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Specialty: Hematology
Source: Journal of Thrombosis and Haemostasis

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Total 139 results found since Jan 2013.

Association of Stroke Risk Biomarkers with Stroke Symptoms: The Reasons for Geographic And Racial Differences in Stroke Cohort
ConclusionsStrong associations of stroke risk biomarkers with stroke symptoms in persons without a clinical history of cerebrovascular disease support a hypothesis that some of these stroke symptoms represent unrecognized cerebrovascular disease. Future work is needed to determine whether these biomarkers identify persons with stroke symptoms who have a particularly high stroke risk.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - November 3, 2016 Category: Hematology Authors: K. K. Landry, K. S. Alexander, N. A. Zakai, S. E. Judd, D. O. Kleindorfer, V. J. Howard, G. Howard, M. Cushman Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

ABO Blood Type and Stroke Risk: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study
ConclusionBlood type AB is associated with an increased risk of stroke that is not attenuated by conventional stroke risk factors and factor VIII levels were associated with 60% of the association. While blood type AB is rare in the U.S. population, it is a significant stroke risk factor and may play an important role in stroke risk in these individuals.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - January 21, 2014 Category: Hematology Authors: Neil A. Zakai, Suzanne E. Judd, Kristine Alexander, Leslie A. McClure, Brett M. Kissela, George Howard, Mary Cushman Tags: Original Article ‐ Vascular Biology Source Type: research

ABO blood type and stroke risk: the REasons for Geographic And Racial Differences in Stroke Study
ConclusionBlood type AB is associated with an increased risk of stroke that is not attenuated by conventional stroke risk factors, and factor VIII levels were associated with 60% of the association. While blood type AB is rare in the US population, it is a significant stroke risk factor and may play an important role in stroke risk in these individuals.
Source: Journal of Thrombosis and Haemostasis - April 11, 2014 Category: Hematology Authors: N. A. Zakai, S. E. Judd, K. Alexander, L. A. McClure, B. M. Kissela, G. Howard, M. Cushman Tags: Original Article Source Type: research

Procarboxypeptidase U (proCPU, TAFI, proCPB2) in cerebrospinal fluid during ischemic stroke is associated with stroke progression, outcome and blood ‐brain barrier dysfunction
ConclusionsProCPU is increased in CSF during hyperacute ischemic stroke and are associated with stroke progression and outcome after 3 months, most likely due to BBB dysfunction in the hyperacute phase of ischemic stroke.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - December 1, 2017 Category: Hematology Authors: Joachim C Mertens, Dorien Leenaerts, Raf Brouns, Sebastiaan Engelborghs, Margareta Ieven, Peter P De Deyn, Anne ‐Marie Lambeir, Dirk Hendriks Tags: Brief Report – Fibrinolysis Source Type: research

Comorbidity and the increased mortality after hospitalization for stroke: a population ‐based cohort study
ConclusionComorbidity, notably cancer and advanced renal or liver disease, increased one‐year mortality after stroke beyond the combined effects expected from either disease acting alone.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - November 1, 2017 Category: Hematology Authors: P. Corraini, S. K. Sz épligeti, Victor W. Henderson, Anne G. Ording, Erzsébet Horváth‐Puhó, Henrik T. Sørensen Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

Severe stroke: patient profile and predictors of favorable outcome
Conclusions:  Severe stroke presentation is predicted by multiple clinical, radiologic and metabolic variables, several of which are modifiable. Predictors in the 28% of patients with favorable outcome despite presenting with severe stroke include hypolipemic pretreatment, lower acute temperature, lower glucose levels at 24 h, and arterial recanalization.
Source: Journal of Thrombosis and Haemostasis - January 27, 2013 Category: Hematology Authors: O. BILL, P. ZUFFEREY, M. FAOUZI, P. MICHEL Tags: ORIGINAL ARTICLE Source Type: research

Filaggrin loss ‐of‐function mutations as risk factors for ischemic stroke in the general population
ConclusionIn this study of 97,174 individuals from the Danish general population, FLG loss‐of‐function mutations were associated with increased ischemic stroke risk; however, residual confounding is a possibility.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - December 31, 2016 Category: Hematology Authors: Anette Varbo, B ørge G. Nordestgaard, Marianne Benn Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

Retinal vein and artery occlusions:a risk factor for stroke in atrial fibrillation
ConclusionA history of retinal arterial or retinal venous occlusion is associated with an increased risk of stroke/TE/TIA in patients with atrial fibrillation. Thus, prior retinal vascular occlusion may be considered a previous thromboembolic event when evaluating stroke risk in patients with atrial fibrillation.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - May 11, 2013 Category: Hematology Authors: Christine Benn Christiansen, Gregory YH Lip, Morten Lamberts, Gunnar Gislason, Christian Torp‐Pedersen, Jonas Bjerring Olesen Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research

Neutrophil to Lymphocyte Ratio (NLR) and Risk of First Episode Stroke in Patients with Atrial Fibrillation: A Cohort Study
ConclusionsNLR is directly associated with the risk of stroke in patients with atrial fibrillation. Future studies are needed to replicate these findings.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - May 18, 2015 Category: Hematology Authors: Walid Saliba, Ofra Barnett‐Griness, Mazen Elias, Gad Rennert Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

Neutrophil to lymphocyte ratio and risk of a first episode of stroke in patients with atrial fibrillation: a cohort study
ConclusionsThe neutrophil to lymphocyte ratio is directly associated with the risk of stroke in patients with atrial fibrillation. Future studies are needed to replicate these findings.
Source: Journal of Thrombosis and Haemostasis - September 14, 2015 Category: Hematology Authors: W. Saliba, O. Barnett‐Griness, M. Elias, G. Rennert Tags: In Focus Source Type: research

The role of CHADS2 and CHA2DS2‐VASc scores in the prediction of stroke in individuals without atrial fibrillation: a population‐based study
ConclusionsCHADS2 and CHA2DS2‐VASc scores have a relatively high performance for stroke/TIA prediction in individuals without AF which is comparable to their performance in patients with AF.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - February 29, 2016 Category: Hematology Authors: Walid Saliba, Naomi Gronich, Ofra Barnett‐Griness, Gad Rennert Tags: Original Article Source Type: research

C ‐reactive protein gene polymorphism predicts the risk of thromboembolic stroke in patients with atrial fibrillation: a more than 10‐year prospective follow‐up study
ConclusionThe CRP triallelic polymorphism and the CRP level are associated with the risk of incident thromboembolic stroke in patients with AF.
Source: Journal of Thrombosis and Haemostasis - July 14, 2017 Category: Hematology Authors: S. ‐N. Chang, L.‐P. Lai, F.‐T. Chiang, J.‐L. Lin, J.‐J. Hwang, C.‐T. Tsai Tags: Original Article Source Type: research

proMetalloproteinase‐10 is associated with brain damage and clinical outcome in acute ischemic stroke
ConclusionsIncreased serum proMMP‐10 after acute ischemic stroke, associated with TNFα, is a new marker of brain damage and poor outcome.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 7, 2013 Category: Hematology Authors: José A. Rodríguez, Tomás Sobrino, Josune Orbe, Ana Purroy, Eduardo Martínez‐Vila, José Castillo, José A. Páramo Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

Retinal vein and artery occlusions: a risk factor for stroke in atrial fibrillation
ConclusionsA history of retinal arterial or retinal venous occlusion is associated with an increased risk of stroke/TE/TIA in patients with atrial fibrillation. Thus, prior retinal vascular occlusion may be considered as a previous thromboembolic event when evaluating stroke risk in patients with atrial fibrillation.
Source: Journal of Thrombosis and Haemostasis - August 14, 2013 Category: Hematology Authors: C. B. Christiansen, G. Y. H. Lip, M. Lamberts, G. Gislason, C. Torp‐Pedersen, J. B. Olesen Tags: Original Article Source Type: research

Lack of secondary microthrombosis after thrombin‐induced stroke in mice and non‐human primates
ConclusionsOur data demonstrates that secondary microthrombosis does not occur after thrombin‐induced stroke. In view of that, the pathophysiological roles of hematologic players promoting or protecting from secondary microthrombosis (such as Factor XII, von Willebrand Factor, T‐cells…) deserve to be reevaluated in non‐TMVO stroke models.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - December 16, 2013 Category: Hematology Authors: Maxime Gauberti, Sara Martinez Lizarrondo, Cyrille Orset, Denis Vivien Tags: Brief Report ‐ Vascular Biology Source Type: research