestinal bleeding and stroke. Our study investigates the value of simultaneous arterial pressure and arterial blood velocity assessment in cfLVAD patients.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: S. Emmanuel, A. Adji, D. Robson, P. Jain, C. Hayward Tags: 1138 Source Type: research

079 Assessing Arterial Pulsatility in Patients With Continuous Flow Left Ventricular Assist Device Support
An increasing number of end-stage heart failure patients are supported by continuous-flow Left Ventricular Assist Devices (cfLVADs) as a bridge to heart transplantation. In these patients, accurate assessment of arterial pulsatility remains a challenge because of diminished pulse pressure, which itself can be associated with adverse events such as gastrointestinal bleeding and stroke. Our study investigates the value of simultaneous arterial pressure and arterial flow velocity assessment in cfLVAD patients.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: A. Adji, S. Emmanuel, P. Jain, C. Hayward Source Type: research

Cardiac Transplantation for Cancer Involving the Heart
Cardiac Cancer (CC) that arises from or involves the heart can present as heart failure, chest pain, stroke or another thromboembolic event. Although patients with CC have limited treatment options, in other organ cancers such as hepatocellular carcinoma, liver transplant improves 5-year overall survival in carefully selected patients1. For CC, however, the benefit of replacing the cancerous heart is uncertain because one-year survival is generally estimated around 50% after this rare operation.
Source: The Journal of Heart and Lung Transplantation - May 23, 2020 Category: Transplant Surgery Authors: Matthew Wingo, Andreas R. de Biasi, Yasuhiro Shudo, Vijaya Bharathi, Anthony Blackburn, Mario Gaudino, Leonard N. Girardi, Y. Joseph Woo Tags: Research Correspondence Source Type: research

Risk assessment in PAH using quantitative CMR tricuspid regurgitation: relation to heart catheterization
ConclusionsA clear trend towards worse outcome with larger TRV or TR% was shown; however, the number of events was insufficient for significant outcome differences. Prognostic value of quantitative TR should be investigated in a larger multicentre cohort. Effective RV ejection fraction may be considered an improved measure of RV function in PAH.
Source: ESC Heart Failure - May 5, 2020 Category: Cardiology Authors: Erik Hedstr öm, Anna Bredfelt, Göran Rådegran, Håkan Arheden, Ellen Ostenfeld Tags: Original Research Article Source Type: research